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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

Delivering amoxicillin at the infection site – a rational design through lipid nanoparticles

Daniela Lopes-de-Campos1 LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, [email protected]
,
Rita M Pinto1 LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, [email protected]
,
Sofia A Costa Lima1 LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, [email protected]
,
Tiago Santos2 INEB – Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal;3 i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
,
Bruno Sarmento2 INEB – Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal;3 i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;4 IINFACTS, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Instituto Universitário de Ciências da Saúde, Gandra, Portugal
,
Cláudia Nunes1 LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, [email protected]
&
Salette Reis1 LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, [email protected]Correspondence[email protected]
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Pages 2781-2795 | Published online: 23 Apr 2019

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Enes Güncüm, Nuran Işıklan, Ceren Anlaş, Elif Bulut & Tülay Bakırel. (2023) Preparation, characterization, and evaluation of antibacterial and cytotoxic activity of chitosan-polyethylene glycol nanoparticles loaded with amoxicillin as a novel drug delivery system. Journal of Biomaterials Science, Polymer Edition 34:12, pages 1660-1682.
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Sohaib Khan, Mohamed Sharaf, Ishfaq Ahmed, Tehsin Ullah Khan, Samah Shabana, Muhammad Arif, Syed Shabi Ul Hassan Kazmi & Chenguang Liu. (2022) Potential utility of nano-based treatment approaches to address the risk of Helicobacter pylori. Expert Review of Anti-infective Therapy 20:3, pages 407-424.
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Ze-Liang Wu, Jun Zhao & Rong Xu. (2020) Recent Advances in Oral Nano-Antibiotics for Bacterial Infection Therapy. International Journal of Nanomedicine 15, pages 9587-9610.
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Articles from other publishers (19)

Qingshuang Wang, Yurui Cui, Wei Ai, Siqi Li, Zhe Zhang & Xiangru Feng. (2023) Mesoporous silica SBA-15 composite for the delivery of amoxicillin against S. aureus skin infection . New Journal of Chemistry 47:16, pages 7648-7654.
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Mahmoud Kandeel, Mohamed A. Morsy, Hany M. Abd El-Lateef, Mohamed Marzok, Hossam S. El-Beltagi, Khalid M. Al Khodair, Ibrahim Albokhadaim & Katharigatta N. Venugopala. (2023) Cognitive- and memory-enhancing effects of Augmentin in Alzheimer’s rats through regulation of gene expression and neuronal cell apoptosis. Frontiers in Pharmacology 14.
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Manoj Gitte, Shyam Sudhakar Gomte, Tejas Girish Agnihotri, Nidhi Singh & Aakanchha Jain. (2023) Development of amoxicillin Trihydrate-Loaded lyotropic liquid crystal nanoparticles for skin infection. Journal of Molecular Liquids 374, pages 121281.
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Catarina Leal Seabra, Rita M. Pinto, Cláudia Nunes & Salette Reis. 2023. Bioactive Lipids. Bioactive Lipids 209 230 .
Rita M. Pinto, Catarina Leal Seabra, Martine De Jonge, M. Cristina L. Martins, Patrick Van Dijck, Salette Reis & Cláudia Nunes. (2022) Antibiofilm Combinatory Strategy: Moxifloxacin-Loaded Nanosystems and Encapsulated N-Acetyl-L-Cysteine. Pharmaceutics 14:11, pages 2294.
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Cheng-Jung Yao, Shu-Jyuan Yang, Chung-Huan Huang, Yuan-Ting Chang, Chung-Hao Wang, Ming-Jium Shieh & Tai-Horng Young. (2022) Retention Time Extended by Nanoparticles Improves the Eradication of Highly Antibiotic-Resistant Helicobacter pylori. Pharmaceutics 14:10, pages 2117.
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Yanping Wu, Jiayue Geng, Xiaohong Cheng, Ying Yang, Yu Yu, Lili Wang, Quanjiang Dong, Zhe Chi & Chenguang Liu. (2022) Cosmetic-Derived Mannosylerythritol Lipid-B-Phospholipid Nanoliposome: An Acid-Stabilized Carrier for Efficient Gastromucosal Delivery of Amoxicillin for In Vivo Treatment of Helicobacter pylori . ACS Omega 7:33, pages 29086-29099.
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Daniela Lopes-de-Campos, Catarina Leal Seabra, Rita M. Pinto, Mateusz Adam Słowiński, Bruno Sarmento, Cláudia Nunes, M. Cristina L. Martins & Salette Reis. (2022) Targeting and killing the Ever-Challenging ulcer bug. International Journal of Pharmaceutics 617, pages 121582.
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Merve Karpuz & Mine Silindir‐Gunay. 2022. Nanoengineering of Biomaterials. Nanoengineering of Biomaterials 469 503 .
Lide Arana, Lucia Gallego & Itziar Alkorta. (2021) Incorporation of Antibiotics into Solid Lipid Nanoparticles: A Promising Approach to Reduce Antibiotic Resistance Emergence. Nanomaterials 11:5, pages 1251.
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Nupur Ojha & Nilanjana Das. (2021) Green Formulation of Microbial Biopolyesteric Nanocarriers Toward In Vitro Drug Delivery and Its Characterization. Current Microbiology 78:5, pages 2061-2070.
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Mariana Monteiro, Andreia F. R. Silva, Daniela Resende, Susana S. Braga, Manuel A. Coimbra, Artur M. S. Silva & Susana M. Cardoso. (2021) Strategies to Broaden the Applications of Olive Biophenols Oleuropein and Hydroxytyrosol in Food Products. Antioxidants 10:3, pages 444.
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Tânia Moniz, Sofia A. Costa Lima & Salette Reis. (2020) Application of the human stratum corneum lipid-based mimetic model in assessment of drug-loaded nanoparticles for skin administration. International Journal of Pharmaceutics 591, pages 119960.
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Patrycja Golińska & Magdalena Wypij. 2020. Nanobiotechnology in Diagnosis, Drug Delivery, and Treatment. Nanobiotechnology in Diagnosis, Drug Delivery, and Treatment 47 62 .
Heung Up Kim. (2020) Helicobacter pylori Eradication Therapy - Recent Trend in Research. The Korean Journal of Helicobacter and Upper Gastrointestinal Research 20:3, pages 210-217.
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Kristyna Smerkova, Kristyna Dolezelikova, Lucie Bozdechova, Zbynek Heger, Ludek Zurek & Vojtech Adam. (2020) Nanomaterials with active targeting as advanced antimicrobials. WIREs Nanomedicine and Nanobiotechnology 12:5.
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Maie S. Taha, Smrithi Padmakumar, Amit Singh & Mansoor M. Amiji. (2020) Critical quality attributes in the development of therapeutic nanomedicines toward clinical translation. Drug Delivery and Translational Research 10:3, pages 766-790.
Crossref
Lincy Tom, Christy Rosaline Nirmal, Azger Dusthackeer, B. Magizhaveni & M. R. P. Kurup. (2020) Formulation and evaluation of β-cyclodextrin-mediated inclusion complexes of isoniazid scaffolds: molecular docking and in vitro assessment of antitubercular properties . New Journal of Chemistry 44:11, pages 4467-4477.
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Erick A. Argueta & Steven F. Moss. (2019) Treatment of Helicobacter pylori. Current Opinion in Gastroenterology 35:6, pages 544-550.
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