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Infection and Drug Resistance Volume 15, 2022 - Issue
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REVIEW

Application of Droplet Digital PCR to Detection of Mycobacterium tuberculosis and Mycobacterium leprae Infections: A Narrative Review

Yuxin Fan1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of China;3 Yunnan Province Key Laboratory of Children’s Major Diseases Research, The Affiliated Children Hospital, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Jingjing Chen1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;4 Department of Biochemistry and Molecular Biology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Meixiao Liu1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Xin Xu1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Yu Zhang1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of China;3 Yunnan Province Key Laboratory of Children’s Major Diseases Research, The Affiliated Children Hospital, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Peng Yue1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;4 Department of Biochemistry and Molecular Biology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Wenjing Cao1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;4 Department of Biochemistry and Molecular Biology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Zhenhua Ji1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Xuan Su1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Shiyuan Wen1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of China;3 Yunnan Province Key Laboratory of Children’s Major Diseases Research, The Affiliated Children Hospital, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Jing Kong1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Guozhong Zhou1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Bingxue Li1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Yan Dong1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaView further author information
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Aihua Liu1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;3 Yunnan Province Key Laboratory of Children’s Major Diseases Research, The Affiliated Children Hospital, Kunming Medical University, Kunming, 650030, People’s Republic of China;4 Department of Biochemistry and Molecular Biology, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-5726-6211View further author information
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Fukai Bao1 The Institute for Tropical Medicine, Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, 650500, People’s Republic of China;2 Department of Microbiology and Immunology, Kunming Medical University, Kunming, 650030, People’s Republic of China;3 Yunnan Province Key Laboratory of Children’s Major Diseases Research, The Affiliated Children Hospital, Kunming Medical University, Kunming, 650030, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-2652-6660View further author information
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Pages 1067-1076 | Published online: 15 Mar 2022

Citations (4)

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Read on this site (1)

Yang Zheng, Hui Xia, Xundi Bao, Bing Zhao, Ping He & Yanlin Zhao. (2022) Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium Tuberculosis by Droplet Digital PCR. Infection and Drug Resistance 15, pages 6245-6254.
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Articles from other publishers (3)

Joshua Hadi, Delphine Rapp, Sharduli Dhawan, Sandeep K. Gupta, Tanushree B. Gupta & Gale Brightwell. (2023) Molecular detection and characterization of foodborne bacteria: Recent progresses and remaining challenges. Comprehensive Reviews in Food Science and Food Safety 22:3, pages 2433-2464.
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María de la Soldedad Lagunes-Castro, Aracely López-Monteon, Daniel Guzmán-Gómez & Angel Ramos-Ligonio. 2023. New Advances in Neglected Tropical Diseases. New Advances in Neglected Tropical Diseases.
Ye Win Aung, Kiatichai Faksri, Arunnee Sangka, Kanchana Tomanakan & Wises Namwat. (2023) Detection of Mycobacterium tuberculosis Complex in Sputum Samples Using Droplet Digital PCR Targeting mpt64. Pathogens 12:2, pages 345.
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