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International Journal of Nanomedicine Volume 13, 2018 - Issue
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Original Research

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines

Yusra A Alyafee1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia;2 Department of Zoology/College of Science/King Saud University (KSU), Riyadh, Kingdom of Saudi Arabia;
,
Manal Alaamery1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Shahad Bawazeer1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Mansour S Almutairi1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Badr Alghamdi1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Nawaf Alomran1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Atia Sheereen1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
,
Maha Daghestani2 Department of Zoology/College of Science/King Saud University (KSU), Riyadh, Kingdom of Saudi Arabia;
&
Salam Massadeh1 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King AbdulAziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia;3 College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Kingdom of Saudi ArabiaCorrespondence[email protected]
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Pages 199-208 | Published online: 28 Dec 2017

Citations (19)

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Read on this site (4)

Jing Wang, Yan Zhang, GuangPeng Zhang, Li Xiang, HaoWen Pang, Kang Xiong, Yun Lu, JianMei Li, Jie Dai, Sheng Lin & ShaoZhi Fu. (2022) Radiotherapy-induced enrichment of EGF-modified doxorubicin nanoparticles enhances the therapeutic outcome of lung cancer. Drug Delivery 29:1, pages 588-599.
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Gabriela Mojeiko, Julia Sapienza Passos, Alexsandra Conceição Apolinário & Luciana Biagini Lopes. (2021) Topical Transdermal Chemoprevention of Breast Cancer: Where Will Nanomedical Approaches Deliver Us?. Nanomedicine 16:19, pages 1713-1731.
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Bo Hu, Ying Yan, Fei Tong, Long Xu, Jia Zhu, Guangtao Xu & Ruilin Shen. (2018) Lumbrokinase/paclitaxel nanoparticle complex: potential therapeutic applications in bladder cancer. International Journal of Nanomedicine 13, pages 3625-3640.
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Wen Jen Lin & Wei Chi Lee. (2018) Polysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery. International Journal of Nanomedicine 13, pages 3989-4002.
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Articles from other publishers (15)

Mohini Chaurasia, Romi Singh, Srija Sur & S. J. S. Flora. (2023) A review of FDA approved drugs and their formulations for the treatment of breast cancer. Frontiers in Pharmacology 14.
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Mayur Aalhate, Srushti Mahajan, Hoshiyar Singh, Santosh Kumar Guru & Pankaj Kumar Singh. (2023) Nanomedicine in therapeutic warfront against estrogen receptor–positive breast cancer. Drug Delivery and Translational Research 13:6, pages 1621-1653.
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Zoe Hancox, Haleemah Sa’diyah Hussain & Farshid Sefat. 2023. Principles of Biomaterials Encapsulation : Volume Two. Principles of Biomaterials Encapsulation : Volume Two 661 720 .
Guanglin Zhu, Bing Wang, Guo Feng, Zhirong Zhou, Wei Li, Wen Liu, Hongmei Su, Wenjing Wang, Tiejie Wang & Xie-an Yu. (2022) A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer. Frontiers in Pharmacology 13.
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Aishani Wadhawan, Joga Singh, Himani Sharma, Shristi Handa, Gurpal Singh, Ravinder Kumar, Ravi Pratap Barnwal, Indu Pal Kaur & Mary Chatterjee. (2022) Anticancer Biosurfactant-Loaded PLA–PEG Nanoparticles Induce Apoptosis in Human MDA-MB-231 Breast Cancer Cells. ACS Omega 7:6, pages 5231-5241.
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Rohit Mundel, Tanya Thakur & Mary Chatterjee. (2022) Emerging uses of PLA–PEG copolymer in cancer drug delivery. 3 Biotech 12:2.
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Arfa Nasrine, Mohammed Gulzar Ahmed & Soumya Narayana. (2022) Silk fibroin-anastrozole loaded prolonged-release biodegradable nanomedicine: A promising drug delivery system for breast cancer therapy. Materials Today: Proceedings 68, pages 56-65.
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Joanna Skopinska-Wisniewska, Silvia De la Flor & Justyna Kozlowska. (2021) From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances. International Journal of Molecular Sciences 22:14, pages 7402.
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Salam Massadeh, Iman Almohammed, Eman Barhoush, Mustafa Omer, Nouf Aldhawi, Abdulaziz Almalik & Manal Alaamery. (2021) Development of Epirubicin-Loaded Biocompatible Polymer PLA–PEG–PLA Nanoparticles: Synthesis, Characterization, Stability, and In Vitro Anticancerous Assessment. Polymers 13:8, pages 1212.
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Keerti Mishra, Pooja Ratre, Suresh Thareja & Akhlesh K. Jain. (2021) Polymeric Nanoparticles of Aromatase Inhibitors: A Comprehensive Review. Current Pharmaceutical Design 27:6, pages 855-865.
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Salam Massadeh, Mustafa E Omer, Asmaa Alterawi, Rizwan Ali, Fayez H Alanazi, Fares Almutairi, Wejdan Almotairi, Faris F Alobaidi, Khulud Alhelal, Mansour S Almutairi, Abdulaziz Almalik, Aiman A. Obaidat, Manal Alaamery & Alaa Eldeen Yassin. (2020) Optimized Polyethylene Glycolylated Polymer–Lipid Hybrid Nanoparticles as a Potential Breast Cancer Treatment. Pharmaceutics 12:7, pages 666.
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Aishani Wadhawan, Mary Chatterjee & Gurpal Singh. (2019) Present Scenario of Bioconjugates in Cancer Therapy: A Review. International Journal of Molecular Sciences 20:21, pages 5243.
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Raïssa A.R. Teixeira, Luiz Antônio S. Costa & Antonio C. Sant'Ana. (2019) A proposal for the adsorption of anastrozole anticancer drug on gold nanoparticle surfaces. Journal of Raman Spectroscopy 50:10, pages 1462-1467.
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Ajit Singh, Kalpesh Vaishagya, Rahul K. Verma & Rahul Shukla. (2019) Temperature/pH-Triggered PNIPAM-Based Smart Nanogel System Loaded With Anastrozole Delivery for Application in Cancer Chemotherapy. AAPS PharmSciTech 20:5.
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Dhaval Bhavsar, Jyot Gajjar & Krutika Sawant. (2019) Formulation and development of smart pH responsive mesoporous silica nanoparticles for breast cancer targeted delivery of anastrozole: In vitro and in vivo characterizations. Microporous and Mesoporous Materials 279, pages 107-116.
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