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Infection and Drug Resistance Volume 14, 2021 - Issue
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Original Research

In vitro and in vivo Effect of Antimicrobial Agent Combinations Against Carbapenem-Resistant Klebsiella pneumoniae with Different Resistance Mechanisms in China

Enbo Liu1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China
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Peiyao Jia1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China;2 Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
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Xue Li1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China;3 Department of Clinical Laboratory, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China
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Menglan Zhou1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China;2 Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-1241-6153
ORCID Icon,
Timothy Kudinha4 School of Biomedical Sciences, Charles Sturt University, Orange, 2800, Australia;5 Pathology West, NSW Health Pathology, Orange, 2800, AustraliaORCID Iconhttps://orcid.org/0000-0003-4035-4789
ORCID Icon,
Chuncai Wu1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China
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Yingchun Xu1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China
&
Qiwen Yang1 Department of Clinical Laboratory, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of ChinaCorrespondence[email protected]
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Pages 917-928 | Published online: 05 Mar 2021

Citations (6)

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Read on this site (2)

Xiuyun Li, Zhaowen Chen, Jin Jiao, Shifu Wang, Yuehua Wang, Weiwei Wu, Huijun Yang & Hongxiang Lou. (2023) In vitro and in vivo activity of meropenem+avibactam against MBL-producing carbapenem-resistant Klebsiella pneumoniae. Expert Review of Anti-infective Therapy 21:1, pages 91-98.
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Guixiang Tao, Hua Tan, Jingjing Ma & Qian Chen. (2022) Resistance Phenotype and Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Isolated from Nanjing Children’s Hospital in Jiangsu Province, China. Infection and Drug Resistance 15, pages 5435-5447.
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Articles from other publishers (4)

Peiyao Jia, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Wei Yu, Rui Li, Xue Li, Mei Kang, Yingchun Xu & Qiwen Yang. (2022) Emergence of a Novel NDM-5-Producing Sequence Type 4523 Klebsiella pneumoniae Strain Causing Bloodstream Infection in China. Microbiology Spectrum 10:5.
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Cansel VatanseverBerna OzerNazlı AtacOrhan Ulas GulerBilge Kaan KilicogluMetehan BerkkanDefne BaskurtEgemen SeverOzlem Dogan & Fusun Can. (2022) Efficacy of Amikacin and Meropenem on Colistin-Induced Klebsiella pneumoniae Persisters . Microbial Drug Resistance 28:7, pages 765-772.
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Marios Karvouniaris, Garyphallia Poulakou, Konstantinos Tsiakos, Maria Chatzimichail, Panagiotis Papamichalis, Anna Katsiaflaka, Katerina Oikonomou, Antonios Katsioulis, Eleni Palli & Apostolos Komnos. (2022) ICU-Associated Gram-Negative Bloodstream Infection: Risk Factors Affecting the Outcome Following the Emergence of Colistin-Resistant Isolates in a Regional Greek Hospital. Antibiotics 11:3, pages 405.
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Pawarisa Terbtothakun, Ozioma Forstinus Nwabor, Thanyaluck Siriyong, Supayang P. Voravuthikunchai & Sarunyou Chusri. (2021) Synergistic Antibacterial Effects of Meropenem in Combination with Aminoglycosides against Carbapenem-Resistant Escherichia coli Harboring blaNDM-1 and blaNDM-5. Antibiotics 10:8, pages 1023.
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