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Drug Design, Development and Therapy Volume 14, 2020 - Issue
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Original Research

Chrysophanol Inhibits the Progression of Diabetic Nephropathy via Inactivation of TGF-β Pathway

Chuan Guo1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, People’s Republic of China;2 Department of Nephropathy, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, People’s Republic of China
,
Yarong Wang1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, People’s Republic of China
,
Yuanlin Piao1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, People’s Republic of China
,
Xiangrong Rao2 Department of Nephropathy, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, People’s Republic of China
&
Dehai Yin1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, People’s Republic of ChinaCorrespondence[email protected]
Pages 4951-4962 | Published online: 16 Nov 2020

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Hou-Hsun Liao, Hsiao-Tien Chen, Hanoch Livneh, Hua-Lung Huang, Ning-Sheng Lai, Ming-Chi Lu, Chia-Chou Yeh & Tzung-Yi Tsai. (2023) Integration of Chinese Herbal Medicine into Routine Care Was Related to Lower Risk of Chronic Kidney Disease in Patients with Rheumatoid Arthritis: A Population-Based Nested Case–Control Study in Taiwan. Journal of Multidisciplinary Healthcare 16, pages 1191-1201.
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Articles from other publishers (11)

Jinghua Sun, Juanjuan Han, Jie Dong, Xiaoyan Zhai & Ruiping Zhang. (2024) A kidney-targeted chitosan-melanin nanoplatform for alleviating diabetic nephropathy through modulation of blood glucose and oxidative stress. International Journal of Biological Macromolecules 264, pages 130663.
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Jiaxiang Pan, Yue Li, Xize Wu, Xue Pan, Chuang Liu, Haoyang Zhang, Linlin Wang, Xin Jiang, Jiaran Wang, Ningzi Zang, Lijian Pang & Xiaodong Lv. (2024) The mechanism of Shenlong Jianji treatment of idiopathic pulmonary fibrosis inhibits fibroblast-to-myofibroblast transformation via the TGF-β1/smads signaling pathway. Journal of Ethnopharmacology 322, pages 117507.
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Na Guo, Linlin Yang, Xiaozheng Wan, Dongze Qiu, Wenwen Sun & Huijuan Ma. (2023) Relationship between elevated circulating thrombospondin‐1 levels and vascular complications in diabetes mellitus. Journal of Diabetes Investigation 15:2, pages 197-207.
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Kavishankar Gawli & Kavya Sritha Bojja. (2024) Molecules and targets of antidiabetic interest. Phytomedicine Plus 4:1, pages 100506.
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XiaoQi Xuan, Xiao Pu, Yue Yang, JinLong Yang, YongLe Li, Hang Wu & JianGuo Xu. (2024) Plasma MCP-1 and TGF-β1 Levels are Associated with Kidney Injury in Children with Congenital Anomalies of the Kidney and Urinary Tract. Applied Biochemistry and Biotechnology.
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Fang Zhang, Rui Wu, Yanfang Liu, Shu Dai, Xinyan Xue, Yunxia Li & Xiaohong Gong. (2023) Nephroprotective and nephrotoxic effects of Rhubarb and their molecular mechanisms. Biomedicine & Pharmacotherapy 160, pages 114297.
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Elok Rifqi Firdiana, Elga Renjana, Melisnawati H. Angio & Linda Wige Ningrum. Analysis of anti-diabetic property of Aloe vera (L.) Burm.f. by in silico molecular docking. Analysis of anti-diabetic property of Aloe vera (L.) Burm.f. by in silico molecular docking.
Yangyang Wang, Fangwei Yu, Ao Li, Zijia He, Caiyan Qu, Caiying He, Xiao Ma & Huakui Zhan. (2022) The progress and prospect of natural components in rhubarb (Rheum ribes L.) in the treatment of renal fibrosis. Frontiers in Pharmacology 13.
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Liang-Pu Luo, Ping Suo, Li-Li Ren, Hong-Jiao Liu, Yamei Zhang & Ying-Yong Zhao. (2021) Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling Pathways. Frontiers in Pharmacology 12.
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Yanan Yang & Chongming Wu. (2021) Traditional Chinese Medicine in Ameliorating Diabetic Kidney Disease Via Modulating Gut Microbiota. Integrative Medicine in Nephrology and Andrology 8:1, pages 8.
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Siqing Ma, Heng Xu, Weihua Huang, Yongchao Gao, Honghao Zhou, Xiong Li & Wei Zhang. (2021) Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation. Frontiers in Physiology 12.
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