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International Journal of Nanomedicine Volume 13, 2018 - Issue
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Original Research

pH and redox dual-responsive copolymer micelles with surface charge reversal for co-delivery of all-trans-retinoic acid and paclitaxel for cancer combination chemotherapy

Yanqiu Zhang1 Department of Oncology and Hematology, Shuyang Hospital Affiliated to Xuzhou Medical University, Suqian 223600, China;2 Department of Oncology and Hematology, Shuyang People’s Hospital, Suqian 223600, China
,
Lianjun Peng3 Department of Respiratory, Central Hospital of Kaiping City, Kaiping 529300, China
,
Jiahui Chu4 Department of Respiratory and Critical Care Medicine, Fuzong Clinical College of Fujian Medical University, Fuzhou General Hospital, Fuzhou, Fujian 350000, China
,
Ming Zhang5 Department of Thoracic and Cardiac Surgery, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China, [email protected], [email protected], [email protected]
,
Lizhu Sun1 Department of Oncology and Hematology, Shuyang Hospital Affiliated to Xuzhou Medical University, Suqian 223600, China;2 Department of Oncology and Hematology, Shuyang People’s Hospital, Suqian 223600, China
,
Bin Zhong5 Department of Thoracic and Cardiac Surgery, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China, [email protected], [email protected], [email protected]Correspondence[email protected] [email protected] [email protected]
&
Qiyong Wu5 Department of Thoracic and Cardiac Surgery, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China, [email protected], [email protected], [email protected]Correspondence[email protected] [email protected] [email protected]
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Pages 6499-6515 | Published online: 16 Oct 2018

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Yanxu Li, Hao Zou, Zekun Zheng, Zhuoheng Liu, Huiyuan Hu, Wei Wu & Tao Wang. (2023) Advances in the Study of Bioactive Nanoparticles for the Treatment of HCC and Its Postoperative Residual Cancer. International Journal of Nanomedicine 18, pages 2721-2735.
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Chetan Janrao, Shivani Khopade, Akshay Bavaskar, Shyam Sudhakar Gomte, Tejas Girish Agnihotri & Aakanchha Jain. (2023) Recent advances of polymer based nanosystems in cancer management. Journal of Biomaterials Science, Polymer Edition 34:9, pages 1274-1335.
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Gabriel Silva Marques Borges, Flávia Alves Lima, Guilherme Carneiro, Gisele Assis Castro Goulart & Lucas Antônio Miranda Ferreira. (2021) All-trans retinoic acid in anticancer therapy: how nanotechnology can enhance its efficacy and resolve its drawbacks. Expert Opinion on Drug Delivery 18:10, pages 1335-1354.
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Mahua Dhara (Ganguly). (2021) Smart polymeric nanostructures for targeted delivery of therapeutics. Journal of Macromolecular Science, Part A 58:4, pages 269-284.
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Shiya Zhou, Shuwen Fu, Hanle Wang, Yanhao Deng, Xing Zhou, Wei Sun & Yinglei Zhai. (2020) Acetal-linked polymeric prodrug micelles based on aliphatic polycarbonates for paclitaxel delivery: preparation, characterization, in vitro release and anti-proliferation effects. Journal of Biomaterials Science, Polymer Edition 31:15, pages 2007-2023.
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Wanfu Men, Peiyao Zhu, Siyuan Dong, Wenke Liu, Kun Zhou, Yu Bai, Xiangli Liu, Shulei Gong, Can Yang Zhang & Shuguang Zhang. (2019) Fabrication Of Dual pH/redox-Responsive Lipid-Polymer Hybrid Nanoparticles For Anticancer Drug Delivery And Controlled Release. International Journal of Nanomedicine 14, pages 8001-8011.
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Guanglan Ma, Xiao Du, Jianping Zhu, Feng Xu, Hua Yu & Juan Li. (2021) Multi-functionalized dendrimers for targeted co-delivery of sorafenib and paclitaxel in liver cancers. Journal of Drug Delivery Science and Technology 63, pages 102493.
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Yue Yang, Kaiqing Yun, Yunjian Li, Ling Zhang, Wenxuan Zhao, Zhihong Zhu, Baocheng Tian, Fen Chen & Weisan Pan. (2021) Self-assembled multifunctional polymeric micelles for tumor-specific bioimaging and synergistic chemo-phototherapy of cancer. International Journal of Pharmaceutics 602, pages 120651.
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Luzhou Xu, Lei Zhu, Kai Zheng, Junlou Liu, Panpan Tian, Di Hu, Qianqian Wang, Qiaoyun Zuo, Xiaosong Ouyang, Yanna Dai, Yuxian Fu, Xinyi Dai, Fang Huang & Jun Cheng. (2021) The design and synthesis of redox-responsive oridonin polymeric prodrug micelle formulation for effective gastric cancer therapy. Journal of Materials Chemistry B 9:13, pages 3068-3078.
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Miguel Pereira-Silva, Ivana Jarak, Ana Cláudia Santos, Francisco Veiga & Ana Figueiras. (2020) Micelleplex-based nucleic acid therapeutics: From targeted stimuli-responsiveness to nanotoxicity and regulation. European Journal of Pharmaceutical Sciences 153, pages 105461.
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Maria Valeria Giuli, Patrizia Nadia Hanieh, Eugenia Giuliani, Federica Rinaldi, Carlotta Marianecci, Isabella Screpanti, Saula Checquolo & Maria Carafa. (2020) Current Trends in ATRA Delivery for Cancer Therapy. Pharmaceutics 12:8, pages 707.
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Ying Jie Ooi, Yuting Wen, Jingling Zhu, Xia Song & Jun Li. (2020) Surface Charge Switchable Polymer/DNA Nanoparticles Responsive to Tumor Extracellular pH for Tumor-Triggered Enhanced Gene Delivery. Biomacromolecules 21:3, pages 1136-1148.
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Zengjun Fang, Shaobin Pan, Peng Gao, Huagang Sheng, Lingjun Li, Lei Shi, Yongqing Zhang & Xiaoqing Cai. (2020) Stimuli-responsive charge-reversal nano drug delivery system: The promising targeted carriers for tumor therapy. International Journal of Pharmaceutics 575, pages 118841.
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Nayra M. Kamel, Maged W. Helmy, Elsayeda-Zeinab Abdelfattah, Sherine N. Khattab, Doaa Ragab, Magda W. Samaha, Jia-You Fang & Ahmed O. Elzoghby. (2019) Inhalable Dual-Targeted Hybrid Lipid Nanocore–Protein Shell Composites for Combined Delivery of Genistein and All-Trans Retinoic Acid to Lung Cancer Cells. ACS Biomaterials Science & Engineering 6:1, pages 71-87.
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