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Diabetes, Metabolic Syndrome and Obesity Volume 12, 2019 - Issue
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Original Research

Jinmaitong Ameliorates Diabetic Peripheral Neuropathy Through Suppressing TXNIP/NLRP3 Inflammasome Activation In The Streptozotocin-Induced Diabetic Rat Model

Qing Sun1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China
,
Chao Wang1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China
,
Bin Yan1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China
,
Xiaohu Shi1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-7915-2207
ORCID Icon,
Yue Shi1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China
,
Ling Qu1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China
&
Xiaochun Liang1 Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of ChinaCorrespondence[email protected]
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Pages 2145-2155 | Published online: 17 Oct 2019

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Mohammed A. Attia, Nema Soliman, Mohamed Ahmed Eladl, Shymaa E. Bilasy, Taghrid B. El-Abaseri, Howaida S. Ali, Faten Abbas, Dalia Ibrahim, Noura M. S. Osman, Abdullah A. Hashish, Asma Alshahrani, Abir S. Mohamed & Sawsan A. Zaitone. (2023) Topiramate affords neuroprotection in diabetic neuropathy model via downregulating spinal GFAP/inflammatory burden and improving neurofilament production. Toxicology Mechanisms and Methods 33:7, pages 563-577.
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Articles from other publishers (16)

Yang Jiao, Yue‐Hua Zhang, Chun‐Yan Wang, Yang Yu, Yi‐Ze Li, Wei Cui, Qing Li & Yong‐Hao Yu. (2022) MicroRNA‐7a‐5p ameliorates diabetic peripheral neuropathy by regulating VDAC1/JNK/c‐JUN pathway. Diabetic Medicine 40:1.
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Che Aishah Nazariah Ismail & Idris Long. 2023. Biomarkers in Diabetes. Biomarkers in Diabetes 1089 1110 .
Wen Chen, Xiaotong Wang, Qingyu Sun, Yurui Zhang, Jing Liu, Tingting Hu, Weihua Wu, Chao Wei, Meng Liu, Yumeng Ding, Dianxin Liu, Yingzi Chong, Peipei Wang, Hongwei Zhu, Weihua Cui, Jiannan Zhang, Qian Li & Fei Yang. (2022) The upregulation of NLRP3 inflammasome in dorsal root ganglion by ten-eleven translocation methylcytosine dioxygenase 2 (TET2) contributed to diabetic neuropathic pain in mice. Journal of Neuroinflammation 19:1.
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Xiang Li, Gui-Ying Xiao, Tao Guo, Yu-Jie Song & Qiu-Mei Li. (2022) Potential therapeutic role of pyroptosis mediated by the NLRP3 inflammasome in type 2 diabetes and its complications. Frontiers in Endocrinology 13.
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Yu Jia, Dongze Li, Jing Yu, Wenli Jiang, Xiaoyang Liao & Qian Zhao. (2022) Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review. Frontiers in Cardiovascular Medicine 9.
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Qian-qian Wang, Meng Wang, Yan Li, Yong-hui Liu & Lian-qing Sun. (2022) Attenuation of Oxidative Stress-Induced Cell Apoptosis and Pyroptosis in RSC96 Cells by Salvianolic Acid B. Chinese Journal of Integrative Medicine 28:3, pages 243-248.
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Che Aishah Nazariah Ismail & Idris Long. 2022. Biomarkers in Diabetes. Biomarkers in Diabetes 1 23 .
Suzanne M. Green‐Fulgham, Jayson B. Ball, Steven F. Maier, Kenner C. Rice, Linda R. Watkins & Peter M. Grace. (2020) Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists. Journal of Neuroscience Research 100:1, pages 265-277.
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Qing Sun, Rui Zhang, Xiaowei Xue, Qunli Wu, Dan Yang, Chao Wang, Bin Yan & Xiaochun Liang. (2021) Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats. Frontiers in Pharmacology 12.
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Wei Song, Ying Sun, Xiao-chun Liang, Qian Zhang, Jun Xie, Chao Wang & Wei Liu. (2021) Jinmaitong ameliorates diabetes-induced peripheral neuropathy in rats through Wnt/β-catenin signaling pathway. Journal of Ethnopharmacology 266, pages 113461.
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Ying Bai, Qianqian Mu, Xueli Bao, Jiacheng Zuo, Xin Fang, Jing Hua, Dongwei Zhang, Guangjian Jiang, Ping Li, Sihua Gao & Dandan Zhao. (2021) Targeting NLRP3 Inflammasome in the Treatment Of Diabetes and Diabetic Complications: Role of Natural Compounds from Herbal Medicine. Aging and disease 12:7, pages 1587.
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Jun Xie, Wei Song, Xiaochun Liang, Qian Zhang, Yue Shi, Wei Liu & Xiaohu Shi. (2020) Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin 1. Aging 12:17, pages 17436-17458.
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Stefano Menini, Carla Iacobini, Martina Vitale & Giuseppe Pugliese. (2020) The Inflammasome in Chronic Complications of Diabetes and Related Metabolic Disorders. Cells 9:8, pages 1812.
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Yuan Gao, Shuchun Chen, Minmin Peng, Zi Wang, Luping Ren, Shumin Mu & Meiling Zheng. (2020) Correlation Between Thioredoxin-Interacting Protein and Nerve Conduction Velocity in Patients With Type 2 Diabetes Mellitus. Frontiers in Neurology 11.
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Hao Li, Shulin Liu, Zheng Wang, Yonglai Zhang & Kaiguo Wang. (2020) Hydrogen sulfide attenuates diabetic neuropathic pain through NO/cGMP/PKG pathway and μ-opioid receptor. Experimental Biology and Medicine 245:9, pages 823-834.
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Murat Gürbüz & Serdal Öğüt. (2020) Antidiabetic effect of olive leaf extract on streptozotocin-induced diabetes mellitus in experimental animals. Nutrición Hospitalaria.
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