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International Journal of Nanomedicine Volume 13, 2018 - Issue

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Original Research

Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers

Nguyen Hoai An Le1 Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, VIC

Hoang Van Phan1 Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, VIC

Jiaqi Yu2 The Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney, Sydney, NSW, Australia

Hak-Kim Chan2 The Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney, Sydney, NSW, Australia

Adrian Neild1 Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, VIC

Tuncay Alan1 Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, VICCorrespondence[email protected]

Pages 1353-1359 | Published online: 08 Mar 2018

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Jie Liu, Qinghui Fu, Qin Li, Yani Yang, Yue Zhang, Kaili Yang, Guohao Sun, Jiayu Luo, Weigen Lu & Jun He. (2024) Research Strategies for Precise Manipulation of Micro/Nanoparticle Drug Delivery Systems Using Microfluidic Technology: A Review. Pharmaceutical Fronts 06:02, pages e69-e100.
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Han Ge, Jiawang Chen, Yuhong Wang & Chizhong Wang. (2024) Influence of coaxiality on internal mixing of coflow generated droplets. Applied Physics Letters 124:7.
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Huan Zhang, Jie Yang, Rongze Sun, Songren Han, Zhaogang Yang & Lesheng Teng. (2023) Microfluidics for nano-drug delivery systems: From fundamentals to industrialization. Acta Pharmaceutica Sinica B 13:8, pages 3277-3299.
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Rashmita Behera, Sanjaykumar R. Patel & Jigisha K. Parikh. (2023) Hydrodynamics and Transport Mechanism of Microfluidic Mixing in Precipitation of Nanodrugs: A Review. Crystal Research and Technology 58:7.
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Rahul Kumar, Amit K. Thakur, Nilanjana Banerjee, Ashutosh Kumar, Gajendra Kumar Gaurav & Raj Kumar Arya. (2022) Liquid antisolvent crystallization of pharmaceutical compounds: current status and future perspectives. Drug Delivery and Translational Research 13:2, pages 400-418.
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Yun Liu, Guangze Yang, Yue Hui, Supun Ranaweera & Chun‐Xia Zhao. (2022) Microfluidic Nanoparticles for Drug Delivery. Small 18:36.
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Michelle L. Beauvais, Bryan A. Sanchez Monserrate, Tianshi Feng, Renkun Chen, Ping Liu, Peter J. Chupas & Karena W. Chapman. (2022) A mixing-flow reactor for time-resolved reaction measurements distributed in space. Journal of Applied Crystallography 55:2, pages 258-264.
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Amir Pourabed, Jason Brenker, Tayyaba Younas, Lizhong He & Tuncay Alan. (2022) A Lotus shaped acoustofluidic mixer: High throughput homogenisation of liquids in 2 ms using hydrodynamically coupled resonators. Ultrasonics Sonochemistry 83, pages 105936.
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Amir Pourabed, Tayyaba Younas, Chang Liu, Bhuvana K. Shanbhag, Lizhong He & Tuncay Alan. (2021) High throughput acoustic microfluidic mixer controls self-assembly of protein nanoparticles with tuneable sizes. Journal of Colloid and Interface Science 585, pages 229-236.
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Chun Kiu Ng, Hao Deng, Hanchen Li, Wenping Yin, Tuncay Alan & Jacek J. Jasieniak. (2021) Synthesis of CsPbBr 3 perovskite nanocrystals with acoustically actuated millisecond mixing . Journal of Materials Chemistry C 9:1, pages 313-321.
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Joshua Seaberg, Sina Kaabipour, Shohreh Hemmati & Joshua D. Ramsey. (2020) A rapid millifluidic synthesis of tunable polymer-protein nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 154, pages 127-135.
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Lu Zhang, Qinghua Chen, Yao Ma & Jiashu Sun. (2019) Microfluidic Methods for Fabrication and Engineering of Nanoparticle Drug Delivery Systems. ACS Applied Bio Materials 3:1, pages 107-120.
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Preena Shrimal, Girirajsinh Jadeja & Sanjaykumar Patel. (2020) A review on novel methodologies for drug nanoparticle preparation: Microfluidic approach. Chemical Engineering Research and Design 153, pages 728-756.
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Dariush Ashtiani, Alex de Marco & Adrian Neild. (2019) Tailoring surface acoustic wave atomisation for cryo-electron microscopy sample preparation. Lab on a Chip 19:8, pages 1378-1385.
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Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers

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Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers

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