Advanced search
Publication Cover
International Journal of Nanomedicine Volume 14, 2019 - Issue
Submit an article Journal homepage
719
Views
131
CrossRef citations to date
0
Altmetric
Review

Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach

Ghanbar Mahmoodi Chalbatani1 Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran
,
Hassan Dana1 Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran;2 Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
,
Elahe Gharagouzloo1 Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran
,
Santiago Grijalvo3 Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona08034, Spain;4 Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER BBN), Madrid, Spain
,
Ramon Eritja3 Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona08034, Spain;4 Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER BBN), Madrid, Spain
,
Craig D Logsdon5 Department of Cancer Biology, University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA;6 Department of GI Medical Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA
,
Fereidoon Memari1 Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, IranCorrespondence[email protected] [email protected]
,
Seyed Rouhollah Miri1 Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran
,
Mahdi Rezvani Rad7 Department of Biology, Zabol University, Zabol, Iran
&
Vahid Marmari2 Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
 show all
Pages 3111-3128 | Published online: 02 May 2019

Citations (131)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Ahmed Khaled Abosalha, Waqar Ahmad, Jacqueline Boyajian, Paromita Islam, Merry Ghebretatios, Sabrina Schaly, Rahul Thareja, Karan Arora & Satya Prakash. (2023) A comprehensive update of siRNA delivery design strategies for targeted and effective gene silencing in gene therapy and other applications. Expert Opinion on Drug Discovery 18:2, pages 149-161.
Read now
Arif Khan, Ahmed N. Aljarbou, Shamshir Khan & Masood A. Khan. (2022) Her-2-directed systemic delivery of fatty acid synthase (FASN) siRNA with novel liposomal carrier systems in the breast cancer mouse model. Journal of Drug Targeting 30:6, pages 634-645.
Read now
Hazem Choukaife, Salma Seyam, Batoul Alallam, Abd Almonem Doolaanea & Mulham Alfatama. (2022) Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment. International Journal of Nanomedicine 17, pages 3933-3966.
Read now
Gu Gong, Xiuhui Tang, Jiayuan Zhang, Xiao Liang, Jiebing Yang & Quanshun Li. (2021) Phenylboronic Acid-Modified Polyamidoamine Mediated the Transfection of Polo-Like Kinase-1 siRNA to Achieve an Anti-Tumor Efficacy. International Journal of Nanomedicine 16, pages 8037-8048.
Read now
Said M. Afify, Aung Ko Ko Oo, Ghmkin Hassan, Akimasa Seno & Masaharu Seno. (2021) How can we turn the PI3K/AKT/mTOR pathway down? Insights into inhibition and treatment of cancer. Expert Review of Anticancer Therapy 21:6, pages 605-619.
Read now
Changbing Wang, Yu Xia, Shaochuan Huo, Diwen Shou, Qing Mei, Wenjuan Tang, Yinghua Li, Hongsheng Liu, Yongjian Zhou & Bing Zhu. (2020) Silencing of MEF2D by siRNA Loaded Selenium Nanoparticles for Ovarian Cancer Therapy. International Journal of Nanomedicine 15, pages 9759-9770.
Read now
Arif Khan, Ahmed N Aljarbou, Yousef H Aldebasi, Khaled S Allemailem, Mohammed A Alsahli, Shamshir Khan, Abdulmohsen M Alruwetei & Masood A Khan. (2020) Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab’-Immunoliposomes for Gene Silencing in Breast Cancer Cells. International Journal of Nanomedicine 15, pages 5575-5589.
Read now
Marco Napoli & Elsa R. Flores. (2020) The p53 family reaches the final frontier: the variegated regulation of the dark matter of the genome by the p53 family in cancer. RNA Biology 17:11, pages 1636-1647.
Read now

Articles from other publishers (123)

Gamaleldin I. Harisa, Abdelrahman Y. Sherif & Fars K. Alanazi. (2023) Hybrid Lymphatic Drug Delivery Vehicles as a New Avenue for Targeted Therapy: Lymphatic Trafficking, Applications, Challenges, and Future Horizons. The Journal of Membrane Biology 256:3, pages 199-222.
Crossref
Haizhu Kuang, Jing Ma, Xinyu Chi, Qichen Fu, Qianzhe Zhu, Weiling Cao, Peng Zhang & Xin Xie. (2023) Integrated Osteoinductive Factors─Exosome@MicroRNA-26a Hydrogel Enhances Bone Regeneration. ACS Applied Materials & Interfaces 15:19, pages 22805-22816.
Crossref
Elham Allahyari, Kobra Velaei, Zohreh Sanaat, Nazila Jalilzadeh, Amir Mehdizadeh & Mohammad Rahmati. (2022) RNA interference: Promising approach for breast cancer diagnosis and treatment. Cell Biology International 47:5, pages 833-847.
Crossref
Shuyu Piao, Ikjun Lee, Seonhee Kim, Hyewon Park, Harsha Nagar, Su-Jeong Choi, Giang-Huong Vu, Minsoo Kim, Eun-Ok Lee, Byeong-Hwa Jeon, Dong Woon Kim, Youngduk Seo & Cuk-Seong Kim. (2023) CRIF1 siRNA-Encapsulated PLGA Nanoparticles Suppress Tumor Growth in MCF-7 Human Breast Cancer Cells. International Journal of Molecular Sciences 24:8, pages 7453.
Crossref
Lulu Qiao, Jonatan Niño‐Sánchez, Rachael Hamby, Luca Capriotti, Angela Chen, Bruno Mezzetti & Hailing Jin. (2023) Artificial nanovesicles for dsRNA delivery in spray‐induced gene silencing for crop protection . Plant Biotechnology Journal 21:4, pages 854-865.
Crossref
Sayed Sartaj Sohrab, Sherif Aly El-Kafrawy, Zeenat Mirza, Ahmed M. Hassan, Fatima Alsaqaf & Esam Ibraheem Azhar. (2023) Delivery of siRNAs against MERS-CoV in Vero and HEK-293 cells: A comparative evaluation of transfection reagents. Journal of King Saud University - Science 35:3, pages 102540.
Crossref
Xinghua Huang, Jianwei Li, Guanyi Li, Binyu Ni, Ziji Liang, Haodong Chen, Chaozhang Xu, Jianhua Zhou, Jinsheng Huang & Shaohui Deng. (2023) Cation-free siRNA-cored nanocapsules for tumor-targeted RNAi therapy. Acta Biomaterialia 161, pages 226-237.
Crossref
Chenyu Su, Shanshan Liu, Meixue Sun, Qianlong Yu, Changyou Li, Robert I. GrahamXiufang Wang, Xinwei Wang, Pengjun Xu & Guangwei Ren. (2023) Delivery of Methoprene-Tolerant dsRNA to Improve RNAi Efficiency by Modified Liposomes for Pest Control. ACS Applied Materials & Interfaces 15:10, pages 13576-13588.
Crossref
Almog Nadir, Anna Shteinfer-Kuzmine, Swaroop Kumar Pandey, Juan Ortas, Daniel Kerekes & Varda Shoshan-Barmatz. (2023) Pro-Apoptotic and Anti-Cancer Activity of the Vernonanthura Nudiflora Hydroethanolic Extract. Cancers 15:5, pages 1627.
Crossref
Filip Gorachinov, Fatima Mraiche, Diala Alhaj Moustafa, Ola Hishari, Yomna Ismail, Jensa Joseph, Maja Simonoska Crcarevska, Marija Glavas Dodov, Nikola Geskovski & Katerina Goracinova. (2023) Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer. Beilstein Journal of Nanotechnology 14, pages 240-261.
Crossref
Oluwakemi Ebenezer, Pietro Comoglio, Gane Ka-Shu Wong & Jack A. Tuszynski. (2023) Development of Novel siRNA Therapeutics: A Review with a Focus on Inclisiran for the Treatment of Hypercholesterolemia. International Journal of Molecular Sciences 24:4, pages 4019.
Crossref
Suleiman Alhaji Muhammad, Mohammed Sani Jaafaru & Sulaiman Rabiu. (2023) A Meta-analysis on the Effectiveness of Extracellular Vesicles as Nanosystems for Targeted Delivery of Anticancer Drugs. Molecular Pharmaceutics 20:2, pages 1168-1188.
Crossref
Tianqi Wang, Hongqi Zhao, Shaoze Jing, Yang Fan, Gaohong Sheng, Qing Ding, Chaoxu Liu, Hua Wu & Yang Liu. (2023) Magnetofection of miR-21 promoted by electromagnetic field and iron oxide nanoparticles via the p38 MAPK pathway contributes to osteogenesis and angiogenesis for intervertebral fusion. Journal of Nanobiotechnology 21:1.
Crossref
Sayed S. Sohrab, Sherif A. El-Kafrawy, Zeenat Mirza, Ahmed M. Hassan, Fatima Alsaqaf & Esam I. Azhar. (2023) Computational Design and Experimental Evaluation of MERS-CoV siRNAs in Selected Cell Lines. Diagnostics 13:1, pages 151.
Crossref
Pier-Luc Clermont. (2023) Epigenetics-based diagnostic and therapeutic strategies: shifting the paradigm in prostate cancer. Epigenomics 15:2, pages 75-87.
Crossref
Homa Fatma & Hifzur R. Siddique. 2023. Regulation of Downstream Targets. Regulation of Downstream Targets 115 145 .
Vandana Vinayak, Mohd Jahir Khan & Khasthi Ballabh Joshi. 2023. Applications of Multifunctional Nanomaterials. Applications of Multifunctional Nanomaterials 95 124 .
Mehdi Afrouz, Amin Amani, Ali Eftekhari, Christophe Coudret, Sabry G. Elias, Zainab Ahmadian & Mohammad Taghi Alebrahim. (2022) Design and synthesis of multi-targeted nanoparticles for gene delivery to breast cancer tissues. Naunyn-Schmiedeberg's Archives of Pharmacology 396:1, pages 121-137.
Crossref
Mohammad Qasim Andrabi, Ilangovan Ramachandran, R. Ileng Kumaran & Satish Ramalingam. 2023. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 875 892 .
Mohammad Qasim Andrabi, Ilangovan Ramachandran, R. Ileng Kumaran & Satish Ramalingam. 2022. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 1 18 .
Kailing Lu, Qijing Fan & Xiaoju Zou. (2022) Antisense oligonucleotide is a promising intervention for liver diseases. Frontiers in Pharmacology 13.
Crossref
Dokkari Nagalaxmi Yadav, Mohammad Sadik Ali, Ajinkya Madhukar Thanekar, Sunil Venkanna Pogu & Aravind Kumar Rengan. (2022) Recent Advancements in the Design of Nanodelivery Systems of siRNA for Cancer Therapy. Molecular Pharmaceutics 19:12, pages 4506-4526.
Crossref
Shuiliang Yu, Lei Wang, Danian Che, Mei Zhang, Ming Li, Mikihiko Naito, Wei Xin & Lan Zhou. (2022) Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling. Journal of Experimental & Clinical Cancer Research 41:1.
Crossref
Ananya Pattnaik, Swarnaparabha Pany, A. S. Sanket, Sudiptee Das, Sanghamitra Pati & Sangram K. Samal. 2022. Targeted Drug Delivery. Targeted Drug Delivery 221 246 .
Cristina de la Torre, Pablo Játiva, Inmaculada Posadas, Darío Manzanares, José L. Jiménez Blanco, Carmen Ortiz Mellet, José Manuel García Fernández & Valentín Ceña. (2022) A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells. Pharmaceutics 14:11, pages 2424.
Crossref
Krishna Yadav, Deependra Singh, Manju Rawat Singh & Madhulika Pradhan. (2022) Nano-constructs targeting the primary cellular energy source of cancer cells for modulating tumor progression. OpenNano 8, pages 100107.
Crossref
Sara Adibfar, Ali Masjedi, Atefeh Nazer, Bentolhoda Rashidi, Vahid Karpisheh, Sepideh Izadi, Hadi Hassannia, Jamshid Gholizadeh Navashenaq, Hamed Mohammadi, Mohammad Hojjat-Farsangi, Hanieh Tarokhian & Farhad Jadidi-Niaragh. (2022) Combined inhibition of EZH2 and CD73 molecules by folic acid-conjugated SPION-TMC nanocarriers loaded with siRNA molecules prevents TNBC progression and restores anti-tumor responses. Life Sciences 309, pages 121008.
Crossref
Betul Celik, Kader Cicek, Andrés Felipe Leal & Shunji Tomatsu. (2022) Regulation of Molecular Targets in Osteosarcoma Treatment. International Journal of Molecular Sciences 23:20, pages 12583.
Crossref
Franck Marquet, Filip Stojceski, Gianvito Grasso, Viorica Patrulea, Andrea Danani & Gerrit Borchard. (2022) Characterization of the Interaction of Polymeric Micelles with siRNA: A Combined Experimental and Molecular Dynamics Study. Polymers 14:20, pages 4409.
Crossref
Devaraj Ezhilarasan, Thangavelu Lakshmi & Sreekanth Kumar Mallineni. (2022) Nano-based targeted drug delivery for lung cancer: therapeutic avenues and challenges. Nanomedicine 17:24, pages 1855-1869.
Crossref
Dibyashree Chhetri, Srinivasan Vengadassalapathy, Santhosh Venkadassalapathy, Varadharaju Balachandran, Vidhya Rekha Umapathy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Shankargouda Patil, Ashok Iyaswamy, Kanagaraj Palaniyandi & Dhanavathy Gnanasampanthapandian. (2022) Pleiotropic effects of DCLK1 in cancer and cancer stem cells. Frontiers in Molecular Biosciences 9.
Crossref
Sankha Bhattacharya, Dnyanesh Saindane & Bhupendra G. Prajapati. (2022) Liposomal Drug Delivery and Its Potential Impact on Cancer Research. Anti-Cancer Agents in Medicinal Chemistry 22:15, pages 2671-2683.
Crossref
Shiva Kamran, Ensiyeh Seyedrezazadeh, Dariush Shanehbandi, Milad Asadi, Venus Zafari, Najibeh Shekari, Leila Namvar & Habib Zarredar. (2021) Combination Therapy with KRAS and P38α siRNA Suppresses Colorectal Cancer Growth and Development in SW480 Cell Line. Journal of Gastrointestinal Cancer 53:3, pages 597-604.
Crossref
Mortaza Raeisi, Leila Hassanbeigi, Fatemeh Khalili, Hengameh Kharrati-Shishavan, Mehdi Yousefi & Amir Mehdizadeh. (2022) Stearoyl-CoA desaturase 1 as a therapeutic target for cancer: a focus on hepatocellular carcinoma. Molecular Biology Reports 49:9, pages 8871-8882.
Crossref
Maja Houseman, Melody Ying‐Yu Huang, Markus Huber, Matthias Staiger, Lan Zhang, Anneliese Hoffmann, Christoph Lippuner & Frank Stüber. (2022) Flow cytometry‐based high‐throughput RNAi screening for miRNAs regulating MHC class II HLA‐DR surface expression. European Journal of Immunology 52:9, pages 1452-1463.
Crossref
Simran Nasra, Dhiraj Bhatia & Ashutosh Kumar. (2022) Recent advances in nanoparticle-based drug delivery systems for rheumatoid arthritis treatment. Nanoscale Advances 4:17, pages 3479-3494.
Crossref
Calin Nicolescu, Amita Vaidya, Andrew Schilb & Zheng-Rong Lu. (2022) Regulating Oncogenic LncRNA DANCR with Targeted ECO/siRNA Nanoparticles for Non-Small Cell Lung Cancer Therapy. ACS Omega 7:26, pages 22743-22753.
Crossref
Reda Ben Mrid, Najat Bouchmaa, Hassan Ainani, Rachid El Fatimy, Gabriel Malka & Loubna Mazini. (2022) Anti-rheumatoid drugs advancements: New insights into the molecular treatment of rheumatoid arthritis. Biomedicine & Pharmacotherapy 151, pages 113126.
Crossref
Jelter Van Hoeck, Kevin Braeckmans, Stefaan C. De Smedt & Koen Raemdonck. (2022) Non-viral siRNA delivery to T cells: Challenges and opportunities in cancer immunotherapy. Biomaterials 286, pages 121510.
Crossref
Ganesh Kumar Barik, Osheen Sahay, Debasish Paul & Manas Kumar Santra. (2022) Ezrin gone rogue in cancer progression and metastasis: An enticing therapeutic target. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:4, pages 188753.
Crossref
Swaroop Kumar Pandey, Renen Machlof-Cohen, Manikandan Santhanam, Anna Shteinfer-Kuzmine & Varda Shoshan-Barmatz. (2022) Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks. Biomolecules 12:7, pages 895.
Crossref
Yamin Li, Zhongfeng Ye, Hanyi Yang & Qiaobing Xu. (2022) Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs. Acta Pharmaceutica Sinica B 12:6, pages 2624-2639.
Crossref
Nadia M. Hamdy, Fatma H. Shaker, Xianquan Zhan & Emad B. Basalious. (2022) Tangled quest of post-COVID-19 infection-caused neuropathology and what 3P nano-bio-medicine can solve?. EPMA Journal 13:2, pages 261-284.
Crossref
Indra Rautela, Aditi Sharma, Pallavi Dheer, Priya Thapliyal, Shweta Sahni, Vimlendu Bhushan Sinha & Manish Dev Sharma. (2021) Extension in the approaches to treat cancer through siRNA system: a beacon of hope in cancer therapy. Drug Delivery and Translational Research 12:5, pages 1002-1016.
Crossref
Carme Fàbrega, Anna Aviñó & Ramon Eritja. (2021) Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications. The Chemical Record 22:4.
Crossref
Yeon Jeong Yoo, Chang Hoon Lee, Sei Hyun Park & Yong Taik Lim. (2022) Nanoparticle-based delivery strategies of multifaceted immunomodulatory RNA for cancer immunotherapy. Journal of Controlled Release 343, pages 564-583.
Crossref
Hend A.A. Abd El-wahab, Hany S. Mansour, Ahmed M. Ali, Raafat El-Awady & Tarek Aboul-Fadl. (2022) New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorganic Chemistry 120, pages 105622.
Crossref
Namita Mahadik, Dwaipayan Bhattacharya, Akshaya Padmanabhan, Kalyani Sakhare, Kumar Pranav Narayan & Rajkumar Banerjee. (2021) Targeting steroid hormone receptors for anti‐cancer therapy—A review on small molecules and nanotherapeutic approaches. WIREs Nanomedicine and Nanobiotechnology 14:2.
Crossref
Yuan Zhang, Juhura G. Almazi, Hui Xin Ong, Matt D. Johansen, Scott Ledger, Daniela Traini, Philip M. Hansbro, Anthony D. Kelleher & Chantelle L. Ahlenstiel. (2022) Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract. International Journal of Molecular Sciences 23:5, pages 2408.
Crossref
Ali Alazzo, Nurcan Gumus, Pratik Gurnani, Snjezana Stolnik, Ruman Rahman, Keith Spriggs & Cameron Alexander. (2022) Investigating histidinylated highly branched poly(lysine) for siRNA delivery. Journal of Materials Chemistry B 10:2, pages 236-246.
Crossref
Jiajia Chen, Yang Yang, Bingquan Lin, Zexian Xu, Xi Yang, Shaoguang Ye, Zhaoxiong Xie, Yanbing Li, Jianwen Hong, Zehai Huang & Wenhua Huang. (2022) Hollow mesoporous organosilica nanotheranostics incorporating formimidoyltransferase cyclodeaminase (FTCD) plasmids for magnetic resonance imaging and tetrahydrofolate metabolism fission on hepatocellular carcinoma. International Journal of Pharmaceutics 612, pages 121281.
Crossref
Negar Bidar, Majid Darroudi, Ailin Ebrahimzadeh, Mohammadreza Safdari, Miguel de la Guardia, Behzad Baradaran, Vahabodin Goodarzi, Fatemeh Oroojalian & Ahad Mokhtarzadeh. (2022) Simultaneous nanocarrier-mediated delivery of siRNAs and chemotherapeutic agents in cancer therapy and diagnosis: Recent advances. European Journal of Pharmacology 915, pages 174639.
Crossref
Krishan Kumar, Varsha Rani, Mohini Mishra & Ruchi Chawla. (2022) New paradigm in combination therapy of siRNA with chemotherapeutic drugs for effective cancer therapy. Current Research in Pharmacology and Drug Discovery 3, pages 100103.
Crossref
Mohammad Qasim Andrabi, Ilangovan Ramachandran, R. Ileng Kumaran & Satish Ramalingam. 2022. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 1 18 .
Valentina Uivarosi, Alexandra-Cristina Munteanu, Mihaela Badea & Rodica Olar. 2022. Plant Secondary Metabolites. Plant Secondary Metabolites 281 327 .
Nishat Tabassum, Shoeb Ahmed & M. Azam Ali. 2022. Chitooligosaccharides. Chitooligosaccharides 309 332 .
Teruaki Tozaki, Ho‐Geun Kwak, Kotono Nakamura, Masaki Takasu, Hideaki Ishii, Aoi Ohnuma, Mio Kikuchi, Taichiro Ishige, Hironaga Kakoi, Kei‐ichi Hirota, Kanichi Kusano, Minoru Hirata, Takashi Nirasawa & Shun‐ichi Nagata. (2021) Sequence determination of phosphorothioated oligonucleotides using MALDI‐TOF mass spectrometry for controlling gene doping in equestrian sports. Drug Testing and Analysis 14:1, pages 175-180.
Crossref
Anjaly Rajeev, Aiswarya Siby, Merin James Koottungal, Jinu George & Franklin John. (2021) Knocking Down Barriers: Advances in siRNA Delivery. ChemistrySelect 6:46, pages 13350-13362.
Crossref
Chhavi Choudhary, Keshav Kumar Meghwanshi, Nidhi Shukla & Jayendra Nath Shukla. (2021) Innate and adaptive resistance to RNAi: a major challenge and hurdle to the development of double stranded RNA-based pesticides. 3 Biotech 11:12.
Crossref
Maria Arista-Romero, Anna Cascante, Cristina Fornaguera & Salvador Borrós. (2021) Role of Survivin in Bladder Cancer: Issues to Be Overcome When Designing an Efficient Dual Nano-Therapy. Pharmaceutics 13:11, pages 1959.
Crossref
Dmitriy Berillo, Adilkhan Yeskendir, Zharylkasyn Zharkinbekov, Kamila Raziyeva & Arman Saparov. (2021) Peptide-Based Drug Delivery Systems. Medicina 57:11, pages 1209.
Crossref
Komal Abhange, Amy Makler, Yi Wen, Natasha Ramnauth, Wenjun Mao, Waseem Asghar & Yuan Wan. (2021) Small extracellular vesicles in cancer. Bioactive Materials 6:11, pages 3705-3743.
Crossref
Yuebao Zhang, Changzhen Sun, Chang Wang, Katarina E. Jankovic & Yizhou Dong. (2021) Lipids and Lipid Derivatives for RNA Delivery. Chemical Reviews 121:20, pages 12181-12277.
Crossref
Jingru Xu, Mengjie Gu, Lissa Hooi, Tan Boon Toh, Dexter Kai Hao Thng, Jhin Jieh Lim & Edward Kai-Hua Chow. (2021) Enhanced penetrative siRNA delivery by a nanodiamond drug delivery platform against hepatocellular carcinoma 3D models. Nanoscale 13:38, pages 16131-16145.
Crossref
Mengyao Chen, Chunyan Dong & Shuo Shi. (2021) Nanoparticle‐Mediated siRNA Delivery and Multifunctional Modification Strategies for Effective Cancer Therapy. Advanced Materials Technologies 6:10, pages 2001236.
Crossref
Vivek Patel, Denish Bardoliwala, Rohan Lalani, Sushilkumar Patil, Saikat Ghosh, Ankit Javia & Ambikanandan Misra. (2021) Development of a dry powder for inhalation of nanoparticles codelivering cisplatin and ABCC3 siRNA in lung cancer . Therapeutic Delivery 12:9, pages 651-670.
Crossref
Jinghuan Huang, Muyu Yu, Wenjing Yin, Bo Liang, Ang Li, Jingfeng Li, Xiaolin Li, Shichang Zhao & Fang Liu. (2021) Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds. Bioactive Materials 6:9, pages 2841-2853.
Crossref
Jianlei Xie, Yingwei Wang, Wonseok Choi, Paramesh Jangili, Yanqi Ge, Yunjie Xu, Jianlong Kang, Liping Liu, Bin Zhang, Zhongjian Xie, Jun He, Ni Xie, Guohui Nie, Han Zhang & Jong Seung Kim. (2021) Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies. Chemical Society Reviews 50:16, pages 9152-9201.
Crossref
Sarwar Beg, Waleed H. Almalki, Fahmida Khatoon, Khalid S. Alharbi, Saad Alghamdi, Md. Habban Akhter, Habibullah Khalilullah, Abdullah A. Baothman, Abdul Hafeez, Mahfoozur Rahman, Sohail Akhter & Hani Choudhry. (2021) Lipid/polymer-based nanocomplexes in nucleic acid delivery as cancer vaccines. Drug Discovery Today 26:8, pages 1891-1903.
Crossref
Xiaodan Wang, Kangkai Zheng, Wenyu Cheng, Jie Li, Xiangxiu Liang, Jie Shen, Daolong Dou, Meizhen Yin & Shuo Yan. (2021) Field application of star polymer-delivered chitosan to amplify plant defense against potato late blight. Chemical Engineering Journal 417, pages 129327.
Crossref
Akshita Chauhan, Tabassum Khan & Abdelwahab Omri. (2021) Design and Encapsulation of Immunomodulators onto Gold Nanoparticles in Cancer Immunotherapy. International Journal of Molecular Sciences 22:15, pages 8037.
Crossref
Andreea Crintea, Alina Gabriela Dutu, Gabriel Samasca, Ioan Alexandru Florian, Iulia Lupan & Alexandra Marioara Craciun. (2021) The Nanosystems Involved in Treating Lung Cancer. Life 11:7, pages 682.
Crossref
Ya Liu, Changhong Zhao, Alan Sabirsh, Lilei Ye, Xiaoqiu Wu, Hongbin Lu & Johan Liu. (2021) A Novel Graphene Quantum Dot‐Based mRNA Delivery Platform. ChemistryOpen 10:7, pages 666-671.
Crossref
Cheng Yu, Long Li, Pei Hu, Yan Yang, Wei Wei, Xin Deng, Lu Wang, Franklin R. Tay & Jingzhi Ma. (2021) Recent Advances in Stimulus‐Responsive Nanocarriers for Gene Therapy. Advanced Science 8:14.
Crossref
Elham Bidram, Yasaman Esmaeili, Abbas Amini, Rossella Sartorius, Franklin R. Tay, Laleh Shariati & Pooyan Makvandi. (2021) Nanobased Platforms for Diagnosis and Treatment of COVID-19: From Benchtop to Bedside. ACS Biomaterials Science & Engineering 7:6, pages 2150-2176.
Crossref
Guruprasadh Swaminathan, Aisha Shigna, Aviral Kumar, Vishnu Vardhan Byroju, Varsha Reddy Durgempudi & Lekha Dinesh Kumar. (2021) RNA Interference and Nanotechnology: A Promising Alliance for Next Generation Cancer Therapeutics. Frontiers in Nanotechnology 3.
Crossref
Jia-shuai He, Shi-jin Liu, Yi-ran Zhang, Xiao-dong Chu, Zheng-bin Lin, Zhan Zhao, Sheng-hui Qiu, Yan-guan Guo, Hui Ding, Yun-long Pan & Jing-hua Pan. (2021) The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy. Frontiers in Pharmacology 12.
Crossref
M. Khodaei, K. Rostamizadeh, A. H. Taromchi, H. Monirinasab & M. Fathi. (2021) DDAB cationic lipid-mPEG, PCL copolymer hybrid nano-carrier synthesis and application for delivery of siRNA targeting IGF-1R into breast cancer cells. Clinical and Translational Oncology 23:6, pages 1167-1178.
Crossref
Sanaz Naghibi, Tong Chen, Amin Jamshidi Ghahfarokhi & Youhong Tang. (2021) AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms. Aggregate 2:3.
Crossref
Mohd Ahmar Rauf, Munazzah Tasleem, Ketki Bhise, Katyayani Tatiparti, Samaresh Sau & Arun K. Iyer. (2021) Nano‐therapeutic strategies to target coronavirus. VIEW 2:3, pages 20200155.
Crossref
Moolchand Kurmi, Vipul Suryavanshi, Narayana Swamy Panduranga, Karthik Jayaraman, Lakshmikant Bajpai, William Fish, Yue Hu & Hemant Bhutani. (2021) Development of HPLC-CAD stability indicating assay method for polyethylene glycol-conjugated phospholipid (DMPE-PEG 2000) and identification of its degradation products. Journal of Pharmaceutical and Biomedical Analysis 198, pages 113967.
Crossref
Farshad Mirzavi, Mehdi Barati, Anvar Soleimani, Roghayyeh Vakili-Ghartavol, Mahmoud Reza Jaafari & Mohammad Soukhtanloo. (2021) A review on liposome-based therapeutic approaches against malignant melanoma. International Journal of Pharmaceutics 599, pages 120413.
Crossref
Haoyu Xiong, Rakesh N. Veedu & Sarah D. Diermeier. (2021) Recent Advances in Oligonucleotide Therapeutics in Oncology. International Journal of Molecular Sciences 22:7, pages 3295.
Crossref
Zhili Tian, Guohui Liang, Kunli Cui, Yayu Liang, Qun Wang, Shuangyu Lv, Xiaoxia Cheng & Lei Zhang. (2021) Insight Into the Prospects for RNAi Therapy of Cancer. Frontiers in Pharmacology 12.
Crossref
Banendu Sunder Dash, Gils Jose, Yu-Jen Lu & Jyh-Ping Chen. (2021) Functionalized Reduced Graphene Oxide as a Versatile Tool for Cancer Therapy. International Journal of Molecular Sciences 22:6, pages 2989.
Crossref
Dongyu Chen, Shanthi Ganesh, Weimin Wang, Adrien Lupieri & Mansoor Amiji. (2021) Role of vitronectin-rich protein corona on tumor-specific siRNA delivery and transfection with lipid nanoparticles. Nanomedicine 16:7, pages 535-551.
Crossref
Rashmi Rana, Shikha Joon, Kirti Chauhan, Vaishnavi Rathi, Nirmal Kumar Ganguly, Chandni Kumari & Dharmendra Kumar Yadav. (2021) Role of Extracellular Vesicles in Glioma Progression: Deciphering Cellular Biological Processes to Clinical Applications. Current Topics in Medicinal Chemistry 21:8, pages 696-704.
Crossref
Vignesh Kumar, Sairam Yadavilli & Raghuraman Kannan. (2020) A review on RNAi therapy for NSCLC : Opportunities and challenges . WIREs Nanomedicine and Nanobiotechnology 13:2.
Crossref
Zheng‐Rong Lu, Victoria E. A. Laney, Ryan Hall & Nadia Ayat. (2020) Environment‐Responsive Lipid/siRNA Nanoparticles for Cancer Therapy. Advanced Healthcare Materials 10:5.
Crossref
Erdal Eroğlu, Hüseyin Saygın Portakal & Ayşenur Pamukçu. (2021) A New Generation Nanotherapeutic: pHEMA-Chitosan Nanocomposites in siRNA Delivery. Current Nanoscience 16:6, pages 880-889.
Crossref
Shuo Yan, Bin‐Yuan Ren & Jie Shen. (2020) Nanoparticle‐mediated double‐stranded RNA delivery system: A promising approach for sustainable pest management. Insect Science 28:1, pages 21-34.
Crossref
Zeenat Mirza & Sajjad Karim. (2021) Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges. Seminars in Cancer Biology 69, pages 226-237.
Crossref
Hanieh Mousazadeh, Younes Pilehvar-Soltanahmadi, Mehdi Dadashpour & Nosratollah Zarghami. (2021) Cyclodextrin based natural nanostructured carbohydrate polymers as effective non-viral siRNA delivery systems for cancer gene therapy. Journal of Controlled Release 330, pages 1046-1070.
Crossref
Shalini Sakthivel, Manjita Srivastava, Muneesh Kumar Barman, Nerethika Ravichandiran, Salonee Martins, Meenakshi Singh, Kailash Chand, Subash C. Sonkar & Prudhvilal Bhukya. 2021. Handbook of Research on Advancements in Cancer Therapeutics. Handbook of Research on Advancements in Cancer Therapeutics 486 513 .
Ewa Jablonska, Qi Li, Edyta Reszka, Edyta Wieczorek, Kateryna Tarhonska & Tong Wang. (2021) Therapeutic Potential of Selenium and Selenium Compounds in Cervical Cancer. Cancer Control 28, pages 107327482110018.
Crossref
Zhian Chen, Yanrui Liang, Xiaoli Feng, Yu Liang, Guodong Shen, Huilin Huang, Zhaoyu Chen, Jiang Yu, Hao Liu, Tian Lin, Hao Chen, Dong Wu, Guoxin Li, Bingxia Zhao, Weihong Guo & Yanfeng Hu. (2021) Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer. Materials Science and Engineering: C 120, pages 111722.
Crossref
Si-Yue Tang, Hua Wei & Cui-Yun Yu. (2021) Peptide-functionalized delivery vehicles for enhanced cancer therapy. International Journal of Pharmaceutics 593, pages 120141.
Crossref
Devaraj Ezhilarasan & Roy Anitha. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 217 223 .
Farrukh Zeeshan. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 461 466 .
Tigran Harutyunyan & Galina Hovhannisyan. 2021. Cytogenomics. Cytogenomics 155 209 .
Shahid Karim, Wei Meng Lim, Farrukh Zeeshan, Huda M. Alkreathy, Nabil A. Alhakamy, Hibah M. Aldawsari & Shadab Md. 2021. Nanocarriers for the Delivery of Combination Drugs. Nanocarriers for the Delivery of Combination Drugs 307 335 .
Mehdi Ebrahimi. 2021. Early Detection and Treatment of Head & Neck Cancers. Early Detection and Treatment of Head & Neck Cancers 63 120 .
Goknur Kara, Ayhan Parlar, Melike Cokol Cakmak, Murat Cokol, Emir Baki Denkbas & Feray Bakan. (2020) Silencing of survivin and cyclin B1 through siRNA-loaded arginine modified calcium phosphate nanoparticles for non-small-cell lung cancer therapy. Colloids and Surfaces B: Biointerfaces 196, pages 111340.
Crossref
Ata Ullah, Javaria Qazi, Lutfur Rahman, Antonios G. Kanaras, Waheed S. Khan, Irshad Hussain & Asma Rehman. (2020) Nanoparticles‐assisted delivery of antiviral‐siRNA as inhalable treatment for human respiratory viruses: A candidate approach against SARS‐COV‐2. Nano Select 1:6, pages 612-621.
Crossref
Jiji V. D. Attia, Charlotte E. Dessens, Ricky van de Water, Ruben D. Houvast, Peter J. K. Kuppen & Daniëlle Krijgsman. (2020) The Molecular and Functional Characteristics of HLA-G and the Interaction with Its Receptors: Where to Intervene for Cancer Immunotherapy?. International Journal of Molecular Sciences 21:22, pages 8678.
Crossref
Ankur Sharma, Niraj Kumar Jha, Kajal Dahiya, Vivek Kumar Singh, Kundan Chaurasiya, Aditya Narayan Jha, Saurabh Kumar Jha, Prabhu Chandra Mishra, Sunny Dholpuria, Rani Astya, Parma Nand, Amit Kumar, Janne Ruokolainen & Kavindra Kumar Kesari. (2020) Nanoparticulate RNA delivery systems in cancer. Cancer Reports 3:5.
Crossref
Ilaria Proietti, Nevena Skroza, Nicoletta Bernardini, Ersilia Tolino, Veronica Balduzzi, Anna Marchesiello, Simone Michelini, Salvatore Volpe, Alessandra Mambrin, Giorgio Mangino, Giovanna Romeo, Patrizia Maddalena, Catherine Rees & Concetta Potenza. (2020) Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review. Cancers 12:10, pages 2801.
Crossref
Behrooz Johari, Hamed Rezaeejam, Mohammad Moradi, Zahraa Taghipour, Zohreh Saltanatpour, Yousef Mortazavi & Leila Nasehi. (2020) Increasing the colon cancer cells sensitivity toward radiation therapy via application of Oct4–Sox2 complex decoy oligodeoxynucleotides. Molecular Biology Reports 47:9, pages 6793-6805.
Crossref
Nan Gao, Fangzhou Shi, Dandan Song & Wei Xuan. (2020) The roles of exosomal circular RNAs in cancer . IUBMB Life 72:9, pages 1909-1919.
Crossref
Natalia Sanz del Olmo, Marcin Holota, Sylwia Michlewska, Rafael Gómez, Paula Ortega, Maksim Ionov, Francisco Javier de la Mata & Maria Bryszewska. (2020) Copper (II) Metallodendrimers Combined with Pro-Apoptotic siRNAs as a Promising Strategy Against Breast Cancer Cells. Pharmaceutics 12:8, pages 727.
Crossref
Mariam Mroweh, Thomas Decaens, Patrice N Marche, Zuzana Macek Jilkova & Flora Clément. (2020) Modulating the Crosstalk between the Tumor and Its Microenvironment Using RNA Interference: A Treatment Strategy for Hepatocellular Carcinoma. International Journal of Molecular Sciences 21:15, pages 5250.
Crossref
Karishma Dhuri, Clara Bechtold, Elias Quijano, Ha Pham, Anisha Gupta, Ajit Vikram & Raman Bahal. (2020) Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development. Journal of Clinical Medicine 9:6, pages 2004.
Crossref
Sara C. Humphreys, Mai B. Thayer, Jabbar Campbell, Wen Li Kelly Chen, Dan Adams, Julie M. Lade & Brooke M. Rock. (2020) Emerging siRNA Design Principles and Consequences for Biotransformation and Disposition in Drug Development. Journal of Medicinal Chemistry 63:12, pages 6407-6422.
Crossref
Qi Chang Zheng, Shuai Jiang, Yu Zhe Wu, Dan Shang, Yong Zhang, Shao Bo Hu, Xiang Cheng, Chen Zhang, Ping Sun, Yang Gao, Zi Fang Song & Min Li. (2020) Dual-Targeting Nanoparticle-Mediated Gene Therapy Strategy for Hepatocellular Carcinoma by Delivering Small Interfering RNA. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Yunfeng Lin, Zhuo Chen, Chaohua Hu, Zhe-Sheng Chen & Lei Zhang. (2020) Recent progress in antitumor functions of the intracellular antibodies. Drug Discovery Today 25:6, pages 1109-1120.
Crossref
Vida Hashemi, Armin Ahmadi, Farinaz Malakotikhah, Mitra Ghasemi Chaleshtari, Mahdi Baghi Moornani, Ali Masjedi, Mozhdeh Sojoodi, Fatemeh Atyabi, Afshin Nikkhoo, Narges Rostami, Behzad Baradaran, Gholamreza Azizi, Bahman Yousefi, Ghasem Ghalamfarsa & Farhad Jadidi-Niaragh. (2020) Silencing of p68 and STAT3 synergistically diminishes cancer progression. Life Sciences 249, pages 117499.
Crossref
Zhuohao Liu, Ruixiang Ge, Jiayi Zhou, Xinzhi Yang, Kenneth King-yip Cheng, Jingli Tao, Dinglan Wu & Jie Mao. (2020) Nuclear factor IX promotes glioblastoma development through transcriptional activation of Ezrin. Oncogenesis 9:4.
Crossref
Nan Zhou & Jinku Bao. (2020) RNAdt: An online tutorial and data portal for the RNA structurome era. Biosystems 189, pages 104065.
Crossref
Christelle Zandanel, Magali Noiray & Christine Vauthier. (2020) Counterion of Chitosan Influences Thermodynamics of Association of siRNA with a Chitosan-Based siRNA Carrier. Pharmaceutical Research 37:2.
Crossref
Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohammadinejad, Tahereh Farkhondeh & Saeed Samarghandian. (2020) Nano-soldiers Ameliorate Silibinin Delivery: A Review Study. Current Drug Delivery 17:1, pages 15-22.
Crossref
Shalini Jain, Neha Saxena, Mukesh Kumar Sharma & Sreemoyee Chatterjee. (2020) Metal nanoparticles and medicinal plants: Present status and future prospects in cancer therapy. Materials Today: Proceedings 31, pages 662-673.
Crossref
Perla Pucci, Wallace Yuen, Erik Venalainen, David Roig Carles, Yuzhuo Wang & Francesco Crea. 2020. The Chemical Biology of Long Noncoding RNAs. The Chemical Biology of Long Noncoding RNAs 167 198 .
Adil Malik, Srilakshmi Srinivasan & Jyotsna Batra. (2019) A New Era of Prostate Cancer Precision Medicine. Frontiers in Oncology 9.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.