https://orcid.org/0000-0002-0349-7193
Citations (32)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
John N. Philoppes, Mohamed A. Abdelgawad, Mohammed A. S. Abourehab, Mohamed Sebak, Mostafa A. Darwish & Phoebe F. Lamie. (2023) Novel N-methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardio vascular risks. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 246-266.
Read now
Read now
Emad H. M. Hassanein, Fares E. M. Ali, Zuhair M. Mohammedsaleh, Ahmed M. Atwa & Mohamed Elfiky. (2023) The involvement of Nrf2/HO-1/cytoglobin and Ang-II/NF-κB signals in the cardioprotective mechanism of lansoprazole against cisplatin-induced heart injury. Toxicology Mechanisms and Methods 33:4, pages 316-326.
Read now
Read now
Articles from other publishers (30)
Huilin Liao, Yueqing Wang, Lili Zou, Yanmei Fan, Xinyue Wang, Xiancong Tu, Qiaobai Zhu, Jun Wang, Xiaowen Liu & Chuanjiang Dong. (2024) Relationship of mTORC1 and ferroptosis in tumors. Discover Oncology 15:1.
Crossref
Crossref
Ehab A. M. El-Shoura, Emad H. M. Hassanein, Hesham H. Taha, Abdel-Gawad S. Shalkami, Mohamed Mahmoud Hussein Hassanein, Fares E. M. Ali & Adel G. Bakr. (2024) Edaravone and obeticholic acid protect against cisplatin-induced heart toxicity by suppressing oxidative stress and inflammation and modulating Nrf2, TLR4/p38MAPK, and JAK1/STAT3/NF-κB signals. Naunyn-Schmiedeberg's Archives of Pharmacology.
Crossref
Crossref
D.H. Adeyemi, M.A. Hamed, D.T. Oluwole, A.I. Omole & R.E. Akhigbe. (2024) Acetate attenuates cyclophosphamide-induced cardiac injury via inhibition of NF-kB signaling and suppression of caspase 3-dependent apoptosis in Wistar rats. Biomedicine & Pharmacotherapy 170, pages 116019.
Crossref
Crossref
Al Shaima G. Abd El Salam, Mahmoud M. Samaha & Nesma A. Abd Elrazik. (2023) Cytoprotective effects of cinnamaldehyde and adipoRon against cyclophosphamide‐induced cardio-renal toxicity in rats: Insights into oxidative stress, inflammation, and apoptosis. International Immunopharmacology 124, pages 111044.
Crossref
Crossref
Fares E.M. Ali, Emad H.M. Hassanein, Ali H. El-Bahrawy, Mohamed S. Hemeda & Ahmed M. Atwa. (2023) Neuroprotective effect of lansoprazole against cisplatin-induced brain toxicity: Role of Nrf2/ARE and Akt/P53 signaling pathways. Journal of Chemical Neuroanatomy 132, pages 102299.
Crossref
Crossref
Emad H. M. Hassanein, Esam O. Kamel, Wail M. Gad-Elrab, Mohammed A. Ahmed, Zuhair M. Mohammedsaleh & Fares E. M. Ali. (2023) Lansoprazole attenuates cyclophosphamide-induced cardiopulmonary injury by modulating redox-sensitive pathways and inflammation. Molecular and Cellular Biochemistry 478:10, pages 2319-2335.
Crossref
Crossref
Ali Kardooni, Aida Bahrampour, Somaye Golmohammadi, Arsalan Jalili & Mohammad Mobin Alishahi. (2023) The Role of Epithelial Mesenchymal Transition (EMT) in Pathogenesis of Cardiotoxicity: Diagnostic & Prognostic Approach. Molecular Biotechnology 65:9, pages 1403-1413.
Crossref
Crossref
Emad H. M. Hassanein, Mostafa S. Abd El‐Maksoud, Islam M. Ibrahim, Esraa K. Abd‐alhameed, Hanan S. Althagafy, Nesma M. Mohamed & Samir A. Ross. (2023) The molecular mechanisms underlying anti‐inflammatory effects of galangin in different diseases. Phytotherapy Research 37:7, pages 3161-3181.
Crossref
Crossref
Nilanjan Ghosh, Leena Chacko, Hiranmoy Bhattacharya, Jayalakshmi Vallamkondu, Sagnik Nag, Abhijit Dey, Tanushree Karmakar, P. Hemachandra Reddy, Ramesh Kandimalla & Saikat Dewanjee. (2023) Exploring the Complex Relationship between Diabetes and Cardiovascular Complications: Understanding Diabetic Cardiomyopathy and Promising Therapies. Biomedicines 11:4, pages 1126.
Crossref
Crossref
Emad H.M. Hassanein, Wafaa R. Mohamed, Rasha M. Hussein & El-Shaimaa A. Arafa. (2023) Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling. International Immunopharmacology 117, pages 109969.
Crossref
Crossref
Emad H. M. Hassanein, Ahmed M. Sayed, Omnia A. M. Abd El-Ghafar, Zainab M. M. Omar, Eman K. Rashwan, Zuhair M. Mohammedsaleh, So Young Kyung, Jae Hyeon Park, Hyung Sik Kim & Fares E. M. Ali. (2023) Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways. Archives of Pharmacal Research 46:4, pages 339-359.
Crossref
Crossref
Fares E. M. Ali, Emad H. M. Hassanein, Omnia A. M. Abd El‐Ghafar, Eman K. Rashwan, Fayez M. Saleh & Ahmed M. Atwa. (2023) Exploring the cardioprotective effects of canagliflozin against cisplatin‐induced cardiotoxicity: Role of iNOS/NF‐κB, Nrf2, and Bax/cytochrome C/Bcl‐2 signals. Journal of Biochemical and Molecular Toxicology 37:4.
Crossref
Crossref
Reem S. Alruhaimi. (2023) Betulinic acid protects against cardiotoxicity of the organophosphorus pesticide chlorpyrifos by suppressing oxidative stress, inflammation, and apoptosis in rats. Environmental Science and Pollution Research 30:17, pages 51180-51190.
Crossref
Crossref
Nahed A. Mahmoud, Emad H.M. Hassanein, Etify A. Bakhite, Eman S. Shaltout & Ahmed M. Sayed. (2023) Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation. Life Sciences 314, pages 121313.
Crossref
Crossref
Wenjing Luo, Huiming Xu, Li Xu, Wei Jiang, Chen Chen, Yanyu Chang, Chunxin Liu, Zhenming Tian, Xiusheng Qiu, Chichu Xie, Xuejia Li, Haijia Chen, Shuiqing Lai, Longjun Wu, Yaxiong Cui, Changyong Tang & Wei Qiu. (2022)
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through
mTORC1
signaling activation
. Glia 71:2, pages 284-304.
Crossref
Crossref
Zehua Liang, Yuquan He & Xin Hu. (2022) Cardio-Oncology: Mechanisms, Drug Combinations, and Reverse Cardio-Oncology. International Journal of Molecular Sciences 23:18, pages 10617.
Crossref
Crossref
Wesam Al-Amarat, Mohammad H. Abukhalil, Reem S. Alruhaimi, Haifa A. Alqhtani, Nouf Aldawood, Manal A. Alfwuaires, Osama Y. Althunibat, Saleem H. Aladaileh, Abdulmohsen I. Algefare, Abdulkareem A. Alanezi, Ali M. AbouEl-ezz, Ahmad F. Ahmeda & Ayman M. Mahmoud. (2022) Upregulation of Nrf2/HO-1 Signaling and Attenuation of Oxidative Stress, Inflammation, and Cell Death Mediate the Protective Effect of Apigenin against Cyclophosphamide Hepatotoxicity. Metabolites 12:7, pages 648.
Crossref
Crossref
Giuseppe Caruso, Anna Privitera, Barbara Moura Antunes, Giuseppe Lazzarino, Susan Marie Lunte, Giancarlo Aldini & Filippo Caraci. (2022) The Therapeutic Potential of Carnosine as an Antidote against Drug-Induced Cardiotoxicity and Neurotoxicity: Focus on Nrf2 Pathway. Molecules 27:14, pages 4452.
Crossref
Crossref
Osama Y. Althunibat, Maisa Siddiq Abduh, Mohammad H. Abukhalil, Saleem H. Aladaileh, Hamza Hanieh & Ayman M. Mahmoud. (2022) Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats. Biomedicine & Pharmacotherapy 149, pages 112900.
Crossref
Crossref
Nancy S. Younis. (2022) β-Caryophyllene Ameliorates Cyclophosphamide Induced Cardiac Injury: The Association of TLR4/NFκB and Nrf2/HO1/NQO1 Pathways. Journal of Cardiovascular Development and Disease 9:5, pages 133.
Crossref
Crossref
Andrea RampinMichele CarrabbaMartina MutoliCharlotte L. EmanGianluca TestaPaolo MadedduGaia Spinetti. (2022)
Recent Advances in
KEAP1/NRF2
-Targeting Strategies by Phytochemical Antioxidants, Nanoparticles, and Biocompatible Scaffolds for the Treatment of Diabetic Cardiovascular Complications
. Antioxidants & Redox Signaling 36:10-12, pages 707-728.
Crossref
Crossref
Somow S. Kamel, Naiyra A. Abdel Baky, Riham M. Karkeet, Abdel‐Moneim M. Osman, Mohamed M. Sayed‐Ahmed & Mariam A. Fouad. (2021) Astaxanthin extenuates the inhibition of aldehyde dehydrogenase and Klotho protein expression in cyclophosphamide‐induced acute cardiomyopathic rat model. Clinical and Experimental Pharmacology and Physiology 49:2, pages 291-301.
Crossref
Crossref
Marwa MM Refaie, Maram El-Hussieny, Asmaa MA Bayoumi, Sayed Shehata, Nermeen N Welson & Walaa Yehia Abdelzaher. (2022) Simvastatin cardioprotection in cyclophosphamide-induced toxicity via the modulation of inflammasome/caspase1/interleukin1β pathway. Human & Experimental Toxicology 41, pages 096032712211114.
Crossref
Crossref
Omnia A. M. Abd El‐Ghafar, Emad H. M. Hassanein, Fares E. M. Ali, Zainab M. M. Omar, Eman K. Rashwan, Zuhair M. Mohammedsaleh & Ahmed M. Sayed. (2021)
Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/
ARE
,
IL6
/
STAT
‐3, and
NF‐κB
/
AP
‐1 signaling pathways
. Phytotherapy Research 36:1, pages 488-505.
Crossref
Crossref
Shankun Zhao, Peng Li, Weizhou Wu, Qinzhang Wang, Biao Qian, Xin Li & Maolei Shen. (2021) Roles of ferroptosis in urologic malignancies. Cancer Cell International 21:1.
Crossref
Crossref
Ahmed M. Sayed, Emad H.M. Hassanein, Fares E.M. Ali, Zainab M.M. Omar, Eman K. Rashwan, Zuhair M. Mohammedsaleh & Omnia A.M. Abd El-Ghafar. (2021) Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis. Life Sciences 284, pages 119911.
Crossref
Crossref
Emilia Zgorzynska, Barbara Dziedzic & Anna Walczewska. (2021) An Overview of the Nrf2/ARE Pathway and Its Role in Neurodegenerative Diseases. International Journal of Molecular Sciences 22:17, pages 9592.
Crossref
Crossref
Wedad S. Sarawi, Ahlam M. Alhusaini, Laila M. Fadda, Hatun A. Alomar, Awatif B. Albaker, Amjad S. Aljrboa, Areej M. Alotaibi, Iman H. Hasan & Ayman M. Mahmoud. (2021) Nano-Curcumin Prevents Cardiac Injury, Oxidative Stress and Inflammation, and Modulates TLR4/NF-κB and MAPK Signaling in Copper Sulfate-Intoxicated Rats. Antioxidants 10:9, pages 1414.
Crossref
Crossref
Khaled R.A. Abdellatif, Eman K.A. Abdelall, Heba A.H. Elshemy, John N. Philoppes, Emad H.M. Hassanein & Nesma M. Kahk. (2021) Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies. Bioorganic Chemistry 114, pages 105122.
Crossref
Crossref
Bertan B. Bayrak, Sebahat Yilmaz, Neziha Hacihasanoglu Cakmak & Refiye Yanardag. (2021) The effects of edaravone, a free‐radical scavenger in lung injury induced by valproic acid demonstrated via different biochemical parameters. Journal of Biochemical and Molecular Toxicology 35:9.
Crossref
Crossref