Advanced search
Publication Cover
Infection and Drug Resistance Volume 14, 2021 - Issue
Submit an article Journal homepage
598
Views
14
CrossRef citations to date
0
Altmetric
Original Research

rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis

Ma-chao Li1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
,
Jie Lu2 Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-1097-4450
ORCID Icon,
Yao Lu1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China;3 School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, People’s Republic of China
,
Tong-yang Xiao4 Guangdong Key Laboratory for Diagnosis & Treatment of Emerging Infectious Diseases, Shenzhen Third People’s Hospital, Southern University of Science and Technology, Shenzhen, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-8483-2856
ORCID Icon,
Hai-can Liu1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-9420-1211
ORCID Icon,
Shi-qiang Lin5 Department of Bioinformatics, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, People’s Republic of China
,
Da Xu1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
,
Gui-lian Li1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
,
Xiu-qin Zhao1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
,
Zhi-guang Liu1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
,
Li-li Zhao1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Kang-lin Wan1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
 show all
Pages 4119-4128 | Published online: 05 Oct 2021

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Ma-Chao Li, Xiao-Yue Wang, Tong-Yang Xiao, Shi-Qiang Lin, Hai-Can Liu, Cheng Qian, Da Xu, Gui-Lian Li, Xiu-Qin Zhao, Zhi-Guang Liu, Li-Li Zhao & Kang-Lin Wan. (2022) rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosis. Infection and Drug Resistance 15, pages 6853-6861.
Read now
HM Adnan Hameed, Cuiting Fang, Zhiyong Liu, Yanan Ju, Xingli Han, Yamin Gao, Shuai Wang, Gift Chiwala, Yaoju Tan, Ping Guan, Jinxing Hu, Xiaoli Xiong, Jiacong Peng, Yongping Lin, Muzammal Hussain, Nanshan Zhong, Dmitry A Maslov, Gregory M Cook, Jianxiong Liu & Tianyu Zhang. (2022) Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China. Infection and Drug Resistance 15, pages 5655-5666.
Read now

Articles from other publishers (12)

Ebtisam S.A. Hassanin, Aliae AR. Mohamed Hussein, Shaimaa S. Abdelrheem, Ebtehal Dongol, Ahmed Hamdy Ahmed Mhsb, Asmaa M. Zahran, Mohamed Zein & Islam G. Sayed. (2023) Frequency of rifampicin-resistant mycobacterium tuberculosis by GeneXpert MTB/RIF assay and its correlates among 2605 probable tuberculosis patients in upper Egypt. Indian Journal of Tuberculosis 70:3, pages 345-355.
Crossref
Yesha Patel, Vijay Soni, Kyu Y. Rhee & John D. Helmann. (2023) Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility . mBio 14:2.
Crossref
Hui-Jin Yu, Tae Yeul Kim, Gangmin Kim, Hyang Jin Shim, On Kyun Kang, Seungmo Kim, Chang-Ki Kim, Byung Woo Jhun, Nam Yong Lee, Hee Jae Huh & Hee Joo Lee. (2023) Performance Evaluation of the BACTEC MGIT 960 System for Rifampin Drug-Susceptibility Testing of Mycobacterium tuberculosis Using the Current WHO Critical Concentration. Journal of Clinical Microbiology 61:1.
Crossref
Gaihua Cao, Yue Qiu, Keyi Long, Yi Ma, Huibo Luo, Mei Yang, Jingzhou Hou, Danqun Huo & Changjun Hou. (2022) Rapid and Ultrasensitive Approach for the Simultaneous Detection of Multilocus Mutations to Distinguish Rifampicin-Resistant Mycobacterium tuberculosis . Analytical Chemistry 94:50, pages 17653-17661.
Crossref
Sukanya Saikaew, Aksara Thongprachum, Rodjana Pongsararuk, Aungkana Thanraka, Naowarat Kunyanone, Boonchai Chaiyasirinroje, Praphan Luangsook, Bordin Butr-Indr, Ponrut Phunpae & Usanee Wattananandkul. (2022) Genotypic Distribution and the Epidemiology of Multidrug Resistant Tuberculosis in Upper Northern Thailand. Antibiotics 11:12, pages 1733.
Crossref
Gustavo Adolfo Bermudez-Hernández, Damián Eduardo Pérez-Martínez, Carlos Francisco Madrazo-Moya, Irving Cancino-Muñoz, Iñaki Comas & Roberto Zenteno-Cuevas. (2022) Whole genome sequencing analysis to evaluate the influence of T2DM on polymorphisms associated with drug resistance in M. tuberculosis. BMC Genomics 23:1.
Crossref
Christine Vanlalbiakdiki Sailo, Ralte Lalremruata, Zothan Sanga, Vanlal Fela, Febiola Kharkongor, Zothankhuma Chhakchhuak, Lily Chhakchhuak, Lalnun Nemi, John Zothanzama & Nachimuthu Senthil Kumar. (2022) Distribution and frequency of common mutations in rpoB gene of Mycobacterium tuberculosis detected by Xpert MTB/RIF and identification of residential areas of rifampicin resistant-TB cases: A first retrospective study from Mizoram, Northeast India. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases 29, pages 100342.
Crossref
Amala Bhagwat, Aditi Deshpande & Tanya Parish. (2022) How Mycobacterium tuberculosis drug resistance has shaped anti-tubercular drug discovery. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Ming-Chih Yu, Ching-Sheng Hung, Chun-Kai Huang, Cheng-Hui Wang, Yu-Chih Liang & Jung-Chun Lin. (2022) Differential Impact of the rpoB Mutant on Rifampin and Rifabutin Resistance Signatures of Mycobacterium tuberculosis Is Revealed Using a Whole-Genome Sequencing Assay . Microbiology Spectrum 10:4.
Crossref
Dali Wang, Qing Ning, Ziqing Deng, Meng Zhang & Jing You. (2022) Role of environmental stresses in elevating resistance mutations in bacteria: Phenomena and mechanisms. Environmental Pollution 307, pages 119603.
Crossref
Aynias Seid, Nega Berhane & Semira Nureddin. (2022) Frequency of rpoB, katG, and inhA Gene Polymorphisms Associated with Multidrug-Resistant Mycobacterium tuberculosis Complex Isolates among Ethiopian TB Patients: A Systematic Review. Interdisciplinary Perspectives on Infectious Diseases 2022, pages 1-9.
Crossref
Pejman Bakhtiyariniya, Azar Dokht Khosravi, Mohammad Hashemzadeh & Mohammad Savari. (2022) Identification of mutations in rpoB, pncA, embB, and ubiA genes among drug-resistant Mycobacterium tuberculosis clinical isolates from Iran. Acta Microbiologica et Immunologica Hungarica.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.