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Drug Design, Development and Therapy Volume 9, 2015 - Issue
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Original Research

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Yo Han Kim1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea
,
Hee Youn Choi1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea
,
Hyeong-Seok Lim1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea
,
Shi Hyang Lee1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea
,
Hae Sun Jeon1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea
,
Donghyun Hong2 iCure Pharmaceutical lncorporated, Anseong, Gyeonggi-do, Republic of Korea
,
Seong Su Kim2 iCure Pharmaceutical lncorporated, Anseong, Gyeonggi-do, Republic of Korea
,
Young Kweon Choi2 iCure Pharmaceutical lncorporated, Anseong, Gyeonggi-do, Republic of Korea
&
Kyun-Seop Bae1 Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of KoreaCorrespondence[email protected]
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Pages 1419-1426 | Published online: 10 Mar 2015

Citations (9)

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Read on this site (3)

Seok Kyu Yoon, Kyun-Seop Bae, Dong Hyun Hong, Seong Su Kim, Young Kweon Choi & Hyeong-Seok Lim. (2020) Pharmacokinetic Evaluation by Modeling and Simulation Analysis of a Donepezil Patch Formulation in Healthy Male Volunteers. Drug Design, Development and Therapy 14, pages 1729-1737.
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F. Zhang, M. Bartels, A. Clark, T. Erskine, T. Auernhammer, B. Bhhatarai, D. Wilson & S. Marty. (2018) Performance evaluation of the GastroPlusTM software tool for prediction of the toxicokinetic parameters of chemicals. SAR and QSAR in Environmental Research 29:11, pages 875-893.
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Kevin Ita. (2017) Recent trends in the transdermal delivery of therapeutic agents used for the management of neurodegenerative diseases. Journal of Drug Targeting 25:5, pages 406-419.
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Articles from other publishers (6)

Won Fen Wong, Kuan Ping Ang, Gautam Sethi & Chung Yeng Looi. (2023) Recent Advancement of Medical Patch for Transdermal Drug Delivery. Medicina 59:4, pages 778.
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Linh Dinh, Soohun Lee, Sharif Md Abuzar, Heejun Park & Sung-Joo Hwang. (2022) Formulation, Preparation, Characterization, and Evaluation of Dicarboxylic Ionic Liquid Donepezil Transdermal Patches. Pharmaceutics 14:1, pages 205.
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Hyun Jeong Han, Mee Young Park, Kyung Won Park, Kee Hyung Park, Seong Hye Choi, Hee-Jin Kim, Dong Won Yang, Esther Gunaseli Ebenezer, Yuan-Han Yang, Gurudev M. Kewalram & Seol-Heui Han. (2022) A Multinational, Multicenter, Randomized, Double-Blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer’s Disease. Journal of Clinical Neurology 18:4, pages 428.
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Ze Qiang Zhao, Bo Zhi Chen, Xiao Peng Zhang, Hui Zheng & Xin Dong Guo. (2021) An Update on the Routes for the Delivery of Donepezil. Molecular Pharmaceutics 18:7, pages 2482-2494.
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Archana S. Nayak, Srivani Chodisetti, Shivaprasad Gadag, Usha Yogendra Nayak, Srinikethan Govindan & Keyur Raval. (2020) Tailoring solulan C24 based niosomes for transdermal delivery of donepezil: In vitro characterization, evaluation of pH sensitivity, and microneedle-assisted Ex vivo permeation studies. Journal of Drug Delivery Science and Technology 60, pages 101945.
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Hee Youn Choi, Yo Han Kim, Donghyun Hong, Seong Su Kim, Kyun-Seop Bae & Hyeong-Seok Lim. (2015) Therapeutic dosage assessment based on population pharmacokinetics of a novel single-dose transdermal donepezil patch in healthy volunteers. European Journal of Clinical Pharmacology 71:8, pages 967-977.
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