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Drug Design, Development and Therapy Volume 9, 2015 - Issue
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Original Research

Cissus quadrangularis inhibits IL-1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling

Jagat R Kanwar1 Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR) Strategic Research Centre, Faculty of Health, Geelong Technology Precinct (GTP), Deakin University, Waurn Ponds, VIC, Australia
,
Rasika M Samarasinghe1 Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR) Strategic Research Centre, Faculty of Health, Geelong Technology Precinct (GTP), Deakin University, Waurn Ponds, VIC, Australia
,
Kuldeep Kumar2 Ayurvedic College, Paprola, Kangra, Himachal Pradesh, India
,
Ramesh Arya2 Ayurvedic College, Paprola, Kangra, Himachal Pradesh, India
,
Sanjeev Sharma2 Ayurvedic College, Paprola, Kangra, Himachal Pradesh, India
,
Shu-Feng Zhou3 Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA
,
Sreenivasan Sasidharan4 Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, Malaysia
&
Rupinder K Kanwar1 Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR) Strategic Research Centre, Faculty of Health, Geelong Technology Precinct (GTP), Deakin University, Waurn Ponds, VIC, AustraliaCorrespondence[email protected]
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Pages 2927-2940 | Published online: 05 Jun 2015

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Mallikarjuna Nimgampalle, Hemanth Naick Banavath, Harshini Chakravarthy, Ambrish Saxena & Vasudharani Devanathan. (2020) Novel inhibitors of Rho-kinase mediated neuroinflammatory pathways and their potential application in recovery of injured spinal cord. Journal of Biomolecular Structure and Dynamics 38:16, pages 4669-4686.
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Articles from other publishers (13)

Jin A Yoon, Tae-Hwan Jung, Hyo-Jeong Hwang, Il-Ho Park & Kyung-Ok Shin. (2023) Physiological Activity and Function of Cissus quadrangularis. Journal of the East Asian Society of Dietary Life 33:2, pages 105-114.
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Kenny Kuchta & Silke Cameron. (2021) Tradition to Pathogenesis: A Novel Hypothesis for Elucidating the Pathogenesis of Diseases Based on the Traditional Use of Medicinal Plants. Frontiers in Pharmacology 12.
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Piyush S. Bafna, Payal H. Patil, Saurabh K. Maru & Rakesh E. Mutha. (2021) Cissus quadrangularis L: A comprehensive multidisciplinary review. Journal of Ethnopharmacology 279, pages 114355.
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Chun-Na Lan, Wei-Jun Cai, Jie Shi & Zhong-Jie Yi. (2021) MAPK inhibitors protect against early‑stage osteoarthritis by activating autophagy. Molecular Medicine Reports 24:6.
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Woosuk Kim, Hyun Jung Kwon, Hyo Young Jung, Soon-Sung Lim, Beom-Goo Kang, Yong-Bok Jo, Dong-Sool Yu, Soo Young Choi, In Koo Hwang & Dae Won Kim. (2021) Cissus verticillata Extract Decreases Neuronal Damage Induced by Oxidative Stress in HT22 Cells and Ischemia in Gerbils by Reducing the Inflammation and Phosphorylation of MAPKs. Plants 10:6, pages 1217.
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Zaki Sadiya, Malathi R, Latha V & Sibi G. (2020) A review on efficacy of Cissus quadrangularis in pharmacological mechanisms. International Journal of Clinical Microbiology and Biochemical Technology 3:1, pages 049-053.
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Prerna Singh, Archita Gupta, Irfan Qayoom, Sneha Singh & Ashok Kumar. (2020) Orthobiologics with phytobioactive cues: A paradigm in bone regeneration. Biomedicine & Pharmacotherapy 130, pages 110754.
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Yuzhe He, Safwat Moqbel, Langhai Xu, Jisheng Ran, Chiyuan Ma, Kai Xu, Jiapeng Bao, Lifeng Jiang, Weiping Chen, Yan Xiong & Lidong Wu. (2019) Costunolide inhibits matrix metalloproteinases expression and osteoarthritis via the NF‑κB and Wnt/β‑catenin signaling pathways. Molecular Medicine Reports.
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Fereshteh Morrovati, Nahid Karimian Fathi, Jafar Soleimani Rad & Azadeh Montaseri. (2018) Mummy Prevents IL-1β-Induced Inflammatory Responses and Cartilage Matrix Degradation via Inhibition of NF-қB Subunits Gene Expression in Pellet Culture System. Advanced Pharmaceutical Bulletin 8:2, pages 283-289.
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C. D. Yu, W. H. Miao, Y. Y. Zhang, M. J. Zou & X. F. Yan. (2018) Inhibition of miR-126 protects chondrocytes from IL-1β induced inflammation via upregulation of Bcl-2. Bone & Joint Research 7:6, pages 414-421.
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Chun Zhang, Ling Yu, Yan Zhou, Qi Zhao & Shi-Qing Liu. (2016) Chitosan oligosaccharides inhibit IL-1β-induced chondrocyte apoptosis via the P38 MAPK signaling pathway. Glycoconjugate Journal 33:5, pages 735-744.
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Barbara D. Boyan, Sharon L. Hyzy, Qingfen Pan, Kayla M. Scott, Richard D. Coutts, Robert Healey & Zvi Schwartz. (2016) 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats. PLOS ONE 11:8, pages e0161782.
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Bo Hu, Changgui Shi, Chen Xu, Peng Cao, Ye Tian, Ying Zhang, Lianfu Deng, Huajiang Chen & Wen Yuan. (2016) Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration. Scientific Reports 6:1.
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