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Review

New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast

Andrew C PalfreemanThe Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, London, UKCorrespondence[email protected]
,
Kay E McNameeThe Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, London, UK
&
Fiona E McCannThe Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, London, UK
Pages 201-210 | Published online: 27 Mar 2013

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Yael Renert-Yuval & Emma Guttman-Yassky. (2016) A novel therapeutic paradigm for patients with extensive alopecia areata. Expert Opinion on Biological Therapy 16:8, pages 1005-1014.
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Maeve Lynch, Brian Kirby & Richard B Warren. (2014) Treating moderate to severe psoriasis – best use of biologics. Expert Review of Clinical Immunology 10:2, pages 269-279.
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Yanjie Fu, Xiuyan Li, Yuanzheng Chen, Rongpeng Liu, Renheng Wang & Nan Bai. (2018) Association of ERAP1 gene polymorphisms with the susceptibility to psoriasis vulgaris. Medicine 97:41, pages e12828.
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Liu Liu, Shunping Li, Yue Zhao, Jianglin Zhang & Gang Chen. (2018) Health state utilities and subjective well-being among psoriasis vulgaris patients in mainland China. Quality of Life Research 27:5, pages 1323-1333.
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Fernando Valenzuela, Javier Fernández & Pablo Santa María. (2018) Update on Oral Therapy for Psoriasis. Current Dermatology Reports 7:1, pages 52-58.
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Yael Renert-Yuval & Emma Guttman-Yassky. (2017) Systemic therapies in atopic dermatitis: The pipeline. Clinics in Dermatology 35:4, pages 387-397.
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Yael Renert-Yuval & Emma Guttman-Yassky. (2017) The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm. Advances in Therapy 34:7, pages 1594-1609.
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Ilaria Ruffilli, Francesca Ragusa, Salvatore Benvenga, Roberto Vita, Alessandro Antonelli, Poupak Fallahi & Silvia Martina Ferrari. (2017) Psoriasis, Psoriatic Arthritis, and Thyroid Autoimmunity. Frontiers in Endocrinology 8.
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Klaus Rose & Rudolf Happle. (2017) The Effect of Regulation on Pediatric Psoriasis Drug Approvals: The Challenge of the European Union Pediatric Investigation Plans. Pediatric Dermatology 34:3, pages e154-e159.
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Aditya K. Gupta, Jessie Carviel & William Abramovits. (2016) Treating Alopecia Areata: Current Practices Versus New Directions. American Journal of Clinical Dermatology 18:1, pages 67-75.
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Tae-Hoon Shin, Hyung-Sik Kim, Soon Choi & Kyung-Sun Kang. (2017) Mesenchymal Stem Cell Therapy for Inflammatory Skin Diseases: Clinical Potential and Mode of Action. International Journal of Molecular Sciences 18:2, pages 244.
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Vibeke Strand, Elaine Husni, Jenny Griffith, Zheng-Yi Zhou, James Signorovitch & Arijit Ganguli. (2016) Economic Evaluation of Timely Versus Delayed Use of Tumor Necrosis Factor Inhibitors for Treatment of Psoriatic Arthritis in the US. Rheumatology and Therapy 3:2, pages 305-322.
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Natalia V Zamora, Ignacio-Alfredo Valerio-Morales, Maria Angeles Lopez-Olivo, Xin Pan & Maria E Suarez-Almazor. (2016) Phosphodiesterase 4 inhibitors for psoriatic arthritis. Cochrane Database of Systematic Reviews.
Crossref
Fu-Jun Tian, Ying-Ying Zhang, Li-Qian Liu, Ying Xiong, Zong-Shan Wang & Shou-Zhong Wang. (2016) Haptoglobin protein and mRNA expression in psoriasis and its clinical significance. Molecular Medicine Reports 14:4, pages 3735-3742.
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Lian-guo Chen, Zhe Wang, Shujun Wang, Tao Li, Yongyang Pan & Xixi Lai. (2016) Determination of Apremilast in Rat Plasma by UPLC–MS-MS and Its Application to a Pharmacokinetic Study. Journal of Chromatographic Science 54:8, pages 1336-1340.
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Neha Arora, Kavita Shah & Shashi Pandey-Rai. (2015) Inhibition of imiquimod-induced psoriasis-like dermatitis in mice by herbal extracts from some Indian medicinal plants. Protoplasma 253:2, pages 503-515.
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S. V. Smirnova, M. V. Smolnikova & A. A. Barilo. (2016) Clinical and anamnestic criteria of the progression of psoriasis. Klinicheskaya dermatologiya i venerologiya 15:2, pages 9.
Crossref
Hassaan Tohid, Daniyal Aleem & Chantal Jackson. (2016) Major Depression and Psoriasis: A Psychodermatological Phenomenon. Skin Pharmacology and Physiology 29:4, pages 220-230.
Crossref
Garry G. Graham & Kevin D. Pile. 2016. Compendium of Inflammatory Diseases. Compendium of Inflammatory Diseases 1079 1084 .
Carl Orr & Douglas James Veale. (2015) Therapeutic targets in psoriatic arthritis. International Journal of Clinical Rheumatology 10:6, pages 489-499.
Crossref
Marieke Mohr, Kurt S. Zänker & Thomas Dittmar. (2015) Cancer (stem) cell differentiation: An inherent or acquired property?. Medical Hypotheses 85:6, pages 1012-1018.
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T. Lotti. (2015) Erfolgreiche Kombinationsbehandlung der Psoriasis mit Phototherapie und niedrig dosierten ZytokinenSuccessful combination treatment for psoriasis with phototherapy and low-dose cytokines. Der Hautarzt 66:11, pages 849-854.
Crossref
. (2015) ▼ Apremilast for psoriasis and psoriatic arthritis. Drug and Therapeutics Bulletin 53:9, pages 105-108.
Crossref
Silvia Martina Ferrari, Ilaria Ruffilli, Michele Colaci, Alessandro Antonelli, Clodoveo Ferri & Poupak Fallahi. (2015) CXCL10 in psoriasis. Advances in Medical Sciences 60:2, pages 349-354.
Crossref
Tiago Torres & Paulo Filipe. (2015) Small Molecules in the Treatment of Psoriasis. Drug Development Research 76:5, pages 215-227.
Crossref
Eun Jin Kang & Arthur Kavanaugh. (2015) Psoriatic arthritis: latest treatments and their place in therapy. Therapeutic Advances in Chronic Disease 6:4, pages 194-203.
Crossref
Kay McNamee, Richard Williams & Michael Seed. (2015) Animal models of rheumatoid arthritis: How informative are they?. European Journal of Pharmacology 759, pages 278-286.
Crossref
Irina Ushach, Amanda M. Burkhardt, Cynthia Martinez, Peter A. Hevezi, Peter Arne Gerber, Bettina Alexandra Buhren, Holger Schrumpf, Ricardo Valle-Rios, Monica I. Vazquez, Bernhard Homey & Albert Zlotnik. (2015) METEORIN-LIKE is a cytokine associated with barrier tissues and alternatively activated macrophages. Clinical Immunology 156:2, pages 119-127.
Crossref
Garry G. Graham & Kevin D. Pile. 2016. Encyclopedia of Inflammatory Diseases. Encyclopedia of Inflammatory Diseases 1 6 .
Carlo Selmi, Elena Generali, Marco Massarotti, Gerolamo Bianchi & Carlo A. Sciré. (2014) New treatments for inflammatory rheumatic disease. Immunologic Research 60:2-3, pages 277-288.
Crossref
Ana Susunaga-Notario, Salud Pérez-Gutiérrez, Miguel Zavala-Sánchez, Julio Almanza-Pérez, Atilano Gutiérrez-Carrillo, Daniel Arrieta-Báez, Ana López-López, Rubén Román-Ramos, José Flores-Sáenz & Francisco Alarcón-Aguilar. (2014) Bioassay-Guided Chemical Study of the Anti-Inflammatory Effect of Senna villosa (Miller) H.S. Irwin & Barneby (Leguminosae) in TPA-Induced Ear Edema. Molecules 19:7, pages 10261-10278.
Crossref
Sowmya Varada. (2018) Abatacept in Psoriatic Arthritis: A Review. Psoriasis Forum 20a:2, pages 60-65.
Crossref
Vincenzo Bruner, Mariangela Atteno, Angelo Spanò, Raffaele Scarpa & Rosario Peluso. (2014) Biological therapies for spondyloarthritis. Therapeutic Advances in Musculoskeletal Disease 6:3, pages 92-101.
Crossref
Medhi Moezzi, Andrea Ferencz & Dénes Lőrinczy. (2013) Evaluation of blood plasma changes by differential scanning calorimetry in psoriatic patients treated with drugs. Journal of Thermal Analysis and Calorimetry 116:2, pages 557-562.
Crossref
Arif Aslam & Christopher EM Griffiths. (2014) Drug therapies in dermatology. Clinical Medicine 14:1, pages 47-53.
Crossref
Jung-Tai Liu. (2014) Psoriatic arthritis: Epidemiology, diagnosis, and treatment. World Journal of Orthopedics 5:4, pages 537.
Crossref

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