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Review

New developments in the treatment of drug-resistant tuberculosis: clinical utility of bedaquiline and delamanid

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Pages 367-378 | Published online: 30 Oct 2015

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Patricia Bento da Silva, Débora Leite Campos, Camila Maríngolo Ribeiro, Isabel Cristiane da Silva & Fernando Rogério Pavan. (2017) New antimycobacterial agents in the pre-clinical phase or beyond: recent advances in patent literature (2001–2016). Expert Opinion on Therapeutic Patents 27:3, pages 269-282.
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Ginenus Fekadu, Tadesse Tolossa, Ebisa Turi, Firomsa Bekele & Getahun Fetensa. (2022) Pretomanid development and its clinical roles in treating tuberculosis. Journal of Global Antimicrobial Resistance 31, pages 175-184.
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Min Qiao, Shanshan Li, Jinfeng Yuan, Weicong Ren, Yuanyuan Shang, Wei Wang, Rongmei Liu, Fuzhen Zhang, Qing Li, Xiao Wu, Jie Lu, Mengqiu Gao & Yu Pang. (2022) Delamanid suppresses CXCL10 expression via regulation of JAK/STAT1 signaling and correlates with reduced inflammation in tuberculosis patients. Frontiers in Immunology 13.
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Saurav Howlader, Min-Jung Kim, M. Rasheduzzaman Jony, Nguyen Phuoc Long, Yong-Soon Cho, Dong-Hyun Kim & Jae-Gook Shin. (2022) Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro . Antimicrobial Agents and Chemotherapy 66:10.
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Ginenus Fekadu, Kenneth K.W. To & Joyce H.S. You. (2021) WITHDRAWN: Pretomanid for the treatment of Mycobacterium tuberculosis: Evidence on the development and clinical roles. Journal of Infection and Public Health.
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Ivan Bastian, Lisa Shephard & Richard Lumb. (2021) Revised guidelines for Australian laboratories performing mycobacteriology testing. Communicable Diseases Intelligence 44.
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Saeed Khoshnood, Mehdi Goudarzi, Elahe Taki, Atieh Darbandi, Ebrahim Kouhsari, Mohsen Heidary, Moloudsadat Motahar, Melika Moradi & Hadi Bazyar. (2021) Bedaquiline: Current status and future perspectives. Journal of Global Antimicrobial Resistance 25, pages 48-59.
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Matthias Zeller, Susan Bogdanowich-Knipp, Pamela Smith, Dale K. Purcell, Mercy Okezue, Daniel T. Smith, Stephen R. Byrn & Kari L. Clase. (2021) Maleate salts of bedaquiline. Acta Crystallographica Section E Crystallographic Communications 77:4, pages 433-445.
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Katijah Khoza-Shangase & Marina Prodromos. (2021) Impact of drug-resistant tuberculosis treatment on hearing function in South African adults: Bedaquiline versus kanamycin. South African Journal of Communication Disorders 68:1.
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Mercy Okezue, Daniel Smith, Matthias Zeller, Stephen R. Byrn, Pamela Smith, Susan Bogandowich-Knipp, Dale K. Purcell & Kari L. Clase. (2020) Crystal structures of salts of bedaquiline. Acta Crystallographica Section C Structural Chemistry 76:11, pages 1010-1023.
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Razia Gaida, Ilse Truter & Charles A. Peters. (2020) Adverse effects of bedaquiline in patients with extensively drug-resistant tuberculosis. Southern African Journal of Infectious Diseases 35:1.
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Dzintars Gotham, Lindsay McKenna, Mike Frick & Erica Lessem. (2020) Public investments in the clinical development of bedaquiline. PLOS ONE 15:9, pages e0239118.
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Yadong Du, Chao Qiu, Xiaohong Chen, Jing Wang, Wei Jing, Hongqiu Pan, Wei Chen, Yufeng Liu, Chunxiang Li, Xiu’e Xi, Hongyun Yin, Jianfeng Zeng, Xia Zhang, Tao Xu, Qingfeng Wang, Ru Guo, Jun Wang, Yu Pang & Naihui Chu. (2020) Treatment Outcome of a Shorter Regimen Containing Clofazimine for Multidrug-resistant Tuberculosis: A Randomized Control Trial in China. Clinical Infectious Diseases 71:4, pages 1047-1054.
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C. A. Aranaga, S. Fraile, A. Torres, A. Falco, F. Michelangeli & H. Takiff. (2020) Antimycobacterial and PknB Inhibitory Activities of Venezuelan Medicinal Plants. International Journal of Microbiology 2020, pages 1-7.
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M. Soledade C.S. Santos, Ana Marta Matos, Marina Reis & Filomena Martins. (2020) Lipophilicity assessment of some isoniazid derivatives active against Mycobacterium tuberculosis. Colloids and Surfaces A: Physicochemical and Engineering Aspects 599, pages 124820.
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Vijay Vinayak Chavan, Alpa Dalal, Sharath Nagaraja, Pruthu Thekkur, Homa Mansoor, Augusto Meneguim, Roma Paryani, Pramila Singh, Stobdan Kalon, Mrinalini Das, Gabriella Ferlazzo & Petros Isaakidis. (2020) Ambulatory management of pre- and extensively drug resistant tuberculosis patients with imipenem delivered through port-a-cath: A mixed methods study on treatment outcomes and challenges. PLOS ONE 15:6, pages e0234651.
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Cátia Teixeira, Cristina Ventura, José R. B. Gomes, Paula Gomes & Filomena Martins. (2020) Cinnamic Derivatives as Antitubercular Agents: Characterization by Quantitative Structure–Activity Relationship Studies. Molecules 25:3, pages 456.
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Cristiane França da Costa, Marcus Vinicius Nora de Souza, Maria Cristina da Silva Lourenço, Elaine Soares Coimbra, Guilherme da Silva Lourenço Carvalho, James Wardell, Stephane Lima Calixto & Juliana da Trindade Granato. (2019) Synthesis and SAR Study of Simple Aryl Oximes and Nitrofuranyl Derivatives with Potent Activity Against Mycobacterium tuberculosis. Letters in Drug Design & Discovery 17:1, pages 12-20.
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Steven J. Berthel, Christopher B. Cooper & Nader Fotouhi. 2019. Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis. Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis 1 25 .
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Helen Cox, Jennifer Hughes, John Black & Mark P Nicol. (2018) Precision medicine for drug-resistant tuberculosis in high-burden countries: is individualised treatment desirable and feasible?. The Lancet Infectious Diseases 18:9, pages e282-e287.
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Samantha Wellington & Deborah T. Hung. (2018) The Expanding Diversity of Mycobacterium tuberculosis Drug Targets . ACS Infectious Diseases 4:5, pages 696-714.
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Mokhitli Morake, Dina Coertzen, Andile Ngwane, Johannes F. Wentzel, Ho Ning Wong, Frans J. Smit, Lyn-Marie Birkholtz, Ray-Dean Pietersen, Bienyameen Baker, Ian Wiid, David D. N'Da & Richard K. Haynes. (2018) Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis. ChemMedChem 13:1, pages 67-77.
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А. G. NАUMOV & А. V. PАVLUNIN. (2018) PERSPECTIVES OF TARGETED CHEMOTHERAPY WITH DELAMANID IN THE TREATMENT REGIMENS OF THOSE WITH MULTIPLE/EXTENSIVE DRUG RESISTANT TUBERCULOSIS. A SUCCESS, CHANCE OR UNCERTAINTY?. TUBERCULOSIS AND LUNG DISEASES 96:11, pages 74-82.
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Naser Al-Tannak & Oludotun Phillips. (2017) Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound. Scientia Pharmaceutica 85:4, pages 34.
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Moloko C. Cholo, Maborwa T. Mothiba, Bernard Fourie & Ronald Anderson. (2017) Mechanisms of action and therapeutic efficacies of the lipophilic antimycobacterial agents clofazimine and bedaquiline. Journal of Antimicrobial Chemotherapy 72:2, pages 338-353.
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