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Original Research

The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

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Pages 57-65 | Published online: 28 Dec 2017

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Kai Wang, Qing Gao, Tingting Zhang, Jinqiu Rao, Liqin Ding & Feng Qiu. (2020) Inhibition of CYP2C9 by natural products: insight into the potential risk of herb-drug interactions. Drug Metabolism Reviews 52:2, pages 235-257.
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Articles from other publishers (16)

Xiaoyin Zhang, Zhanbo Xiong, Yue He, Nan Zheng, Shengguo Zhao & Jiaqi Wang. (2024) Epiberberine: a potential rumen microbial urease inhibitor to reduce ammonia release screened by targeting UreG. Applied Microbiology and Biotechnology 108:1.
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Ze-Dong Xiang, Hui-Da Guan, Xiang Zhao, Qi Xie, Fu-Jie Cai, Zhe-Jun Xie, Rui Dang, Man-Lin Li & Chang-Hong Wang. (2024) Protoberberine alkaloids: A review of the gastroprotective effects, pharmacokinetics, and toxicity. Phytomedicine 126, pages 155444.
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Dar Junaid Bashir, Saliha Manzoor, Mobin Ahsan Siddiqui, Masarat Bashir, Nidhi, Shweta Rastogi, Indu Arora & Mohammed Samim. (2024) Nanosized epiberberine-loaded chitosan-collagen nanocomposites: synthesis and evaluation of their cognitive and AChE inhibition enhancing potential in a scopolamine-induced amnesia rat model. New Journal of Chemistry 48:7, pages 3166-3180.
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Li-ming Zhou, Jin-hua Fan, Min-min Xu, Meng-yuan Xiong, Qiao-jiao Wang, Xue Chai, Xiao-duo Li, Xue-gang Li & Xiao-li Ye. (2023) Epiberberine regulates lipid synthesis through SHP (NR0B2) to improve non-alcoholic steatohepatitis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869:4, pages 166639.
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Yaping Xiao, Jianling Deng, Chunming Li, Xiaobao Gong, Zhenwei Gui, Jieyao Huang, Yaru Zhang, Yan Liu, Xiaoli Ye & Xuegang Li. (2021) Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway. Phytomedicine 83, pages 153488.
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Dong-Jun Fu, Jun Li & Bin Yu. (2021) Annual review of LSD1/KDM1A inhibitors in 2020. European Journal of Medicinal Chemistry 214, pages 113254.
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Linqiu Liu, Junjun Li & Yang He. (2020) Multifunctional epiberberine mediates multi-therapeutic effects. Fitoterapia 147, pages 104771.
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Wei Zhou, Ziyi Chen, Yonghua Wang, Xiumin Li, Aiping Lu, Xizhuo Sun & Zhigang Liu. (2019) Systems Pharmacology-Based Method to Assess the Mechanism of Action of Weight-Loss Herbal Intervention Therapy for Obesity. Frontiers in Pharmacology 10.
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