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Review

How Phages Overcome the Challenges of Drug Resistant Bacteria in Clinical Infections

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Pages 45-61 | Published online: 07 Jan 2020

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Aditi Singh, Sudhakar Padmesh, Manish Dwivedi & Irena Kostova. (2022) How Good are Bacteriophages as an Alternative Therapy to Mitigate Biofilms of Nosocomial Infections. Infection and Drug Resistance 15, pages 503-532.
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Majid Taati Moghadam, Amin Khoshbayan, Zahra Chegini, Iman Farahani & Aref Shariati. (2020) Bacteriophages, a New Therapeutic Solution for Inhibiting Multidrug-Resistant Bacteria Causing Wound Infection: Lesson from Animal Models and Clinical Trials. Drug Design, Development and Therapy 14, pages 1867-1883.
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Mahsa Shahbandeh, Majid Taati Moghadam, Reza Mirnejad, Shiva Mirkalantari & Mehrnaz Mirzaei. (2020) The Efficacy of AgNO3 Nanoparticles Alone and Conjugated with Imipenem for Combating Extensively Drug-Resistant Pseudomonas aeruginosa. International Journal of Nanomedicine 15, pages 6905-6916.
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Guanxiang Liang & Frederic D. Bushman. (2021) The human virome: assembly, composition and host interactions. Nature Reviews Microbiology 19:8, pages 514-527.
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Klaudia T. Angula, Lesetja J. Legoabe & Richard M. Beteck. (2021) Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010–2020 Review. Pharmaceuticals 14:5, pages 461.
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Shamim I. Ahmad. 2021. Human Viruses: Diseases, Treatments and Vaccines. Human Viruses: Diseases, Treatments and Vaccines 663 692 .
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