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Drug Design, Development and Therapy Volume 9, 2015 - Issue
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Original Research

A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects

Jin Ah Jung1 Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Sungkyunkwan University, Seoul, Kore
,
Soo-Yun Lee2 Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
,
Jung-Ryul Kim1 Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Sungkyunkwan University, Seoul, Kore
,
Jae-Wook Ko1 Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Sungkyunkwan University, Seoul, Kore;2 Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea
,
Seong Bok Jang3 Yuhan Research Institute, Yuhan Corporation, Sungkyunkwan University School of Medicine, Seoul, Korea
,
Su Youn Nam3 Yuhan Research Institute, Yuhan Corporation, Sungkyunkwan University School of Medicine, Seoul, Korea
&
Wooseong Huh1 Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Sungkyunkwan University, Seoul, Kore;4 Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaCorrespondence[email protected]
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Pages 745-752 | Published online: 02 Mar 2015

Citations (10)

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Read on this site (2)

Yang Liu, Jiaqi Zhang, Di Wu & Liran Cui. (2020) Pharmacokinetic interaction study between ligustrazine and valsartan in rats and its potential mechanism. Pharmaceutical Biology 58:1, pages 1299-1302.
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Yewon Choi, SeungHwan Lee, In-Jin Jang & Kyung-Sang Yu. (2018) Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers. Drug Design, Development and Therapy 12, pages 2301-2309.
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Articles from other publishers (8)

Yunzhe Huang, Ran Liu, Yaqin Wang, Gege Liu, Changmao Wang, Xinyan Chen, Yuanwei Jia & Jie Shen. (2022) Evaluation of Pharmacokinetic Interactions Between the New SGLT2 Inhibitor SHR3824 and Valsartan in Healthy Chinese Volunteers. Clinical Therapeutics 44:7, pages 945-956.
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Raju Kanukula, Abdul Salam, Anthony Rodgers & Bishoy Kamel. (2021) Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults. Clinical Pharmacokinetics 60:2, pages 165-175.
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Eline H. GroenlandMonique E.A.M. van KleefMichiel L. BotsFrank L.J. Visseren, Kim C.M. van der ElstWilko Spiering. (2021) Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence. Hypertension 77:1, pages 85-93.
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Sook Jin Seong, Boram Ohk, Woo Youl Kang, Mi-Ri Gwon, Bo Kyung Kim, Seungil Cho, Dong Heon Yang, Hae Won Lee & Young-Ran Yoon. (2019) Pharmacokinetic Drug Interactions Between Amlodipine, Valsartan, and Rosuvastatin in Healthy Volunteers. Advances in Therapy 36:7, pages 1642-1656.
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Aimei Liu, Qinghua Wu, Jingchao Guo, Irma Ares, José-Luis Rodríguez, María-Rosa Martínez-Larrañaga, Zonghui Yuan, Arturo Anadón, Xu Wang & María-Aránzazu Martínez. (2019) Statins: Adverse reactions, oxidative stress and metabolic interactions. Pharmacology & Therapeutics 195, pages 54-84.
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Na Liu, Guihua Yang, Mei Hu, Yuyu Cai, Zhiying Hu, Chundi Jia & Man Zhang. (2018) Association of ABCC2   polymorphism and gender with high-density lipoprotein cholesterol response to simvastatin . Pharmacogenomics 19:14, pages 1125-1132.
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Miao Hu, Hon-Kit Lee, Kenneth K. W. To, Benny S. P. Fok, Siu-Kwan Wo, Chung-Shun Ho, Chun-Kwok Wong, Zhong Zuo, Thomas Y. K. Chan, Juliana C. N. Chan & Brian Tomlinson. (2016) Telmisartan increases systemic exposure to rosuvastatin after single and multiple doses, and in vitro studies show telmisartan inhibits ABCG2-mediated transport of rosuvastatin. European Journal of Clinical Pharmacology 72:12, pages 1471-1478.
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Shotaro Sasaki, Yuya Futagi, Masaya Ideno, Masaki Kobayashi, Katsuya Narumi, Ayako Furugen & Ken Iseki. (2016) Interaction of atorvastatin with the human glial transporter SLC16A1. European Journal of Pharmacology 788, pages 248-254.
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