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Infection and Drug Resistance Volume 6, 2013 - Issue

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Original Research

The β-lactamase inhibitor avibactam (NXL104) does not induce ampC β-lactamase in Enterobacter cloacae

Christine MiossecNovexel, Romainville, FranceCorrespondence[email protected]

Monique ClaudonNovexel, Romainville, France

Premavathy LevasseurNovexel, Romainville, France

Michael T BlackNovexel, Romainville, France

Pages 235-240 | Published online: 03 Dec 2013

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Wright W Nichols, Patricia A Bradford, Sushmita D Lahiri & Gregory G Stone. (2022) The primary pharmacology of ceftazidime/avibactam: in vitro translational biology . Journal of Antimicrobial Chemotherapy 77:9, pages 2321-2340.
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Diogo Guerra, Pauline Vidal, Olivier Paccoud, Alexis Maillard, Laurene Cachera, Helga Junot, Rémy Gauzit, Jean R. Zahar, Miguel A. Abreu & Alexandre Bleibtreu. (2022) Dual beta-lactam treatment: Pros and cons. Porto Biomedical Journal 7:5, pages e189.
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Silvia López-Argüello, María Montaner, Antonio Oliver & Bartolome Moya. (2021) Molecular Basis of AmpC β-Lactamase Induction by Avibactam in Pseudomonas aeruginosa: PBP Occupancy, Live Cell Binding Dynamics and Impact on Resistant Clinical Isolates Harboring PDC-X Variants. International Journal of Molecular Sciences 22:6, pages 3051.
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Dafna Yahav, Christian G. Giske, Alise Grāmatniece, Henrietta Abodakpi, Vincent H. Tam & Leonard Leibovici. (2020) New β-Lactam–β-Lactamase Inhibitor Combinations. Clinical Microbiology Reviews 34:1.
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J. Andrew N. Alexander, Mariia Radaeva, Dustin T. King, Henry F. Chambers, Artem Cherkasov, Som S. Chatterjee & Natalie C.J. Strynadka. (2020) Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus. Journal of Biological Chemistry 295:32, pages 10870-10884.
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Bassam El Hafi, Sari S. Rasheed, Antoine G. Abou Fayad, George F. Araj & Ghassan M. Matar. (2019) Evaluating the Efficacies of Carbapenem/β-Lactamase Inhibitors Against Carbapenem-Resistant Gram-Negative Bacteria in vitro and in vivo. Frontiers in Microbiology 10.
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Peera Hemarajata, Thomas Amick, Shangxin Yang, Aric Gregson, Cameron Holzmeyer, Karen Bush & Romney M Humphries. (2018) Selection of hyperproduction of AmpC and SME-1 in a carbapenem-resistant Serratia marcescens isolate during antibiotic therapy. Journal of Antimicrobial Chemotherapy 73:5, pages 1256-1262.
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Felipe Francisco Tuon, Jaime L. Rocha & Marcelo R. Formigoni-Pinto. (2017) Pharmacological aspects and spectrum of action of ceftazidime–avibactam: a systematic review. Infection 46:2, pages 165-181.
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Roman S. Kozlov, Olga U. Stetsiouk & Irina V. Andreeva. (2018) Ceftazidime-avibactam: new rules for the game against multidrug-resistant gram-negative bacteria. Clinical Microbiology and Antimicrobial Chemotherapy 20:1, pages 24-34.
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Zahra Shahandeh, Farahnaz Sadighian & Khadije Beigom Rekabpor. (2016) Phenotypic Detection of ESBL, MBL (IMP-1), and AmpC Enzymes, and Their Coexistence in Enterobacter and Klebsiella Species Isolated From Clinical Specimens. International Journal of Enteric Pathogens In press:In press.
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Jianguo Li, Maria Learoyd, Furong Qiu, LeiLei Zhu & Timi Edeki. (2015) A Randomized, Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of Ceftazidime-Avibactam in Healthy Chinese Subjects. Clinical Drug Investigation 36:2, pages 119-126.
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Antoine Tarral & Henri Merdjan. (2015) Effect of Age and Sex on the Pharmacokinetics and Safety of Avibactam in Healthy Volunteers. Clinical Therapeutics 37:4, pages 877-886.
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Premavathy Levasseur, Anne-Marie Girard, Ludovic Lavallade, Christine Miossec, John Pace & Kenneth Coleman. (2014) Efficacy of a Ceftazidime-Avibactam Combination in a Murine Model of Septicemia Caused by Enterobacteriaceae Species Producing AmpC or Extended-Spectrum β-Lactamases. Antimicrobial Agents and Chemotherapy 58:11, pages 6490-6495.
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The β-lactamase inhibitor avibactam (NXL104) does not induce ampC β-lactamase in Enterobacter cloacae

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The β-lactamase inhibitor avibactam (NXL104) does not induce ampC β-lactamase in Enterobacter cloacae

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