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Drug Design, Development and Therapy Volume 9, 2015 - Issue
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Original Research

Celecoxib coupled to dextran via a glutamic acid linker yields a polymeric prodrug suitable for colonic delivery

Yonghyun Lee1 College of Pharmacy, Pusan National University, Busan, Republic of Korea;2 Bio-Nanomedicine Laboratory, Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea
,
Jungyun Kim1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Wooseong Kim1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Joon Nam1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Seongkeun Jeong1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Sunyoung Lee1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Jin-Wook Yoo1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
,
Min-Soo Kim1 College of Pharmacy, Pusan National University, Busan, Republic of Korea
&
Yunjin Jung1 College of Pharmacy, Pusan National University, Busan, Republic of KoreaCorrespondence[email protected]
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Pages 4105-4113 | Published online: 30 Jul 2015

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Wooseong Kim, Yejin Yang, Dohoon Kim, Seongkeun Jeong, Jin-Wook Yoo, Jeong-Hyun Yoon & Yunjin Jung. (2017) Conjugation of metronidazole with dextran: a potential pharmaceutical strategy to control colonic distribution of the anti-amebic drug susceptible to metabolism by colonic microbes. Drug Design, Development and Therapy 11, pages 419-429.
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Articles from other publishers (2)

Diana K. Ghobrial, Nefertiti El-Nikhely, Eman Sheta, Hanan M. Ragab, Sherif A. F. Rostom, Hesham Saeed & Ahmed Wahid. (2023) The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl4-Induced Liver Fibrosis in Rats. Antioxidants 12:3, pages 637.
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Yonghyun Lee, Jungyun Kim, Wooseong Kim, In-Soo Yoon & Yunjin Jung. (2020) Preparation and Evaluation of Amino Acid Conjugates of Celecoxib as Prodrugs to Improve the Pharmacokinetic and Therapeutic Properties of Celecoxib. Pharmaceutics 12:11, pages 1043.
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