In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models

Sarah Schleiferböck1 Swiss Tropical and Public Health Institute, Basel, Switzerland;2 University of Basel, Basel, Switzerland

Christian Scheurer1 Swiss Tropical and Public Health Institute, Basel, Switzerland;2 University of Basel, Basel, Switzerland

Masataka Ihara3 Drug Discovery Science Research Center, Hoshi University, Shinagawa, Tokyo, Japan;4 Synstar Japan Co, Ltd, Odawara, Japan

Isamu Itoh3 Drug Discovery Science Research Center, Hoshi University, Shinagawa, Tokyo, Japan;4 Synstar Japan Co, Ltd, Odawara, Japan

Ian Bathurst5 Medicines for Malaria Venture, Geneva, Switzerland

Jeremy N Burrows5 Medicines for Malaria Venture, Geneva, Switzerland

Pascal Fantauzzi5 Medicines for Malaria Venture, Geneva, Switzerland

Julie Lotharius5 Medicines for Malaria Venture, Geneva, Switzerland

Susan A Charman6 Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Parkville, VIC, Australia

Julia Morizzi6 Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Parkville, VIC, Australia

David M Shackleford6 Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Parkville, VIC, Australia

Karen L White6 Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Parkville, VIC, Australia

Reto Brun1 Swiss Tropical and Public Health Institute, Basel, Switzerland;2 University of Basel, Basel, Switzerland

Sergio Wittlin1 Swiss Tropical and Public Health Institute, Basel, Switzerland;2 University of Basel, Basel, SwitzerlandCorrespondence[email protected]

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In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models

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In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models

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