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Review

Current research for a vaccine against Lassa hemorrhagic fever virus

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Pages 2519-2527 | Published online: 14 Aug 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Yu Bai, Qian Wang, Mingchen Liu, Lianlian Bian, Jianyang Liu, Fan Gao, Qunying Mao, Zhongfang Wang, Xing Wu, Miao Xu & Zhenglun Liang. (2022) The next major emergent infectious disease: reflections on vaccine emergency development strategies. Expert Review of Vaccines 21:4, pages 471-481.
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Anahita Fathi, Christine Dahlke & Marylyn M. Addo. (2019) Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens. Human Vaccines & Immunotherapeutics 15:10, pages 2269-2285.
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Jingjing Jiang, Preeti Banglore, Kathleen A. Cashman, Connie S. Schmaljohn, Katherine Schultheis, Holly Pugh, Jacklyn Nguyen, Laurent M. Humeau, Kate E. Broderick & Stephanie J. Ramos. (2019) Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques. Human Vaccines & Immunotherapeutics 15:9, pages 2066-2074.
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Articles from other publishers (42)

Abayomi Ayotunde Ayoade, Oluwaseyi Aliu & Oyedepo Taiye. (2024) The effect of treatment compliance on the dynamics and control of Lassa fever: an insight from mathematical modeling. SeMA Journal.
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Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C. Boyington, Tatsiana Bylund, Sam Charaf, Steven J. Chen, Haijuan Du, Amy R. Henry, Tracy Liu, Edward K. Sarfo, Chaim A. Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C. Douek, John R. Mascola, David D. Ho, Mitchell Ho & Peter D. Kwong. (2024) Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature Communications 15:1.
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Giorgia Sulis, Alexandra Peebles & Nicole E. Basta. (2023) Lassa fever vaccine candidates: A scoping review of vaccine clinical trials. Tropical Medicine & International Health 28:6, pages 420-431.
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Vladimir A. Markin. (2023) Immunogenesis in Lassa fever and prospects for vaccine development. Journal of microbiology, epidemiology and immunobiology 100:2, pages 228-239.
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Takeshi Saito, Rachel A. Reyna, Satoshi Taniguchi, Kirsten Littlefield, Slobodan Paessler & Junki Maruyama. (2023) Vaccine Candidates against Arenavirus Infections. Vaccines 11:3, pages 635.
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Jérémie Prévost, Bryce M. Warner & David Safronetz. (2023) Multitasking to prevent viral haemorrhagic fevers. Nature Microbiology 8:1, pages 8-9.
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Igor José dos Santos Nascimento, Leandro Rocha Silva & Edeildo Ferreira da Silva-Júnior. 2023. Viral Infections and Antiviral Therapies. Viral Infections and Antiviral Therapies 169 209 .
Claudia Ferreira, Marie-Françoise J. Doursout & Joselito S. BalingitClaudia Ferreira, Marie-Françoise J. Doursout & Joselito S. Balingit. 2023. 2000 Years of Pandemics. 2000 Years of Pandemics 295 324 .
Adejoke Adijat Joseph, Olumuyiwa John Fasipe, Oluyemi Adesoji Joseph & Olalekan Aliu Olatunji. (2022) Contemporary and emerging pharmacotherapeutic agents for the treatment of Lassa viral haemorrhagic fever disease. Journal of Antimicrobial Chemotherapy 77:6, pages 1525-1531.
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Joana C. Antunes, Inês P. Moreira, Fernanda Gomes, Fernando Cunha, Mariana Henriques & Raúl Fangueiro. (2022) Recent Trends in Protective Textiles against Biological Threats: A Focus on Biological Warfare Agents. Polymers 14:8, pages 1599.
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Albert To, Chih-Yun Lai, Teri Ann S. Wong, Madhuri Namekar, Michael M. Lieberman & Axel T. Lehrer. (2022) Adjuvants Differentially Modulate the Immunogenicity of Lassa Virus Glycoprotein Subunits in Mice. Frontiers in Tropical Diseases 3.
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Lilia I. Melnik. 2023. Lassa Fever: Epidemiology, Immunology, Diagnostics, and Therapeutics. Lassa Fever: Epidemiology, Immunology, Diagnostics, and Therapeutics 111 145 .
Pushpendra Kumar, Vedat Suat Erturk, Abdullahi Yusuf & Tukur Abdulkadir Sulaiman. (2021) Lassa hemorrhagic fever model using new generalized Caputo-type fractional derivative operator. International Journal of Modeling, Simulation, and Scientific Computing 12:06, pages 2150055.
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Xueqin Zhu, Yang Liu, Jiao Guo, Junyuan Cao, Zonglin Wang, Gengfu Xiao & Wei Wang. (2021) Effects of N-Linked Glycan on Lassa Virus Envelope Glycoprotein Cleavage, Infectivity, and Immune Response. Virologica Sinica 36:4, pages 774-783.
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Frederick Hansen, Michael A. Jarvis, Heinz Feldmann & Kyle Rosenke. (2021) Lassa Virus Treatment Options. Microorganisms 9:4, pages 772.
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Meirong Wang, Ruihua Li, Yaohui Li, Changming Yu, Xiangyang Chi, Shipo Wu, Shulin Liu, Junjie Xu & Wei Chen. (2021) Construction and Immunological Evaluation of an Adenoviral Vector-Based Vaccine Candidate for Lassa Fever. Viruses 13:3, pages 484.
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Bryce M. Warner. (2021) Pathogen Dose in Animal Models of Hemorrhagic Fever Virus Infections and the Potential Impact on Studies of the Immune Response. Pathogens 10:3, pages 275.
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E. I. Kazachinskaya, V. S. Aripov, A. V. Zaikovskaya & A. M. Shestopalov. (2021) Lassa virus: characterization of infectious agent, biological models for pathogenesis studies and variants of vaccine. Medical Immunology (Russia) 23:1, pages 35-48.
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O C Collins & J E Okeke. (2021) Analysis and control measures for Lassa fever model under socio-economic conditions. Journal of Physics: Conference Series 1734:1, pages 012049.
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Akinyemi Ademola Omoniyi, Samuel Sunday Adebisi, Sunday Abraham Musa, James Oliver Nzalak, Barnabas Danborno, Zainab Mahmood Bauchi, Iswat Taiwo Badmus, Oluwasegun Davis Olatomide, Olalekan Jerry Oladimeji & Jens Randel Nyengaard. (2021) Designing a multi-epitope vaccine against the Lassa virus through reverse vaccinology, subtractive proteomics, and immunoinformatics approaches. Informatics in Medicine Unlocked 25, pages 100683.
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Susanne Modrow, Uwe Truyen & Hermann SchätzlSusanne Modrow, Uwe Truyen & Hermann Schätzl. 2021. Molekulare Virologie. Molekulare Virologie 403 474 .
Kolawole Salami, Nathalie Imbault, Aljoscha Erlebach, Johanna Urban, Mike Zoglowek & Nadia G. Tornieporth. (2020) A systematic scorecard-based approach to site assessment in preparation for Lassa fever vaccine clinical trials in affected countries. Pilot and Feasibility Studies 6:1.
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Ifeanyi Sunday Onah & Obiora Cornelius Collins. (2020) Dynamical System Analysis of a Lassa Fever Model with Varying Socioeconomic Classes. Journal of Applied Mathematics 2020, pages 1-12.
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Megan L. Heinrich, Matthew L. Boisen, Diana K. S. Nelson, Duane J. Bush, Robert W. Cross, Anatoliy P. Koval, Andrew R. Hoffmann, Brandon J. Beddingfield, Kathryn M. Hastie, Megan M. Rowland, Irina Aimukanova, Sophia Koval, Raju Lathigra, Viktoriya Borisevich, Mambu Momoh, John Demby Sandi, Augustine Goba, lkponmwosa Odia, Francis Baimba, John O. Aiyepada, Benevolence Ebo, Philomena Eromon, Chinedu Ugwu, Onikepe Folarin, Testimony Olumade, MacDonald N. Onyechi, Johnson Etafo, Rashidat Adeyemi, Elijah E. Ella, Maryam Aminu, Simji S. Gomerep, Matthew Afam Eke, Olusola Ogunsanya, George O. Akpede, Danny O. Asogun, Sylvanus A. Okogbenin, Peter O. Okokhere, Johan Holst, Jeffrey G. Shaffer, John S. Schieffelin, Thomas W. Geisbert, Erica Ollmann Saphire, Christian T. Happi, Donald S. Grant, Robert F. Garry & Luis M. Branco. (2020) Antibodies from Sierra Leonean and Nigerian Lassa fever survivors cross-react with recombinant proteins representing Lassa viruses of divergent lineages. Scientific Reports 10:1.
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Peter D. Kwong, Brandon J. DeKosky & Jeffrey B. Ulmer. (2020) Antibody-guided structure-based vaccines. Seminars in Immunology 50, pages 101428.
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Ifeanyi Sunday Onah, Obiora Cornelius Collins, Praise-God Uchechukwu Madueme & Godwin Christopher Ezike Mbah. (2020) Dynamical System Analysis and Optimal Control Measures of Lassa Fever Disease Model. International Journal of Mathematics and Mathematical Sciences 2020, pages 1-18.
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Francis Ifedayo Ibukun. (2020) Inter-Lineage Variation of Lassa Virus Glycoprotein Epitopes: A Challenge to Lassa Virus Vaccine Development. Viruses 12:4, pages 386.
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Danny A. Asogun, Stephan Günther, George O. Akpede, Chikwe Ihekweazu & Alimuddin Zumla. (2019) Lassa Fever. Infectious Disease Clinics of North America 33:4, pages 933-951.
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Jyothi Purushotham, Teresa Lambe & Sarah C. Gilbert. (2019) Vaccine platforms for the prevention of Lassa fever. Immunology Letters 215, pages 1-11.
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Manish Goyal, Haci Mehmet Baskonus & Amit Prakash. (2019) An efficient technique for a time fractional model of lassa hemorrhagic fever spreading in pregnant women. The European Physical Journal Plus 134:10.
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Junki Maruyama, Elizabeth J. Mateer, John T. Manning, Rachel Sattler, Alexey V. Seregin, Natalya Bukreyeva, Frank R. Jones, Joseph P. Balint, Elizabeth S. Gabitzsch, Cheng Huang & Slobodan Paessler. (2019) Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs. Vaccine 37:45, pages 6824-6831.
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Markus H Kainulainen, Jessica R Spengler, Stephen R Welch, JoAnn D Coleman-McCray, Jessica R Harmon, Florine E M Scholte, Cynthia S Goldsmith, Stuart T Nichol, César G Albariño & Christina F Spiropoulou. (2019) Protection From Lethal Lassa Disease Can Be Achieved Both Before and After Virus Exposure by Administration of Single-Cycle Replicating Lassa Virus Replicon Particles. The Journal of Infectious Diseases 220:8, pages 1281-1289.
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Giada Mattiuzzo, Emma M. Bentley & Mark Page. (2019) The Role of Reference Materials in the Research and Development of Diagnostic Tools and Treatments for Haemorrhagic Fever Viruses. Viruses 11:9, pages 781.
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Derek R. Stein, Patrycja Sroga, Bryce M. Warner, Yvon Deschambault, Guillaume Poliquin & David Safronetz. (2019) Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines. Emerging Infectious Diseases 25:8, pages 1563-1566.
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Lauren E Garnett & James E Strong. (2019) Lassa fever: With 50 years of study, hundreds of thousands of patients and an extremely high disease burden, what have we learned?. Current Opinion in Virology 37, pages 123-131.
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Kolawole Salami, Dimitrios Gouglas, Connie Schmaljohn, Melanie Saville & Nadia Tornieporth. (2019) A review of Lassa fever vaccine candidates. Current Opinion in Virology 37, pages 105-111.
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Brett Beitzel, Christine E Hulseberg & Gustavo Palacios. (2019) Reverse genetics systems as tools to overcome the genetic diversity of Lassa virus. Current Opinion in Virology 37, pages 91-96.
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Xiaoyu Zhang, Feihu Yan, Ke Tang, Qing Chen, Jiamei Guo, Wenjun Zhu, Shihua He, Logan Banadyga, Xiangguo Qiu & Ying Guo. (2019) Identification of a clinical compound losmapimod that blocks Lassa virus entry. Antiviral Research 167, pages 68-77.
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C. E. Hulseberg, L. Fénéant, K. M. Szymańska-de Wijs, N. P. Kessler, E. A. Nelson, C. J. Shoemaker, C. S. Schmaljohn, S. J. Polyak & J. M. White. (2019) Arbidol and Other Low-Molecular-Weight Drugs That Inhibit Lassa and Ebola Viruses. Journal of Virology 93:8.
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Derek R. Stein, Bryce M. Warner, Geoff Soule, Kevin Tierney, Kathy L. Frost, Stephanie Booth & David Safronetz. (2019) A recombinant vesicular stomatitis-based Lassa fever vaccine elicits rapid and long-term protection from lethal Lassa virus infection in guinea pigs. npj Vaccines 4:1.
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Laura T Mazzola & Cassandra Kelly-Cirino. (2019) Diagnostics for Lassa fever virus: a genetically diverse pathogen found in low-resource settings. BMJ Global Health 4:Suppl 2, pages e001116.
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Federico Perdomo-Celis, Maria S. Salvato, Sandra Medina-Moreno & Juan C. Zapata. (2019) T-Cell Response to Viral Hemorrhagic Fevers. Vaccines 7:1, pages 11.
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