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Diabetes, Metabolic Syndrome and Obesity Volume 9, 2016 - Issue

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Original Research

A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

Akihiro Tojo1 Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, JapanCorrespondence[email protected]

Satoshi Kinugasa1 Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan

Toshiro Fujita2 Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan

Christopher S Wilcox3 Division of Nephrology and Hypertension, Center for Hypertension, Kidney and Vascular Research, Georgetown University, Washington, DC, USA

Pages 1-10 | Published online: 18 Jan 2016

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Chuanming Xu, Yanting Chen, Nirupama Ramkumar, Chang‐Jiang Zou, Curt D. Sigmund & Tianxin Yang. (2022) Collecting duct renin regulates potassium homeostasis in mice. Acta Physiologica 237:1.
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Haru Nomura, Sanjaya Kuruppu & Niwanthi W. Rajapakse. (2022) Stimulation of Angiotensin Converting Enzyme 2: A Novel Treatment Strategy for Diabetic Nephropathy. Frontiers in Physiology 12.
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Maria Jose Soler, Conxita Jacobs-Cachá, Manga Motrapu & Hans-Joachim Anders. 2022. Diabetes and Kidney Disease. Diabetes and Kidney Disease 75 104 .

Bruna Visniauskas, Danielle Y. Arita, Carla B. Rosales, Mohammed A. Feroz, Christina Luffman, Michael J. Accavitti, Gabrielle Dawkins, Jennifer Hong, Andrew C. Curnow, Tina K. Thethi, John J. Lefante, Edgar A. Jaimes, Franck Mauvais-Jarvis, Vivian A. Fonseca & Minolfa C. Prieto. (2021) Sex differences in soluble prorenin receptor in patients with type 2 diabetes. Biology of Sex Differences 12:1.
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Yuan SunAlexandre Goes MartiniManoe J. JanssenIngrid M. GarreldsRosalinde MasereeuwXifeng LuA.H. Jan Danser. (2020) Megalin. Hypertension 75:5, pages 1242-1250.
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Yuan Sun, Xifeng Lu & A. H. Jan Danser. (2020) Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?. Current Hypertension Reports 22:4.
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Atsuhiro Ichihara & Midori Sasaki Yatabe. (2019) The (pro)renin receptor in health and disease. Nature Reviews Nephrology 15:11, pages 693-712.
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Jun Ho Lee, Su Jin Jang & Seonkyeong Rhie. (2018) Antinatriuretic phenomena seen in children with acute pyelonephritis may be related to the activation of intrarenal RAAS. Medicine 97:36, pages e12152.
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Santosh Kumar Goru & Anil Bhanudas Gaikwad. (2018) Novel reno-protective mechanism of Aspirin involves H2AK119 monoubiquitination and Set7 in preventing type 1 diabetic nephropathy. Pharmacological Reports 70:3, pages 497-502.
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Akihiro Tojo, Saaya Hatakeyama, Masaomi Nangaku & Toshihiko Ishimitsu. (2018) H+-ATPase blockade reduced renal gluconeogenesis and plasma glucose in a diabetic rat model. Medical Molecular Morphology 51:2, pages 89-95.
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Hicham Labazi, Bunyen Teng & S. Jamal Mustafa. (2018) Functional changes in vascular reactivity to adenosine receptor activation in type I diabetic mice. European Journal of Pharmacology 820, pages 191-197.
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Bryan A. Wilson, Nildris Cruz-Diaz, Yixin Su, James C. Rose, TanYa M. Gwathmey & Mark C. Chappell. (2017) Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake. American Journal of Physiology-Renal Physiology 312:5, pages F879-F886.
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Sandeep Kaur & Arunachalam Muthuraman. (2016) Therapeutic evaluation of rutin in two-kidney one-clip model of renovascular hypertension in rat. Life Sciences 150, pages 89-94.
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A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

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A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

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