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International Journal of Nanomedicine Volume 11, 2016 - Issue
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Original Research

Preparation, characterization, and evaluation of antitumor effect of Brucea javanica oil cationic nanoemulsions

Ting-ting Liu1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of China
,
Li-Qiu Mu1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of China
,
Wei Dai1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of China
,
Chuan-bang Wang1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of China
,
Xin-Yi Liu1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of China
&
Da-Xiong Xiang1 Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China;2 Institute of Clinical Pharmacy, Central South University, Changsha, People’s Republic of China;3 Key Laboratory for New Technology of Chinese Medicine Preparations of Hunan Province, Changsha, People’s Republic of ChinaCorrespondence[email protected]
Pages 2515-2529 | Published online: 02 Jun 2016

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Omar Abdifetah & Kesara Na-Bangchang. (2019) Pharmacokinetic studies of nanoparticles as a delivery system for conventional drugs and herb-derived compounds for cancer therapy: a systematic review. International Journal of Nanomedicine 14, pages 5659-5677.
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Yue Zhang, Liying Zhang, Qi Zhang, Xitong Zhang, Tong Zhang & Bing Wang. (2018) Enhanced gastric therapeutic effects of Brucea javanica oil and its gastroretentive drug delivery system compared to commercial products in pharmacokinetics study. Drug Design, Development and Therapy 12, pages 535-544.
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Jing Zhao, Shan Liu, Xueyuan Hu, Yunmei Zhang, Shenglei Yan, Hua Zhao, Mei Zeng, Yao Li, Lan Yang & Jingqing Zhang. (2018) Improved delivery of natural alkaloids into lung cancer through woody oil-based emulsive nanosystems. Drug Delivery 25:1, pages 1426-1437.
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Seung-Hun Kim, Chun-Yen Liu, Po-Wei Fan, Chang-Heng Hsieh, Hsuan-Yuan Lin, Ming-Chung Lee & Kang Fang. (2016) The aqueous extract of Brucea javanica suppresses cell growth and alleviates tumorigenesis of human lung cancer cells by targeting mutated epidermal growth factor receptor. Drug Design, Development and Therapy 10, pages 3599-3609.
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Articles from other publishers (20)

Haohao Guo, Yuan Chen, Jing Wang, Huizhong Ma & Yufeng Liu. (2022) A critical review: anti-cancer effects of Brucea javanica and the mechanisms. Pharmacological Research - Modern Chinese Medicine 4, pages 100133.
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Kexin Li, Kunmin Xiao, Shijie Zhu, Yong Wang & Wei Wang. (2022) Chinese Herbal Medicine for Primary Liver Cancer Therapy: Perspectives and Challenges. Frontiers in Pharmacology 13.
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Ahmed Alaa Kassem, Abeer Salama & Amira Mohamed Mohsen. (2022) Formulation and optimization of cationic nanoemulsions for enhanced ocular delivery of dorzolamide hydrochloride using Box-Behnken design: In vitro and in vivo assessments. Journal of Drug Delivery Science and Technology 68, pages 103047.
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Shadab Md, Nabil A. Alhakamy, Shahid Karim, Gamal A Gabr, Mohammad Kashif Iqubal & Samar S. A. Murshid. (2021) Signaling Pathway Inhibitors, miRNA, and Nanocarrier-Based Pharmacotherapeutics for the Treatment of Lung Cancer: A Review. Pharmaceutics 13:12, pages 2120.
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Mohammad A. Altamimi, Afzal Hussain, Sultan Alshehri, Syed Sarim Imam & Usamah Abdulrahman Alnemer. (2021) Development and Evaluations of Transdermally Delivered Luteolin Loaded Cationic Nanoemulsion: In Vitro and Ex Vivo Evaluations. Pharmaceutics 13:8, pages 1218.
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Longyun Wang, Qianqian Yin, Cun Liu, Ying Tang, Changgang Sun & Jing Zhuang. (2021) Nanoformulations of Ursolic Acid: A Modern Natural Anticancer Molecule. Frontiers in Pharmacology 12.
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Zonghua Shi, Majed Alrobaian, Imran Kazmi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Waleed H. Almalki, Abdullah A. Baothman, Hani Choudhry, Mahfoozur Rahman, Thomas J. Webster & Sarwar Beg. (2020) Cationic self-nanoemulsifying formulations of tamoxifen with improved biopharmaceutical attributes and anticancer activity: Systematic development and evaluation. Journal of Molecular Liquids 320, pages 114534.
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Yanleng Huang, Ni Ni, Lijie Zhao, Jiquan Zhang & Lan Shen. (2020) The preparation, evaluation and phase behavior of linker-based coix seed oil microemulsion. Journal of Molecular Liquids 319, pages 114314.
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Bo Kyeong Yoon, Zheng Yi Lim, Won-Yong Jeon, Nam-Joon Cho, Jeong Hoon Kim & Joshua A. Jackman. (2020) Medicinal Activities and Nanomedicine Delivery Strategies for Brucea javanica Oil and Its Molecular Components. Molecules 25:22, pages 5414.
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Abdur Rehman, Seid Mahdi Jafari, Qunyi Tong, Tahreem Riaz, Elham Assadpour, Rana Muhammad Aadil, Sobia Niazi, Imran Mahmood Khan, Qayyum Shehzad, Ahmad Ali & Sohail Khan. (2020) Drug nanodelivery systems based on natural polysaccharides against different diseases. Advances in Colloid and Interface Science 284, pages 102251.
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Yan-Feng Huang, Qiao-Ping Li, Yao-Xing Dou, Tong-Tong Wang, Chang Qu, Jia-Li Liang, Zhi-Xiu Lin, Xiao-Qi Huang, Zi-Ren Su, Jian-Nan Chen & You-Liang Xie. (2019) Therapeutic effect of Brucea javanica oil emulsion on experimental Crohn’s disease in rats: Involvement of TLR4/ NF-κB signaling pathway. Biomedicine & Pharmacotherapy 114, pages 108766.
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Azren Aida Asmawi, Norazlinaliza Salim, Cheng Loong Ngan, Haslina Ahmad, Emilia Abdulmalek, Mas Jaffri Masarudin & Mohd Basyaruddin Abdul Rahman. (2018) Excipient selection and aerodynamic characterization of nebulized lipid-based nanoemulsion loaded with docetaxel for lung cancer treatment. Drug Delivery and Translational Research 9:2, pages 543-554.
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K. Vohra, H. Dureja, V. Garg & R. Dutt. (2019) Current Trends in Phyto-cancer Therapy Using Nanoparticles. Current Nanomedicine 9:1, pages 30-45.
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Yanleng Huang, Jiayi Zhu, Xiao Lin, Yanlong Hong, Yi Feng & Lan Shen. (2019) Potential of Fatty Oils from Traditional Chinese Medicine in Cancer Therapy: A Review for Phytochemical, Pharmacological and Clinical Studies. The American Journal of Chinese Medicine 47:04, pages 727-750.
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Hira Choudhury, Manisha Pandey, Bapi Gorain, Bappaditya Chatterjee, Thiagarajan Madheswaran, Shadab Md, K.-K. Mak, Murtaza Tambuwala, Manish K. Chourasia & Prashant Kesharwani. 2019. Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer. Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer 217 247 .
Dai Fuhong, Gao Xiang, Li Haiying, Wang Jiangye, Gao Xueming & Chai Wenxiao. (2018) Evaluation of efficacy and safety for Brucea javanica oil emulsion in the control of the malignant pleural effusions via thoracic perfusion. BMC Cancer 18:1.
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Yan-Feng Huang, Jiang-Tao Zhou, Chang Qu, Yao-Xing Dou, Qiong-Hui Huang, Zhi-Xiu Lin, Yan-Fang Xian, Jian-Hui Xie, You-Liang Xie, Xiao-Ping Lai & Zi-Ren Su. (2017) Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice. Journal of Ethnopharmacology 198, pages 389-398.
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