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Original Research

Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China

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Pages 217-227 | Published online: 22 Jan 2020

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Zheming Wang, Zhihua Tang, Hamid Heidari, Leila Molaeipour, Roya Ghanavati, Hossein Kazemian, Faramarz Koohsar & Ebrahim Kouhsari. (2023) Global status of phenotypic pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates: an updated systematic review and meta-analysis. Journal of Chemotherapy 35:7, pages 583-595.
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HM Adnan Hameed, Cuiting Fang, Zhiyong Liu, Yanan Ju, Xingli Han, Yamin Gao, Shuai Wang, Gift Chiwala, Yaoju Tan, Ping Guan, Jinxing Hu, Xiaoli Xiong, Jiacong Peng, Yongping Lin, Muzammal Hussain, Nanshan Zhong, Dmitry A Maslov, Gregory M Cook, Jianxiong Liu & Tianyu Zhang. (2022) Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China. Infection and Drug Resistance 15, pages 5655-5666.
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Articles from other publishers (12)

Samuel J. Modlin, Mikael Mansjö, Jim Werngren, Chidera M. Ejike, Sven E. Hoffner & Faramarz Valafar. (2023) Pyrazinamide-resistant Tuberculosis Obscured From Common Targeted Molecular Diagnostics. Drug Resistance Updates 68, pages 100959.
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Amina Al-Jardani, Fatma Al Yaquobi, Chamila Adikaram, Adil Al Wahaibi, Laila Al-Balushi, Samiya Al-Zadjali, Bader Al Abri, Khalsa Al-Thuhli & Seif Al-Abri. (2023) Genomic and geospatial epidemiology of Mycobacterium tuberculosis in Oman: first national insight using whole genome sequencing. International Journal of Infectious Diseases.
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Nicolas de Oliveira Rossini & Marcio Vinicius Bertacine Dias. (2023) Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line. Genetics and Molecular Biology 46:1 suppl 2.
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Ananthi Rajendran & Kannan Palaniyandi. (2022) Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis: A Review and Update. Current Microbiology 79:11.
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Dipti Shrestha, Bhagwan Maharjan, Jeewan Thapa, Mwangala Lonah Akapelwa, Precious Bwalya, Joseph Yamweka Chizimu, Chie Nakajima & Yasuhiko Suzuki. (2022) Detection of Mutations in pncA in Mycobacterium tuberculosis Clinical Isolates from Nepal in Association with Pyrazinamide Resistance. Current Issues in Molecular Biology 44:9, pages 4132-4141.
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Wuan-Geok Saw, Chen Yen Leow, Amaravadhi Harikishore, Joon Shin, Malcolm S. Cole, Wassihun Wedajo Aragaw, Priya Ragunathan, Pooja Hegde, Courtney C. Aldrich, Thomas Dick & Gerhard Grüber. (2022) Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor . ACS Infectious Diseases 8:7, pages 1324-1335.
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Shasank S. Swain, Sanghamitra Pati & Tahziba Hussain. (2022) Quinoline heterocyclic containing plant and marine candidates against drug-resistant Mycobacterium tuberculosis: A systematic drug-ability investigation. European Journal of Medicinal Chemistry 232, pages 114173.
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Wei Yu, Buhari Yusuf, Shuai Wang, Xirong Tian, H. M. Adnan Hameed, Zhili Lu, Gift Chiwala, Md Shah Alam, Gregory M. Cook, Dmitry A. Maslov, Nanshan Zhong & Tianyu Zhang. (2021) Sterilizing Effects of Novel Regimens Containing TB47, Clofazimine, and Linezolid in a Murine Model of Tuberculosis. Antimicrobial Agents and Chemotherapy 65:10.
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Priya Ragunathan, Malcolm Cole, Chitra Latka, Wassihun Wedajo Aragaw, Pooja Hegde, Joon Shin, Malathy Sony Subramanian Manimekalai, Sankaranarayanan Rishikesan, Courtney C. Aldrich, Thomas Dick & Gerhard Grüber. (2021) Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor . ACS Chemical Biology 16:6, pages 1030-1039.
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Samuel J. Modlin, Tyler Marbach, Jim Werngren, Mikael Mansjö, Sven E. Hoffner & Faramarz Valafar. (2021) Atypical Genetic Basis of Pyrazinamide Resistance in Monoresistant Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy 65:6.
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Kun Li, Zhongping Yang, Jing Gu, Ming Luo, Jiaoyu Deng & Yaokai Chen. (2021) Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China. Frontiers in Microbiology 11.
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Wei Yu, Gift Chiwala, Yamin Gao, Zhiyong Liu, Sanjeep Sapkota, Zhili Lu, Lingmin Guo, Shahzad Akbar Khan, Nanshan Zhong & Tianyu Zhang. (2020) TB47 and clofazimine form a highly synergistic sterilizing block in a second-line regimen for tuberculosis in mice. Biomedicine & Pharmacotherapy 131, pages 110782.
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