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Drug Design, Development and Therapy Volume 9, 2015 - Issue
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Original Research

Protective effects of alginate–chitosan microspheres loaded with alkaloids from Coptis chinensis Franch. and Evodia rutaecarpa (Juss.) Benth. (Zuojin Pill) against ethanol-induced acute gastric mucosal injury in rats

Qiang-Song Wang1 Tianjin State Key Laboratory of Modern Chinese Medicine, Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China;2 Institute of Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, People’s Republic of China
,
Xiao-Ning Zhu1 Tianjin State Key Laboratory of Modern Chinese Medicine, Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China
,
Heng-Li Jiang1 Tianjin State Key Laboratory of Modern Chinese Medicine, Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China
,
Gui-Fang Wang3 Pharmacy Department, Baokang Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China
&
Yuan-Lu Cui1 Tianjin State Key Laboratory of Modern Chinese Medicine, Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of ChinaCorrespondence[email protected]
Pages 6151-6165 | Published online: 19 Nov 2015

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Jiaying Zhang, Yi Yin, Qianqian Xu, Xiaoqing Che, Chen Yu, Yan Ren, Dongsheng Li & Juanjuan Zhao. (2022) Integrated serum pharmacochemistry and investigation of the anti-gastric ulcer effect of Zuojin pill in rats induced by ethanol. Pharmaceutical Biology 60:1, pages 1417-1435.
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Kaikai Bai, Bihong Hong, Ran Tan, Jianlin He & Zhuan Hong. (2020) Selenium Nanoparticles-Embedded Chitosan Microspheres and Their Effects Upon Alcohol-Induced Gastric Mucosal Injury in Rats: Rapid Preparation, Oral Delivery, and Gastroprotective Potential of Selenium Nanoparticles. International Journal of Nanomedicine 15, pages 1187-1203.
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Pandurang Appana Dalavi, Ashwini Prabhu, Rajesh P. Shastry & Jayachandran Venkatesan. (2020) Microspheres containing biosynthesized silver nanoparticles with alginate-nano hydroxyapatite for biomedical applications. Journal of Biomaterials Science, Polymer Edition 31:16, pages 2025-2043.
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Asmaa Aboul Naser, Eman Younis, Amal El-Feky, Marwa Elbatanony & Manal Hamed. (2020) Management of Citrus sinensis peels for protection and treatment against gastric ulcer induced by ethanol in rats. Biomarkers 25:4, pages 349-359.
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Articles from other publishers (6)

Sarita Garg, Rajeev K. Singla, Md. Mominur Rahman, Rohit Sharma & Vineet Mittal. (2022) Evaluation of Ulcer Protective Activity of Morus alba L. Extract-Loaded Chitosan Microspheres in Ethanol-Induced Ulcer in Rat Model. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-17.
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Leudimar Aires Pereira, Luizângela da Silva Reis, Anderson Nogueira Mendes, Hélio de Barros Fernandes, Daniel Dias Rufino Arcanjo, Adalberto Fortes Rodrigues Júnior, Janete Martins Sousa, Humberto Medeiros Barreto, Jailson de Araújo Santos, Josy Anteveli Osajima & Edson C. Silva Filho. (2022) Antiulcerogenic and Antibacterial Effects of Chitosan Derivatives on Experimental Gastric Ulcers in Rats. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-9.
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Lei Xie, Minyi Luo, Junlin Li, Wenguan Huang, Guangjun Tian, Xiuyun Chen, Ying Ai, Yan Zhang, Haolan He & Jinyang He. (2022) Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway. Frontiers in Pharmacology 13.
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Ruilin Wang, Yanling Wang, Zheng Lu, Jing Jing, Zhongxia Wang, Tingting He, Miao Tian, Zongyang Yuan, Yanfei Cui, Wenya Rong, Xiao Ma & Yanling Zhao. (2022) Efficacy and Safety of Zuojin Pill for the Treatment of Chronic Nonatrophic Gastritis: A Randomized Active-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-9.
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Maged Mohamed Abd-Elhaki, Noha Ahmed El-B, Ebtehal Kamal Eldi, Ataa Abdelhalim & Sylvia Edward Sha. (2019) Protective and Curative Effects of Bombax ceiba Flower and Ziziphus spina christi Fruit Extracts on Gastric Ulcer. Journal of Biological Sciences 19:2, pages 161-172.
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Anthony C. Johnson & Beverley Greenwood-Van Meerveld. 2017. Gastrointestinal Pharmacology. Gastrointestinal Pharmacology 289 317 .

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