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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

A dual-functional HER2 aptamer-conjugated, pH-activated mesoporous silica nanocarrier-based drug delivery system provides in vitro synergistic cytotoxicity in HER2-positive breast cancer cells

Yinxing Shen1 Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai200237, People’s Republic of China;2 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai200032, People’s Republic of China
,
Mengya Li1 Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai200237, People’s Republic of China
,
Tianqi Liu1 Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai200237, People’s Republic of China
,
Jing Liu2 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai200032, People’s Republic of China
,
Youhua Xie2 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai200032, People’s Republic of China
,
Junqi Zhang2 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai200032, People’s Republic of ChinaCorrespondence[email protected]
,
Shouhong Xu1 Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai200237, People’s Republic of ChinaCorrespondence[email protected]
&
Honglai Liu1 Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai200237, People’s Republic of China
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Pages 4029-4044 | Published online: 31 May 2019

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Yadollah Omidi, Maha Mobasher, Ana M. Castejon & Morteza Mahmoudi. (2022) Recent advances in nanoscale targeted therapy of HER2-positive breast cancer. Journal of Drug Targeting 30:7, pages 687-708.
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Cheng-Wu Zhang, Jun-Gang Zhang, Xue Yang, Wen-Lin Du, Zi-Lin Yu, Zhen-Ye Lv & Xiao-Zhou Mou. (2022) Carbohydrates based stimulus responsive nanocarriers for cancer-targeted chemotherapy: a review of current practices. Expert Opinion on Drug Delivery 19:6, pages 623-640.
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Sahar Porrang, Soodabeh Davaran, Nader Rahemi, Somaiyeh Allahyari & Ebrahim Mostafavi. (2022) How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature. International Journal of Nanomedicine 17, pages 1803-1827.
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Haocheng Qin, Rong Teng, Yan Liu, Juan Li & Ming Yu. (2022) Drug Release from Gelsolin-Targeted Phase-Transition Nanoparticles Triggered by Low-Intensity Focused Ultrasound. International Journal of Nanomedicine 17, pages 61-71.
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Jialang Zhuang, Siqi Chen, Ye Hu, Fan Yang, Qin Huo & Ni Xie. (2021) RETRACTED ARTICLE: Tumour-Targeted and Redox-Responsive Mesoporous Silica Nanoparticles for Controlled Release of Doxorubicin and an siRNA Against Metastatic Breast Cancer. International Journal of Nanomedicine 16, pages 1961-1976.
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Ruifeng Wu, Zhiqiang Zhang, Baohua Wang, Ge Chen, Yaozhong Zhang, Haowen Deng, Zilong Tang, Junjie Mao & Lei Wang. (2020) Combination Chemotherapy of Lung Cancer – Co-Delivery of Docetaxel Prodrug and Cisplatin Using Aptamer-Decorated Lipid–Polymer Hybrid Nanoparticles. Drug Design, Development and Therapy 14, pages 2249-2261.
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Jian Lin, Zhiqi He, Fen Liu, Jie Feng, Chengyi Huang, Xueli Sun & Hui Deng. (2020) Hybrid Hydrogels for Synergistic Periodontal Antibacterial Treatment with Sustained Drug Release and NIR-Responsive Photothermal Effect. International Journal of Nanomedicine 15, pages 5377-5387.
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