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Diabetes, Metabolic Syndrome and Obesity Volume 16, 2023 - Issue
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ORIGINAL RESEARCH

Association of Met420del Variant of Metformin Transporter Gene SLC22A1 with Metformin Treatment Response in Ethiopian Patients with Type 2 Diabetes

Abraham Degaga1 Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia;2 Department of Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
,
Sisay Sirgu3 Department of Internal Medicine, Diabetes and Endocrinology Unit, Saint Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia
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Hasniza Zaman Huri2 Department of Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
,
Maw Shin Sim4 Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
,
Tedla Kebede5 Department of Internal Medicine, Diabetes and Endocrinology Unit, Addis Ababa University, Addis Ababa, EthiopiaORCID Iconhttps://orcid.org/0000-0003-2806-9205
ORCID Icon,
Birhanemeskel Tegene6 Department of Microbiology, Saint Paul Hospital Millennium Medical College, Addis Ababa, EthiopiaORCID Iconhttps://orcid.org/0000-0002-0011-2999
ORCID Icon,
Navin Kumar Loganadan7 Department of Pharmacy, Putrajaya Hospital, Precinct 7, Putrajaya, 62250, MalaysiaORCID Iconhttps://orcid.org/0000-0001-6875-8537
ORCID Icon,
Ephrem Engidawork1 Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaORCID Iconhttps://orcid.org/0000-0002-9931-6421
ORCID Icon &
Workineh Shibeshi1 Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3478-6235
ORCID Icon show all
Pages 2523-2535 | Received 19 Jun 2023, Accepted 12 Aug 2023, Published online: 23 Aug 2023

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Abraham Degaga, Sisay Sirgu, Hasniza Zaman Huri, Maw Shin Sim, Navin Kumar Loganadan, Tedla Kebede, Birhanemeskel Tegene, Ephrem Engidawork & Workineh Shibeshi. (2024) Association of the Reduced Function Met420del Polymorphism of SLC22A1 with Metformin-Induced Gastrointestinal Intolerance in Ethiopian Patients with Type 2 Diabetes Mellitus. Pharmacogenomics and Personalized Medicine 17, pages 183-191.
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