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International Journal of Nanomedicine Volume 13, 2018 - Issue
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Original Research

SN38-loaded <100 nm targeted liposomes for improving poor solubility and minimizing burst release and toxicity: in vitro and in vivo study

Yi-Ping Fang1 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University;2 Department of Medical Research, Kaohsiung Medical University HospitalCorrespondence[email protected]
,
Chih-Hung Chuang3 Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University
,
Yi-Jhun Wu1 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University
,
Hsin-Che Lin1 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University
&
Yun-Chi Lu4 Graduate Institute of Medicine, Collage of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
Pages 2789-2802 | Published online: 10 May 2018

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Qing-rui Qi, Huan Tian, Bao-sen Yue, Bing-tao Zhai & Feng Zhao. (2024) Research Progress of SN38 Drug Delivery System in Cancer Treatment. International Journal of Nanomedicine 19, pages 945-964.
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Xin Zhang, Ronglin Yan, Ziran Wei, Dejun Yang, Zunqi Hu, Yu Zhang, Xin Huang, Hejing Huang & Weijun Wang. (2022) Folate Decorated Multifunctional Biodegradable Nanoparticles for Gastric Carcinoma Active Targeting Theranostics. International Journal of Nanomedicine 17, pages 2493-2502.
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Ting Zhou, Wei Zhang, Dongliang Cheng, Xin Tang, Jianfang Feng & Wei Wu. (2020) Preparation, Characterization, and in vivo Evaluation of NK4-Conjugated Hydroxycamptothecin-Loaded Liposomes. International Journal of Nanomedicine 15, pages 2277-2286.
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Jing Xing, Xiquan Zhang, Zhe Wang, Huanqing Zhang, Peng Chen, Gaoxin Zhou, Chunlong Sun, Ning Gu & Min Ji. (2019) Novel lipophilic SN38 prodrug forming stable liposomes for colorectal carcinoma therapy. International Journal of Nanomedicine 14, pages 5201-5213.
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Articles from other publishers (27)

Jie Huang, Xiao Tang, Ziqiong Yang, Jianqiu Chen, Kun Wang, Chengnan Shi, Zihan Liu, Ming Wu & Qian Du. (2024) Enhancing oral delivery and anticancer efficacy of 7-ethyl-10-hydroxycamptothecin through self-assembled micelles of deoxycholic acid grafted N'-nonyl-trimethyl chitosan. Colloids and Surfaces B: Biointerfaces 234, pages 113736.
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Jinping Huang, Shuwen Huang, Shengjun Liu, Lizhen Feng, Wenxiu Huang, Yao Wang, Dongyi Huang, Tingting Huang & Xingzhen Huang. (2023) Preparation of Tetrandrine Nanocrystals by Microfluidic Method and Its In Vitro and In Vivo Evaluation. AAPS PharmSciTech 25:1.
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Changjun Yu, Faqing Huang, Kinsley Wang, Mengmeng Liu, Warren A. Chow, Xiang Ling, Fengzhi Li, Jason L. Causey, Xiuzhen Huang, Galen Cook-Wiens & Xiaojiang Cui. (2023) Single protein encapsulated SN38 for tumor-targeting treatment. Journal of Translational Medicine 21:1.
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Xin Wang, Chao Yang, Mengya Liao, Yongmei Xie & Jinliang Yang. (2023) Synthesis and In Vitro Anti-tumor Evaluation of Novel Glycoconjugated SN38 Derivatives. Chemistry Letters 52:10, pages 788-790.
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Rozafa Koliqi, Arlinda Daka Grapci, Pranvera Breznica Selmani & Vuk Uskoković. (2022) Gene Expression Effects of the Delivery of SN-38 via Poly(D-L-lactide-co-caprolactone) Nanoparticles Comprising Dense and Collapsed Poloxamer Coronae. Journal of Pharmaceutical Innovation 18:2, pages 585-593.
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Luca Hegedüs, Özlem Okumus, Fabian Mairinger, Till Ploenes, Sebastian Reuter, Martin Schuler, Anja Welt, Silvia Vega-Rubin-de-Celis, Dirk Theegarten, Agnes Bankfalvi, Clemens Aigner & Balazs Hegedüs. (2023) TROP2 expression and SN38 antitumor activity in malignant pleural mesothelioma cells provide a rationale for antibody-drug conjugate therapy. Lung Cancer 178, pages 237-246.
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Jincheng Yang, Lirui Jia, Zhonggui He & Yongjun Wang. (2023) Recent advances in SN-38 drug delivery system. International Journal of Pharmaceutics 637, pages 122886.
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Danjun Wu, Wangyang Zhang, Yi Li, Zejing Zhao, Weili Ji, Hong Liu & Gensheng Yang. (2023) Gold nanorods-loaded chitosan-based nanomedicine platform enabling an effective tumor regression in vivo. International Journal of Pharmaceutics 632, pages 122561.
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Yongwei Liu, Xinghui Li, Renqun Pen, Wei Zuo, Ya Chen, Xiuying Sun, Juhua Gou, Qianwen Guo, Maoling Wen, Wuqi Li, Shuangjiang Yu, Hao Liu & Min Huang. (2022) Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes. BioMedical Engineering OnLine 21:1.
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Roohallah Saberi Riseh, Mohadeseh Hassanisaadi, Masoumeh Vatankhah, Fatemeh Soroush & Rajender S. Varma. (2022) Nano/microencapsulation of plant biocontrol agents by chitosan, alginate, and other important biopolymers as a novel strategy for alleviating plant biotic stresses. International Journal of Biological Macromolecules 222, pages 1589-1604.
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Raghavendra C. Mundargi, Neetika Taneja, Jayeshkumar J. Hadia & Ajay J. Khopade. 2022. Targeted Drug Delivery. Targeted Drug Delivery 69 125 .
Takahiro SasakiJun WatanabeXingyao HeHiroaki KatagiAmreena SuriYukitomo IshiKouki AbeManabu NatsumedaWilliam H. Frey, Peng Zhang & Rintaro Hashizume. (2022) Intranasal delivery of nanoliposomal SN-38 for treatment of diffuse midline glioma. Journal of Neurosurgery, pages 1-10.
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Zeinab Jan, Samaneh Mollazadeh, Khalil Abnous, Seyed Mohammad Taghdisi, Abolghasem Danesh, Mohammad Ramezani & Mona Alibolandi. (2022) Targeted Delivery Platforms for the Treatment of Multiple Sclerosis. Molecular Pharmaceutics 19:7, pages 1952-1976.
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Ana Isabel Fraguas-Sánchez, Irene Lozza & Ana Isabel Torres-Suárez. (2022) Actively Targeted Nanomedicines in Breast Cancer: From Pre-Clinal Investigation to Clinic. Cancers 14:5, pages 1198.
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Sofia Teixeira, Maria Alice Carvalho & Elisabete M. S. Castanheira. (2022) Functionalized Liposome and Albumin-Based Systems as Carriers for Poorly Water-Soluble Anticancer Drugs: An Updated Review. Biomedicines 10:2, pages 486.
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Xiuting He, Zhongcheng Cao, Nuannuan Li, Liuxiang Chu, Jiazhen Wang, Chunyan Zhang, Xiaoyan He, Xiaoyan Lu, Kaoxiang Sun & Qingguo Meng. (2021) Preparation and evaluation of SN-38-loaded MMP-2-responsive polymer micelles. Journal of Drug Delivery Science and Technology 66, pages 102596.
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Danjun Wu, Yi Li, Lixi Zhu, Wangyang Zhang, Shumin Xu, Yan Yang, Qinying Yan & Gensheng Yang. (2021) A biocompatible superparamagnetic chitosan-based nanoplatform enabling targeted SN-38 delivery for colorectal cancer therapy. Carbohydrate Polymers 274, pages 118641.
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Cristina Martín-Sabroso, Irene Lozza, Ana Isabel Torres-Suárez & Ana Isabel Fraguas-Sánchez. (2021) Antibody-Antineoplastic Conjugates in Gynecological Malignancies: Current Status and Future Perspectives. Pharmaceutics 13:10, pages 1705.
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Saikat Ghosh, Ankit Javia, Saritha Shetty, Denish Bardoliwala, Kuntal Maiti, Shubhadeep Banerjee, Ajay Khopade, Ambikanandan Misra, Krutika Sawant & Subhas Bhowmick. (2021) Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches. Journal of Controlled Release 337, pages 27-58.
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Tao-Chieh Yang, Shih-Jung Liu, Wei-Lun Lo, Shu-Mei Chen, Ya-Ling Tang & Yuan-Yun Tseng. (2021) Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle. International Journal of Molecular Sciences 22:11, pages 5557.
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Paul Cressey, Maral Amrahli, Po-Wah So, Wladyslaw Gedroyc, Michael Wright & Maya Thanou. (2021) Image-guided thermosensitive liposomes for focused ultrasound enhanced co-delivery of carboplatin and SN-38 against triple negative breast cancer in mice. Biomaterials 271, pages 120758.
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Sena Karaosmanoglu, Mengjiao Zhou, Bingyang Shi, Xiujuan Zhang, Gareth R. Williams & Xianfeng Chen. (2021) Carrier-free nanodrugs for safe and effective cancer treatment. Journal of Controlled Release 329, pages 805-832.
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Shiqi Hu, Chengyuan Dong, Jinqiang Wang, Kexin Liu, Quan Zhou, Jiajia Xiang, Zhuxian Zhou, Fusheng Liu & Youqing Shen. (2020) Assemblies of indocyanine green and chemotherapeutic drug to cure established tumors by synergistic chemo-photo therapy. Journal of Controlled Release 324, pages 250-259.
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Antonella Zacheo, Luca Bizzarro, Laura Blasi, Clara Piccirillo, Antonio Cardone, Giuseppe Gigli, Andrea Ragusa & Alessandra Quarta. (2020) Lipid-Based Nanovesicles for Simultaneous Intracellular Delivery of Hydrophobic, Hydrophilic, and Amphiphilic Species. Frontiers in Bioengineering and Biotechnology 8.
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M.I. Teixeira, C.M. Lopes, M.H. Amaral & P.C. Costa. (2020) Current insights on lipid nanocarrier-assisted drug delivery in the treatment of neurodegenerative diseases. European Journal of Pharmaceutics and Biopharmaceutics 149, pages 192-217.
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Jingxing Si, Xiaobao Zhao, Shan Gao, Dongsheng Huang & Meihua Sui. (2019) Advances in delivery of Irinotecan (CPT-11) active metabolite 7-ethyl-10-hydroxycamptothecin. International Journal of Pharmaceutics 568, pages 118499.
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Adityanarayan Mohapatra, Saji Uthaman & In-Kyu Park. 2019. Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics. Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics 205 231 .

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