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Commentary

Profile of pridopidine and its potential in the treatment of Huntington disease: the evidence to date

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Pages 5827-5833 | Published online: 28 Oct 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

E. Unti, S. Mazzucchi, G. Palermo, U. Bonuccelli & R. Ceravolo. (2017) Antipsychotic drugs in Huntington’s disease. Expert Review of Neurotherapeutics 17:3, pages 227-237.
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Thomas Müller. (2017) Investigational agents for the management of Huntington’s disease. Expert Opinion on Investigational Drugs 26:2, pages 175-185.
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Articles from other publishers (14)

Ferenc Bogár, Lívia Fülöp & Botond Penke. (2022) Novel Therapeutic Target for Prevention of Neurodegenerative Diseases: Modulation of Neuroinflammation with Sig-1R Ligands. Biomolecules 12:3, pages 363.
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Michal Geva, Noga Gershoni-Emek, Luana Naia, Philip Ly, Sandra Mota, Ana Cristina Rego, Michael R. Hayden & Leonard A. Levin. (2021) Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma. Scientific Reports 11:1.
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Shujun Chen, Tianyu Liang, Tao Xue, Shouru Xue & Qun Xue. (2021) Pridopidine for the Improvement of Motor Function in Patients With Huntington's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Neurology 12.
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Magdalena Jabłońska, Klaudyna Grzelakowska, Bartłomiej Wiśniewski, Ewelina Mazur, Kamil Leis & Przemysław Gałązka. (2020) Pridopidine in the treatment of Huntington’s disease. Reviews in the Neurosciences 31:4, pages 441-451.
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Talya Shacham, Neeraj Sharma & Gerardo Z. Lederkremer. (2019) Protein Misfolding and ER Stress in Huntington's Disease. Frontiers in Molecular Biosciences 6.
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Katya T Potkin & Steven G Potkin. (2018) New directions in therapeutics for Huntington disease. Future Neurology 13:2, pages 101-121.
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Isha Monga, Abid Qureshi, Nishant Thakur, Amit Kumar Gupta & Manoj Kumar. (2017) ASPsiRNA: A Resource of ASP-siRNAs Having Therapeutic Potential for Human Genetic Disorders and Algorithm for Prediction of Their Inhibitory Efficacy. G3 Genes|Genomes|Genetics 7:9, pages 2931-2943.
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Cristina Sánchez-Castañeda, Francesco de Pasquale, Chiara Falletta Caravasso, Massimo Marano, Sabrina Maffi, Simone Migliore, Umberto Sabatini & Ferdinando Squitieri. (2017) Resting-state connectivity and modulated somatomotor and default-mode networks in Huntington disease. CNS Neuroscience & Therapeutics 23:6, pages 488-497.
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Abhijit Dey. 2017. Neuroprotective Natural Products. Neuroprotective Natural Products 185 246 .
Emma M. Coppen & Raymund A. C. Roos. (2016) Current Pharmacological Approaches to Reduce Chorea in Huntington’s Disease. Drugs 77:1, pages 29-46.
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Claudia Rangel-Barajas & George V. Rebec. (2016) Dysregulation of Corticostriatal Connectivity in Huntington’s Disease: A Role for Dopamine Modulation. Journal of Huntington's Disease 5:4, pages 303-331.
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Qinqin Wang, Qinbo Zhou, Shuzhen Zhang, Wei Shao, Yanqing Yin, Yandong Li, Jincan Hou, Xinhua Zhang, Yongshun Guo, Xiaomin Wang, Xiaosong Gu & Jiawei Zhou. (2016) Elevated Hapln2 Expression Contributes to Protein Aggregation and Neurodegeneration in an Animal Model of Parkinson's Disease. Frontiers in Aging Neuroscience 8.
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Abhishek Chandra, Abhijeet Sharma, Noel Y. Calingasan, Joshua M. White, Yevgeniya Shurubor, X. William Yang, M. Flint Beal & Ashu Johri. (2016) Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington’s disease. Human Molecular Genetics 25:11, pages 2269-2282.
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Tsung-Ping Su, Tzu-Chieh Su, Yoki Nakamura & Shang-Yi Tsai. (2016) The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems. Trends in Pharmacological Sciences 37:4, pages 262-278.
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