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Original Research

Augmenting regional and targeted delivery in the pulmonary acinus using magnetic particles

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Pages 3385-3395 | Published online: 26 Jul 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

P. Worth Longest, Karl Bass, Rabijit Dutta, Vijaya Rani, Morgan L. Thomas, Ahmad El-Achwah & Michael Hindle. (2019) Use of computational fluid dynamics deposition modeling in respiratory drug delivery. Expert Opinion on Drug Delivery 16:1, pages 7-26.
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Wilson Poh, Nurlilah Ab Rahman, Yan Ostrovski, Josué Sznitman, Kevin Pethe & Say Chye Joachim Loo. (2019) Active pulmonary targeting against tuberculosis (TB) via triple-encapsulation of Q203, bedaquiline and superparamagnetic iron oxides (SPIOs) in nanoparticle aggregates. Drug Delivery 26:1, pages 1039-1048.
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Mohammad K. D. Manshadi, Mahsa Saadat, Mehdi Mohammadi, Reza Kamali, Milad Shamsi, Mozhgan Naseh & Amir Sanati-Nezhad. (2019) Magnetic aerosol drug targeting in lung cancer therapy using permanent magnet. Drug Delivery 26:1, pages 120-128.
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Articles from other publishers (14)

Mohammad Rashedul Islam & Yu Feng. (2023) Achieving Targeted Delivery of Chemotherapeutic Particles to Small Airway Tumors via Pulmonary Route Using Endotracheal Catheters: A CFPD Study. Pharmaceuticals 16:2, pages 158.
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Penghui Li, Weiqi Guo, Jinbo Fan, Chen Su, Xiuguo Zhao & Xinxi Xu. (2023) Aerosol deposition in the pulmonary acinar region: Influence of wall motion and interparticle collisions. Journal of Aerosol Science 167, pages 106077.
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Jun Dong, Yue Yang & Yonggang Zhu. (2022) Recent advances in the understanding of alveolar flow. Biomicrofluidics 16:2.
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Mohamed Talaat, Xiuhua April Si, Hiroko Kitaoka & Jinxiang Xi. (2021) Septal destruction enhances chaotic mixing and increases cellular doses of nanoparticles in emphysematous acinus. Nano Express 2:1, pages 010015.
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Yan Ostrovski, Semion Dorfman, Wilson Poh, Say Chye Joachim Loo & Josué Sznitman. (2021) Focused targeting of inhaled magnetic aerosols in reconstructed in vitro airway models. Journal of Biomechanics 118, pages 110279.
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Jinxiang Xi, Mohamed Talaat, Xiuhua April Si & Hiroko Kitaoka. (2021) Micrometer aerosol deposition in normal and emphysematous subacinar models. Respiratory Physiology & Neurobiology 283, pages 103556.
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Mahsa Saadat, Mohammad K.D. Manshadi, Mehdi Mohammadi, Mohammad Javad Zare, Mohammad Zarei, Reza Kamali & Amir Sanati-Nezhad. (2020) Magnetic particle targeting for diagnosis and therapy of lung cancers. Journal of Controlled Release 328, pages 776-791.
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Jun Dong, Yue Yang & Yonggang Zhu. (2020) New insight into air flow distribution in alveoli based on air- and saline-filled lungs. Microfluidics and Nanofluidics 24:9.
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Lihi Shachar-Berman, Saurabh Bhardwaj, Yan Ostrovski, Prashant Das, Pantelis Koullapis, Stavros Kassinos & Josué Sznitman. (2020) In Silico Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract. Pharmaceutics 12:3, pages 230.
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Lihi Shachar-Berman, Yan Ostrovski, Kenichiro Koshiyama, Shigeo Wada, Stavros C. Kassinos & Josué Sznitman. (2019) Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations. European Journal of Pharmaceutical Sciences 137, pages 105003.
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Long Chen & Xia Zhao. (2019) Characterization of air flow and lung function in the pulmonary acinus by fluid-structure interaction in idiopathic interstitial pneumonias. PLOS ONE 14:3, pages e0214441.
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Yan Ostrovski, Simon Dorfman, Maksim Mezhericher, Stavros Kassinos & Josué Sznitman. (2018) Targeted Drug Delivery to Upper Airways Using a Pulsed Aerosol Bolus and Inhaled Volume Tracking Method. Flow, Turbulence and Combustion 102:1, pages 73-87.
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Philipp Hofemeier, Kenishiro Koshiyama, Shigeo Wada & Josué Sznitman. (2018) One (sub-)acinus for all: Fate of inhaled aerosols in heterogeneous pulmonary acinar structures. European Journal of Pharmaceutical Sciences 113, pages 53-63.
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Rami Fishler, Yan Ostrovski, Chao-Yi Lu & Josué Sznitman. (2017) Streamline crossing: An essential mechanism for aerosol dispersion in the pulmonary acinus. Journal of Biomechanics 50, pages 222-227.
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