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International Journal of Nanomedicine Volume 11, 2016 - Issue
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Original Research

In vivo biodistribution, biocompatibility, and efficacy of sorafenib-loaded lipid-based nanosuspensions evaluated experimentally in cancer

Shaomei Yang1 Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, Shandong Province, People’s Republic of China
,
Bo Zhang1 Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, Shandong Province, People’s Republic of China
,
Xiaowei Gong2 Shandong Provincial Key Laboratory of Neuroprotective Drug, Jinan, Shandong Province, People’s Republic of China
,
Tianqi Wang1 Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, Shandong Province, People’s Republic of China
,
Yongjun Liu1 Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, Shandong Province, People’s Republic of China
&
Na Zhang1 Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, Shandong Province, People’s Republic of ChinaCorrespondence[email protected]
Pages 2329-2343 | Published online: 25 May 2016

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Ziyue Wang, Cuicui Wu, Jinren Liu, Shunxin Hu, Junli Yu, Qiangqiamg Yin, Hongda Tian, Zhipeng Ding, Guiqiang Qi, Li Wang & Liguo Hao. (2023) Aptamer-mediated hollow MnO2 for targeting the delivery of sorafenib. Drug Delivery 30:1, pages 28-39.
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Mohamed Fawzi Kabil, Osama A. Badary, Frank Bier, Shaker A. Mousa & Ibrahim M. El-Sherbiny. (2023) A comprehensive review on lipid nanocarrier systems for cancer treatment: fabrication, future prospects and clinical trials. Journal of Liposome Research 0:0, pages 1-43.
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Zihuang Li, Ling Ye, Jingwen Liu, Daizheng Lian & Xianming Li. (2020) Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma. International Journal of Nanomedicine 15, pages 1469-1480.
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Somayeh Handali, Eskandar Moghimipour, Mohsen Rezaei, Zahra Ramezani & Farid Abedin Dorkoosh. (2020) PHBV/PLGA nanoparticles for enhanced delivery of 5-fluorouracil as promising treatment of colon cancer. Pharmaceutical Development and Technology 25:2, pages 206-218.
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Anne Clavreul, Emilie Roger, Milad Pourbaghi-Masouleh, Laurent Lemaire, Clément Tétaud & Philippe Menei. (2018) Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma. Drug Delivery 25:1, pages 1756-1765.
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Shuqin Ni, Lei Qiu, Guodong Zhang, Haiyan Zhou & Yong Han. (2017) Lymph cancer chemotherapy: delivery of doxorubicin–gemcitabine prodrug and vincristine by nanostructured lipid carriers. International Journal of Nanomedicine 12, pages 1565-1576.
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Leiqiang Han, Tianqi Wang, Jingliang Wu, Xiaolan Yin, Hao Fang & Na Zhang. (2016) A facile route to form self-carried redox-responsive vorinostat nanodrug for effective solid tumor therapy. International Journal of Nanomedicine 11, pages 6003-6022.
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Chuanshan Zhang, Jing Li, Tuerganaili Aji, Liang Li, Xiaojuan Bi, Ning Yang, Zhide Li, Hui Wang, Rui Mao, Guodong Lü, Yingmei Shao, Dominique A. Vuitton, Hao Wen & Renyong Lin. (2019) Identification of Functional MKK3/6 and MEK1/2 Homologs from Echinococcus granulosus and Investigation of Protoscolecidal Activity of Mitogen-Activated Protein Kinase Signaling Pathway Inhibitors In Vitro and In Vivo . Antimicrobial Agents and Chemotherapy 63:1.
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Valentina Giglio, Maurizio Viale, Vittorio Bertone, Irena Maric, Rita Vaccarone & Graziella Vecchio. (2017) Cyclodextrin polymers as nanocarriers for sorafenib. Investigational New Drugs 36:3, pages 370-379.
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Jing Zhang, Tianqi Wang, Shengjun Mu, Livesey D Olerile, Xiaoyue Yu & Na Zhang. (2017) Biomacromolecule/lipid hybrid nanoparticles for controlled delivery of sorafenib in targeting hepatocellular carcinoma therapy. Nanomedicine 12:8, pages 911-925.
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