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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Review

Update on Asthma–COPD Overlap (ACO): A Narrative Review

Evgeni Mekov1 Department of Occupational Diseases, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria
,
Alexa Nuñez2 Pneumology Department, Hospital Universitari Vall d´Hebron, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, SpainORCID Iconhttps://orcid.org/0000-0003-4067-0466
ORCID Icon,
Don D Sin3 Centre for Heart Lung Innovation, St. Paul’s Hospital, Department of Medicine (Respiratory Division), University of British Columbia, Vancouver, BC, CanadaORCID Iconhttps://orcid.org/0000-0002-0756-6643
ORCID Icon,
Masakazu Ichinose4 Academic Center of Osaki Citizen Hospital, Miyagi, Japan
,
Chin Kook Rhee5 Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-4533-7937
ORCID Icon,
Diego Jose Maselli6 Division of Pulmonary Diseases & Critical Care, University of Texas Health, South Texas Veterans Health Care System, San Antonio, TX, USA
,
Andréanne Coté7 Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, QC, Canada
,
Charlotte Suppli Ulrik8 Department of Pulmonary Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark;9 Institute of Clinical Medicine, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0001-8689-3695
ORCID Icon,
François Maltais7 Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, QC, CanadaORCID Iconhttps://orcid.org/0000-0002-6809-4651
ORCID Icon,
Antonio Anzueto6 Division of Pulmonary Diseases & Critical Care, University of Texas Health, South Texas Veterans Health Care System, San Antonio, TX, USA
&
Marc Miravitlles2 Pneumology Department, Hospital Universitari Vall d´Hebron, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9850-9520
ORCID Icon show all
Pages 1783-1799 | Published online: 17 Jun 2021

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Norihiro Harada, Naoyuki Makita, Kenya Fukui, Kenichiro Nishida, Kaori Oneda & Naoki Tashiro. (2023) A Retrospective Claims Database Study to Clarify Disease Burden of Severe Asthma Patients with Type 2 High or Low Inflammation. Journal of Asthma and Allergy 16, pages 83-93.
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Shu Hashimoto, Yuri Yoshida, Naoyuki Makita, Ryoko Sorimachi, Satoko Sugaya, Yoshifumi Arita, Nobuya Hayashi, Naoki Tashiro & Masakazu Ichinose. (2023) Real-World Evidence on the Diagnostic and Clinical Characteristics of Asthma in Japanese Patients with COPD: The ACO Japan Cohort Study. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 37-46.
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Stephen A. Brunton & D. Kyle Hogarth. (2023) Overuse of long-acting β2-agonist/inhaled corticosteroids in patients with chronic obstructive pulmonary disease: time to rethink prescribing patterns. Postgraduate Medicine 0:0, pages 1-19.
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Edwina Veerasingam, Zhiwei Gao, Jeremy Beach & Ambikaipakan Senthilselvan. (2023) Sex-specific characteristics for the coexistence of asthma and COPD in the Canadian population: a cross-sectional analysis of CLSA data. Journal of Asthma 60:6, pages 1255-1267.
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Subash S Heraganahally, Timothy P Howarth, Angus Lloyd, Elisha White, Antony Veale & Helmi Ben Saad. (2022) The Prevalence of Bronchodilator Responsiveness “Asthma” Among Adult Indigenous Australians Referred for Lung Function Testing in the Top End Northern Territory of Australia. Journal of Asthma and Allergy 15, pages 1305-1319.
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Richard Kraemer, Fabian Gardin, Hans-Jürgen Smith, Florent Baty, Jürg Barandun, Andreas Piecyk, Stefan Minder, Jörg Salomon, Martin Frey, Martin H Brutsche & Heinrich Matthys. (2022) Functional Predictors Discriminating Asthma–COPD Overlap (ACO) from Chronic Obstructive Pulmonary Disease (COPD). International Journal of Chronic Obstructive Pulmonary Disease 17, pages 2723-2743.
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William D. Sanders. (2023) Asthma Chronic Obstructive Pulmonary Disease Overlap. Physician Assistant Clinics 8:4, pages 739-747.
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Neil C. Thomson. (2022) The Role of Smoking in Asthma and Chronic Obstructive Pulmonary Disease Overlap. Immunology and Allergy Clinics of North America 42:3, pages 615-630.
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Franziska C. Trudzinski, Rudolf A. Jörres, Peter Alter, Julia Walter, Henrik Watz, Andrea Koch, Matthias John, Marek Lommatzsch, Claus F. Vogelmeier, Hans-Ulrich Kauczor, Tobias Welte, Jürgen Behr, Amanda Tufman, Robert Bals, Felix J. F. Herth, Kathrin Kahnert, Stefan Andreas, Robert Bals, Jürgen Behr, Kathrin Kahnert, Burkhard Bewig, Roland Buhl, Ralf Ewert, Beate Stubbe, Joachim H. Ficker, Manfred Gogol, Christian Grohé, Rainer Hauck, Matthias Held, Berthold Jany, Markus Henke, Felix Herth, Gerd Höffken, Hugo A. Katus, Anne-Marie Kirsten, Henrik Watz, Rembert Koczulla, Klaus Kenn, Juliane Kronsbein, Cornelia Kropf-Sanchen, Christoph Lange, Peter Zabel, Michael Pfeifer, Winfried J. Randerath, Werner Seeger, Michael Studnicka, Christian Taube, Helmut Teschler, Hartmut Timmermann, J. Christian Virchow, Claus Vogelmeier, Ulrich Wagner, Tobias Welte & Hubert Wirtz. (2022) Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET. Scientific Reports 12:1.
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Evangelia Fouka, Andriana I. Papaioannou, Georgios Hillas & Paschalis Steiropoulos. (2022) Asthma-COPD Overlap Syndrome: Recent Insights and Unanswered Questions. Journal of Personalized Medicine 12:5, pages 708.
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Jinlv Qin, Guizuo Wang & Dong Han. (2022) Benefits of LAMA in patients with asthma-COPD overlap: A systematic review and meta-analysis. Clinical Immunology 237, pages 108986.
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Cheng-Sen Cai & Jun Wang. (2022) Factors Influencing the Stability of Blood Eosinophils Counts in Chronic Obstructive Pulmonary Disease Patients. Canadian Respiratory Journal 2022, pages 1-6.
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Clarus Leung & Don D. Sin. (2022) Asthma-COPD Overlap. Chest 161:2, pages 330-344.
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Sukanya Tongdee, Bundit Sawunyavisuth, Wattana Sukeepaisarnjaroen, Sittichai Khamsai & Kittisak Sawanyawisuth. (2021) Clinical factors predictive of appropriate treatment in COPD: a community hospital setting. Drug Target Insights 15, pages 21-25.
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