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Drug Design, Development and Therapy Volume 13, 2019 - Issue
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Original Research

Emodin enhances antitumor effect of paclitaxel on human non-small-cell lung cancer cells in vitro and in vivo

Shuifang Chen1 Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang310003, People’s Republic of ChinaCorrespondence[email protected]
,
Zeying Zhang1 Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang310003, People’s Republic of China
&
Jianli Zhang1 Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang310003, People’s Republic of China
Pages 1145-1153 | Published online: 10 Apr 2019

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Luo Jiang & Rui Hou. (2020) Tetrandrine Reverses Paclitaxel Resistance in Human Ovarian Cancer via Inducing Apoptosis, Cell Cycle Arrest Through β-Catenin Pathway. OncoTargets and Therapy 13, pages 3631-3639.
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Rui Wang, Zhilin Luo, Hong Zhang & Tianhu Wang. (2019) Tanshinone IIA Reverses Gefitinib-Resistance In Human Non-Small-Cell Lung Cancer Via Regulation Of VEGFR/Akt Pathway. OncoTargets and Therapy 12, pages 9355-9365.
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Ye-Ru Tan & Yu Lu. (2022) Molecular mechanism of Rhubarb in the treatment of non-small cell lung cancer based on network pharmacology and molecular docking technology. Molecular Diversity.
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Wojciech Trybus, Ewa Trybus & Teodora Król. (2022) Emodin Sensitizes Cervical Cancer Cells to Vinblastine by Inducing Apoptosis and Mitotic Death. International Journal of Molecular Sciences 23:15, pages 8510.
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Yiqun Li, Kaiming Li, Yan Zhao, Yong Li, Dengke Li, Liangliang Shen, Qing Wang, Hsin-Sheng Yang & Zhenxiao Sun. (2022) Emodin-8-O-β-D-glucopyranoside, a natural hydroxyanthraquinone glycoside from plant, suppresses cancer cell proliferation via p21-CDKs-Rb axis. Toxicology and Applied Pharmacology 438, pages 115909.
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Yaming Ding, Zhang Zhen, Muhammad Azhar Nisar, Farman Ali, Riaz Ud Din, Muhammad Khan, Tafail Akbar Mughal, Gulzar Alam, Linlin Liu & Muhammad Zubair Saleem. (2022) Sesquiterpene Lactones Attenuate Paclitaxel Resistance Via Inhibiting MALAT1/STAT3/ FUT4 Axis and P-Glycoprotein Transporters in Lung Cancer Cells. Frontiers in Pharmacology 13.
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Qi Zheng, Shuo Li, Xiaojiaoyang Li & Runping Liu. (2021) Advances in the study of emodin: an update on pharmacological properties and mechanistic basis. Chinese Medicine 16:1.
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Guoqing Gu, Chenxi Hu, Kaiyuan Hui, Ting Chen, Huiqin Zhang & Xiaodong Jiang. (2021) NEAT 1 knockdown enhances the sensitivity of human non-small-cell lung cancer cells to anlotinib. Aging 13:10, pages 13941-13953.
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Ho-Sung Lee, In-Hee Lee, Kyungrae Kang, Sang-In Park, Tae-Wook Kwon & Dae-Yeon Lee. (2021) Uncovering the Anti-Lung-Cancer Mechanisms of the Herbal Drug FDY2004 by Network Pharmacology. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-15.
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Xinru Pang, Linlin Shao, Xiaojuan Nie, Haiyue Yan, Chao Li, Abrey J. Yeo, Martin F. Lavin, Qing Xia, Hua Shao, Gongchang Yu, Qiang Jia & Cheng Peng. (2021) Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition. International Immunopharmacology 91, pages 107277.
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Qiong Wu, Bo Zhao, Guangchao Sui & Jinming Shi. (2021) Phytochemicals Block Glucose Utilization and Lipid Synthesis to Counteract Metabolic Reprogramming in Cancer Cells. Applied Sciences 11:3, pages 1259.
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Shuai Peng, Jincheng Wang, Chang Lu, Zelin Xu, Jing-Jing Chai, Qing Ke & Xin-Zhou Deng. (2021) Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation. Oncology Letters 21:3.
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Yuying Li, Fang Guo, Tinggui Chen, Liwei Zhang, Zhuanhua Wang, Qiang Su & Liheng Feng. (2020) Design, Synthesis, Molecular Docking, and Biological Evaluation of New Emodin Anthraquinone Derivatives as Potential Antitumor Substances. Chemistry & Biodiversity 17:9.
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Hua-Zhong Ying, Chen-Huan Yu, Hao-Kun Chen, Huan-Huan Zhang, Jie Fang, Fang Wu & Wen-Ying Yu. (2020) Quinonoids: Therapeutic Potential for Lung Cancer Treatment. BioMed Research International 2020, pages 1-13.
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