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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

Acid-responsive nanoparticles as a novel oxidative stress-inducing anticancer therapeutic agent for colon cancer

Chengwei Zhao1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]
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Weilan Cao2 Department of Coloproctology, The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China
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Hailun Zheng1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected];3 Department of Pharmacy, The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China
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Zhongxiang Xiao1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]
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Jie Hu1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected];4 State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau 999078, China
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Lehe Yang1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]
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Min Chen1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]
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Guang Liang1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]
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Suqing Zheng1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]Correspondence[email protected] [email protected]
&
Chengguang Zhao1 Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China, [email protected], [email protected]Correspondence[email protected] [email protected]
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Pages 1597-1618 | Published online: 28 Feb 2019

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Jie Yang, Kailing Li, Dan He, Jing Gu, Jingyu Xu, Jiaxi Xie, Min Zhang, Yuying Liu, Qunyou Tan & Jingqing Zhang. (2020) Toward a better understanding of metabolic and pharmacokinetic characteristics of low-solubility, low-permeability natural medicines. Drug Metabolism Reviews 52:1, pages 19-43.
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Yuping Zhao, Yanna Zhao, Qisan Ma, Bin Sun, Qingpeng Wang, Zhuang Ding, Huaizhen Zhang, Xiuling Chu, Min Liu, Zhengping Wang & Jun Han. (2019) Carrier-Free, Dual-Functional Nanorods Via Self-Assembly Of Pure Drug Molecules For Synergistic Chemo-Photodynamic Therapy. International Journal of Nanomedicine 14, pages 8665-8683.
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Articles from other publishers (15)

Guangyan Zhang, Tianlong Li, Jia Liu, Xinran Wu & Hui Yi. (2023) Cinnamaldehyde-Contained Polymers and Their Biomedical Applications. Polymers 15:6, pages 1517.
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Li Lu, Yuan Xiong, Juan Zhou, Guangji Wang, Bobin Mi & Guohui Liu. (2022) The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity 2022, pages 1-23.
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Yukun Chen, Zhenzhi Wang, Xiaofan Wang, Mingliang Su, Fan Xu, Lian Yang, Lijun Jia & Zhanxia Zhang. (2022) Advances in Antitumor Nano-Drug Delivery Systems of 10-Hydroxycamptothecin. International Journal of Nanomedicine Volume 17, pages 4227-4259.
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Yunhan Wang, Zongying Zhang, Weichen Sun, Jie Zhang, Qiuyun Xu, Xiaorong Zhou & Liming Mao. (2022) Ferroptosis in colorectal cancer: Potential mechanisms and effective therapeutic targets. Biomedicine & Pharmacotherapy 153, pages 113524.
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Qiuxing Liu, Xin Ding, Xiaoyu Xu, Hualu Lai, Zishan Zeng, Ting Shan, Tao Zhang, Meixu Chen, Yanjuan Huang, Zeqian Huang, Xiuling Dai, Meng Xia & Shengmiao Cui. (2022) Tumor-targeted hyaluronic acid-based oxidative stress nanoamplifier with ROS generation and GSH depletion for antitumor therapy. International Journal of Biological Macromolecules 207, pages 771-783.
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Shunli Chu, Xiaolu Shi, Ye Tian & Fengxiang Gao. (2022) pH-Responsive Polymer Nanomaterials for Tumor Therapy. Frontiers in Oncology 12.
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Ruoyan Cao, Weilin Zhang, Hongjian Zhang, Lixuan Wang, Xijuan Chen, Xianyue Ren, Bin Cheng & Juan Xia. (2022) Comprehensive Analysis of the PRDXs Family in Head and Neck Squamous Cell Carcinoma. Frontiers in Oncology 12.
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Anindita Behera & Santwana Padhi. 2022. Polymeric nanoparticles for the treatment of solid tumors. Polymeric nanoparticles for the treatment of solid tumors 401 425 .
Yang Yang, Fuwei Yang, Xiaotian Shan, Jiamin Xu, Wenjie Fang, Juan Zhou, Lipeng Qiu & Jinghua Chen. (2021) Fabrication of pH/Reduction Sensitive Polyethylene Glycol-Based Micelles for Enhanced Intracellular Drug Release. Pharmaceutics 13:9, pages 1464.
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Li Huang, Shaojing Zhao, Fang Fang, Ting Xu, Minhuan Lan & Jinfeng Zhang. (2021) Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy. Biomaterials 268, pages 120557.
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Xuejun Jiang, Mei Lin, Jianwen Huang, Mulan Mo, Houhe Liu, Yuan Jiang, Xiaowen Cai, Wingnang Leung & Chuanshan Xu. (2020) Smart Responsive Nanoformulation for Targeted Delivery of Active Compounds From Traditional Chinese Medicine. Frontiers in Chemistry 8.
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Ramesh Gannimani, Pavan Walvekar, Veluru Ramesh Naidu, Tejraj M. Aminabhavi & Thirumala Govender. (2020) Acetal containing polymers as pH-responsive nano-drug delivery systems. Journal of Controlled Release 328, pages 736-761.
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Laura Cabeza, Gloria Perazzoli, Cristina Mesas, Cristina Jiménez-Luna, José Prados, Ana Rosa Rama & Consolación Melguizo. (2020) Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents. AAPS PharmSciTech 21:5.
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María Julia Martín, Claudia Gentili & Verónica Lassalle. (2020) In vitro Biological Tests as the First Tools To Validate Magnetic Nanotheranostics for Colorectal Cancer Models . ChemMedChem 15:12, pages 1003-1017.
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Riccardo Rampado, Sara Crotti, Paolo Caliceti, Salvatore Pucciarelli & Marco Agostini. (2019) Nanovectors Design for Theranostic Applications in Colorectal Cancer. Journal of Oncology 2019, pages 1-27.
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