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Review

Profile of netupitant/palonosetron (NEPA) fixed dose combination and its potential in the treatment of chemotherapy-induced nausea and vomiting (CINV)

Pages 155-161 | Published online: 17 Dec 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Rudolph M Navari. (2019) The safety of rolapitant for the treatment of nausea and vomiting associated with chemotherapy. Expert Opinion on Drug Safety 18:12, pages 1127-1132.
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Rudolph M Navari. (2017) Cancer patients at high risk for chemotherapy-induced nausea and vomiting – prediction assessments/tools. Expert Review of Quality of Life in Cancer Care 2:2, pages 103-108.
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Piotr K Janicki. (2016) Management of acute and delayed chemotherapy-induced nausea and vomiting: role of netupitant–palonosetron combination. Therapeutics and Clinical Risk Management 12, pages 693-699.
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Rudolph M. Navari. (2016) The safety of antiemetic medications for the prevention of chemotherapy-induced nausea and vomiting. Expert Opinion on Drug Safety 15:3, pages 343-356.
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Rudolph M Navari. (2015) Rolapitant for the treatment of chemotherapy-induced nausea and vomiting. Expert Review of Anticancer Therapy 15:10, pages 1127-1133.
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Articles from other publishers (7)

Bharat Vaswani, Palanki Satya Dattatreya, Sagar Bhagat, Saiprasad Patil & Hanmant Barkate. (2021) The effectiveness of NEPA in the prevention of chemotherapy-induced nausea vomiting among chemo naive patients in an Indian setting. BMC Cancer 21:1.
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Marc Botteman, Katharina Nickel, Shelby Corman, Marco Turini & Gary Binder. (2019) Cost-effectiveness of a fixed combination of netupitant and palonosetron (NEPA) relative to aprepitant plus granisetron (APR + GRAN) for prophylaxis of chemotherapy-induced nausea and vomiting (CINV): a trial-based analysis. Supportive Care in Cancer 28:2, pages 857-866.
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R. Ienca, C. Giardiello, A. Scozzarro, R. Schiano di Cola, N. Di Lorenzo, Girish Juneja, G. Lopez & F. Badiuddin. (2019) Improving Nausea and Vomiting Post-Elipse Balloon: a Novel Single-Dose Regimen of 300 mg Netupitant/0.5 mg Palonosetron Hydrochloride. Obesity Surgery 29:9, pages 2952-2956.
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James Gilmore & Alberto Bernareggi. (2019) Complementary Pharmacokinetic Profiles of Netupitant and Palonosetron Support the Rationale for Their Oral Fixed Combination for the Prevention of Chemotherapy-Induced Nausea and Vomiting. The Journal of Clinical Pharmacology 59:4, pages 472-487.
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John A. Rudd, Sze W. Chan, Man P. Ngan, Longlong Tu, Zengbing Lu, Claudio Giuliano, Emanuela Lovati & Claudio Pietra. (2018) Anti-emetic Action of the Brain-Penetrating New Ghrelin Agonist, HM01, Alone and in Combination With the 5-HT3 Antagonist, Palonosetron and With the NK1 Antagonist, Netupitant, Against Cisplatin- and Motion-Induced Emesis in Suncus murinus (House Musk Shrew). Frontiers in Pharmacology 9.
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John A. Rudd, Man P. Ngan, Zengbing Lu, Guy A. Higgins, Claudio Giuliano, Emanuela Lovati & Claudio Pietra. (2016) Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew). Frontiers in Pharmacology 7.
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Yu Zhou, Jiang Wang, Zhanni Gu, Shuni Wang, Wei Zhu, José Luis Aceña, Vadim A. Soloshonok, Kunisuke Izawa & Hong Liu. (2016) Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas. Chemical Reviews 116:2, pages 422-518.
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