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Drug Design, Development and Therapy Volume 8, 2014 - Issue
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Original Research

Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters

Chika Saigo1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
,
Yui Nomura1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
,
Yuko Yamamoto1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
,
Masataka Sagata1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
,
Rika Matsunaga1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
,
Hirofumi Jono1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan;2 Department of Pharmacy, Kumamoto University Hospital, Kumamoto, Japan
,
Kazuhiko Nishi3 Department of Hemo-Dialysis, Kumamoto University Hospital, Kumamoto, Japan
&
Hideyuki Saito1 Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan;2 Department of Pharmacy, Kumamoto University Hospital, Kumamoto, JapanCorrespondence[email protected]
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Pages 1073-1082 | Published online: 13 Aug 2014

Citations (5)

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Read on this site (1)

Alexander J Prokopienko & Thomas D Nolin. (2018) Microbiota-derived uremic retention solutes: perpetrators of altered nonrenal drug clearance in kidney disease. Expert Review of Clinical Pharmacology 11:1, pages 71-82.
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Articles from other publishers (4)

Jia-Huang Chen & Chih-Kang Chiang. (2021) Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence. Toxins 14:1, pages 8.
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Ping-Hsun Lu, Min-Chien Yu, Meng-Jiun Wei & Ko-Lin Kuo. (2021) The Therapeutic Strategies for Uremic Toxins Control in Chronic Kidney Disease. Toxins 13:8, pages 573.
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Nozomi Yabuuchi, Huixian Hou, Nao Gunda, Yuki Narita, Hirofumi Jono & Hideyuki Saito. (2021) Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice. International Journal of Molecular Sciences 22:4, pages 1764.
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Esmeralda Castillo-Rodriguez, Raul Fernandez-Prado, Raquel Esteras, Maria Perez-Gomez, Carolina Gracia-Iguacel, Beatriz Fernandez-Fernandez, Mehmet Kanbay, Alberto Tejedor, Alberto Lazaro, Marta Ruiz-Ortega, Emilio Gonzalez-Parra, Ana Sanz, Alberto Ortiz & Maria Sanchez-Niño. (2018) Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression. Toxins 10:7, pages 300.
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