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Original Research

Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase

Nagla A El-Shitany1 Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;2 Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, EgyptCorrespondence[email protected]

Karema El-Desoky3 Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt

Pages 5237-5246 | Published online: 16 Sep 2015

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Yiyi Ji, Bo Liu, Lei Chen, Ang Li, Kai Shen, Ruopeng Su, Weiwei Zhang, Yinjie Zhu, Qi Wang & Wei Xue. (2023) Repurposing ketotifen as a therapeutic strategy for neuroendocrine prostate cancer by targeting the IL-6/STAT3 pathway. Cellular Oncology.
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Yang Li, Annette Palmer, Ludmila Lupu & Markus Huber-Lang. (2022) Inflammatory response to the ischaemia–reperfusion insult in the liver after major tissue trauma. European Journal of Trauma and Emergency Surgery 48:6, pages 4431-4444.
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Nora Jahn, Ulrich Sack, Sebastian Stehr, Maria Theresa Vöelker, Sven Laudi, Daniel Seehofer, Selim Atay, Panagiota Zgoura, Richard Viebahn, Andreas Boldt & Hans-Michael Hau. (2022) The Role of Innate Immune Cells in the Prediction of Early Renal Allograft Injury Following Kidney Transplantation. Journal of Clinical Medicine 11:20, pages 6148.
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Richi Nakatake, Mareike Schulz, Christina Kalvelage, Carina Benstoem & René H. Tolba. (2022) Effects of iNOS in Hepatic Warm Ischaemia and Reperfusion Models in Mice and Rats: A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences 23:19, pages 11916.
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Deniz Ragipoglu, Jasmin Bülow, Kristin Hauff, Martin Voss, Melanie Haffner-Luntzer, Anne Dudeck, Anita Ignatius & Verena Fischer. (2022) Mast Cells Drive Systemic Inflammation and Compromised Bone Repair After Trauma. Frontiers in Immunology 13.
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Norbert Lukan. (2020) “Cytokine storm”, not only in COVID-19 patients. Mini-review. Immunology Letters 228, pages 38-44.
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Stephanie A. Legere, Ian D. Haidl, Jean-François Légaré & Jean S. Marshall. (2019) Mast Cells in Cardiac Fibrosis: New Insights Suggest Opportunities for Intervention. Frontiers in Immunology 10.
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Zhigang He, Cheng Ma, Tianyu Yu, Jian Song, Jing Leng, Xianbin Gu & Jiyu Li. (2019) Activation mechanisms and multifaceted effects of mast cells in ischemia reperfusion injury. Experimental Cell Research 376:2, pages 227-235.
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Natalie Chaves Cayuela, Gabrielly Pascoa Negreti, Roberto Rasslan, Marcia Kiyomi Koike & Edna Frasson de Souza Montero. (2018) Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepatic steatosis or steatohepatitis. Acta Cirurgica Brasileira 33:9, pages 753-761.
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Wei-An Mao, Yuan-Yuan Sun, Jing-Yi Mao, Li Wang, Jian Zhang, Jie Zhou, Khalid Rahman & Ying Ye. (2016) Inhibitory Effects of Angelica Polysaccharide on Activation of Mast Cells. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-10.
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Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase

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Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase

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