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Drug Design, Development and Therapy Volume 15, 2021 - Issue
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Review

Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin – A Promising Natural Lead for New Drug Discovery and Development

Nur Sakinah Muhamad Fadzil1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, Perak, MalaysiaView further author information
,
Mahendran Sekar1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, Perak, MalaysiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3022-6137View further author information
ORCID Icon,
Siew Hua Gan2 School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, MalaysiaORCID Iconhttps://orcid.org/0000-0001-6470-3651View further author information
ORCID Icon,
Srinivasa Reddy Bonam3 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Sorbonne Université, Université de Paris, Paris, FranceORCID Iconhttps://orcid.org/0000-0002-2888-2418View further author information
ORCID Icon,
Yuan Seng Wu4 Department of Biochemistry, School of Medicine, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra, Selangor, MalaysiaView further author information
,
Jaishree Vaijanathappa5 Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru, Karnataka, IndiaView further author information
,
Subban Ravi6 Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, IndiaView further author information
,
Pei Teng Lum1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, Perak, MalaysiaView further author information
&
Shivsharan B Dhadde7 D.S.T.S. Mandal’s College of Pharmacy, Solapur, Maharashtra, IndiaView further author information
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Pages 2721-2746 | Published online: 21 Jun 2021

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Ashutosh Goswami, Bhakti Nanaware & Abhijeet S. Kate. (2023) Rapid and Efficient SpPRE Approach: A Step Towards Meeting High Demand of Bioactive Swertiamarin. Separation Science and Technology 58:9, pages 1607-1615.
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Yaoyao Kou, Zhihao Li, Tong Yang, Xue Shen, Xin Wang, Haopeng Li, Kun Zhou, Luyao Li, Zhaodi Xia, Xiaohui Zheng & Ye Zhao. (2022) Therapeutic potential of plant iridoids in depression: a review. Pharmaceutical Biology 60:1, pages 2167-2181.
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Samar F. Darwish, Abdullah M. M. Elbadry, Amir S. Elbokhomy, Ghidaa A. Salama & Rania M. Salama. (2023) The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases. Frontiers in Aging 4.
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Tao Wang, Shubin Wu, Ibrahim Abdel Aziz Ibrahim & Leilei Fan. (2022) Cardioprotective Role of Swertiamarin, a Plant Glycoside Against Experimentally Induced Myocardial Infarction via Antioxidant and Anti-inflammatory Functions. Applied Biochemistry and Biotechnology 195:9, pages 5394-5408.
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Sa Guo, Qinyun Du, Nan Xing, Jing Qin, Xinwei Liu, Rui Li, Shaohui Wang & Yi Zhang. (2023) Swertia L.: A comprehensive review of its genetic relationship, chemical compositions, pharmacological effects, toxicities, and applications . Phytotherapy Research 37:6, pages 2605-2643.
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Sonam Sharma. (2023) Pharmacological mechanism of indigenous herb Exacum lawii on cisplatin instigated toxicity in human embryonic kidney cells (HEK-293). Phytomedicine Plus 3:2, pages 100454.
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Km Swati, Vinod Bhatt, Nitisha Sendri, Pooja Bhatt & Pamita Bhandari. (2023) Swertia chirayita: A comprehensive review on traditional uses, phytochemistry, quality assessment and pharmacology. Journal of Ethnopharmacology 300, pages 115714.
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