Advanced search
Publication Cover
International Journal of Nanomedicine Volume 14, 2019 - Issue
Submit an article Journal homepage
350
Views
59
CrossRef citations to date
0
Altmetric
Original Research

Enzyme-responsive mesoporous silica nanoparticles for tumor cells and mitochondria multistage-targeted drug delivery

Safia Naz1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
,
Mingyu Wang1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
,
Yuning Han1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
,
Bin Hu1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
,
Liping Teng2 Wuxi School of Medicine, Jiangnan University, Wuxi, People’s Republic of China
,
Juan Zhou1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of ChinaCorrespondence[email protected] [email protected]
,
Huijie Zhang1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
&
Jinghua Chen1 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, People’s Republic of China
 show all
Pages 2533-2542 | Published online: 10 Apr 2019

Citations (59)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Taishi Yokoi, Akiyoshi Mio, Jin Nakamura, Ayae Sugawara-Narutaki, Masakazu Kawashita & Chikara Ohtsuki. (2022) Transformation behaviour of salts composed of calcium ions and phosphate esters with different linear alkyl chain structures in a simulated body fluid modified with alkaline phosphatase. Science and Technology of Advanced Materials 23:1, pages 341-351.
Read now
Muhammad Umair Amin, Sajid Ali, Muhammad Yasir Ali, Dominik C. Fuhrmann, Imran Tariq, Benjamin S. Seitz, Eduard Preis, Jana Brüßler, Bernhard Brüne & Udo Bakowsky. (2022) Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance. Drug Delivery 29:1, pages 2072-2085.
Read now
Mohsen Ghaferi, Maedeh Koohi Moftakhari Esfahani, Aun Raza, Sitah Al Harthi, Hasan Ebrahimi Shahmabadi & Seyed Ebrahim Alavi. (2021) Mesoporous silica nanoparticles: synthesis methods and their therapeutic use-recent advances. Journal of Drug Targeting 29:2, pages 131-154.
Read now
Niloufar Maghsoudnia, Reza Baradaran Eftekhari, Alireza Naderi Sohi, Parisa Norouzi, Hamid Akbari, Mohammad Hossein Ghahremani, Masoud Soleimani, Mohsen Amini, Hamed Samadi & Farid Abedin Dorkoosh. (2020) Mitochondrial delivery of microRNA mimic let-7b to NSCLC cells by PAMAM-based nanoparticles. Journal of Drug Targeting 28:7-8, pages 818-830.
Read now

Articles from other publishers (55)

Vaishali Pawar, Priyanka Maske, Amreen Khan, Arnab Ghosh, Roshan Keshari, Mahek Bhatt & Rohit Srivastava. (2023) Responsive Nanostructure for Targeted Drug Delivery. Journal of Nanotheranostics 4:1, pages 55-85.
Crossref
Yijun Wu, Zhiqiang Sun, Jinfeng Song, Liufang Mo, Xiaochen Wang, Hanhan Liu & Yunfeng Ma. (2022) Preparation of multifunctional mesoporous SiO 2 nanoparticles and anti-tumor action . Nanotechnology 34:5, pages 055101.
Crossref
Qian Rui, Jun Gao, Zheng-Zhi Yin, Junyao Li, Wenrong Cai, Datong Wu & Yong Kong. (2023) A biodegradable pH and glutathione dual-triggered drug delivery system based on mesoporous silica, carboxymethyl chitosan and oxidized pullulan. International Journal of Biological Macromolecules 224, pages 1294-1302.
Crossref
Yi Liu, Man Zhu, Minsi Meng, Qiao Wang, Yun Wang, Yu Lei, Yanmin Zhang, Lin Weng & Xin Chen. (2023) A dual-responsive hyaluronic acid nanocomposite hydrogel drug delivery system for overcoming multiple drug resistance. Chinese Chemical Letters 34:1, pages 107583.
Crossref
Hareem Fatima, Shazia Shukrullah, Humaira Hussain, Hira Aslam & Muhammad Yasin Naz. 2023. Nanotechnology for Drug Delivery and Pharmaceuticals. Nanotechnology for Drug Delivery and Pharmaceuticals 235 258 .
Ana R. Neves, Swati Biswas, Ângela Sousa & Diana Costa. 2023. Advanced Nanoformulations. Advanced Nanoformulations 397 430 .
Saurabh Shah, Paras Famta, Deepkumar Bagasariya, Kondasingh Charankumar, Anupama Sikder, Rama Kashikar, Arun K. Kotha, Mahavir Bhupal Chougule, Dharmendra Kumar Khatri, Amit Asthana, Rajeev Singh Raghuvanshi, Shashi Bala Singh & Saurabh Srivastava. (2022) Tuning Mesoporous Silica Nanoparticles in Novel Avenues of Cancer Therapy. Molecular Pharmaceutics 19:12, pages 4428-4452.
Crossref
Elisabetta Mazzotta, Marzia De Santo, Domenico Lombardo, Antonella Leggio & Luigi Pasqua. (2022) Mesoporous silicas in materials engineering: Nanodevices for bionanotechnologies. Materials Today Bio 17, pages 100472.
Crossref
Vera Machado, Mariana Morais & Rui Medeiros. (2022) Hyaluronic Acid-Based Nanomaterials Applied to Cancer: Where Are We Now?. Pharmaceutics 14:10, pages 2092.
Crossref
Afreen Sultana, Mina Zare, Vinoy Thomas, T.S. Sampath Kumar & Seeram Ramakrishna. (2022) Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects. Medicine in Drug Discovery 15, pages 100134.
Crossref
Ipargul Hafiz, Zhezhe Li, Zhaozhi Wang, Hongji He, Xiaohui Tang & Mei Wang. (2022) Improving the antitumor efficiency against hepatocellular carcinoma by harmine-loaded liposomes with mitochondria targeting and legumain response. Journal of Drug Delivery Science and Technology 75, pages 103623.
Crossref
Fatemeh Ahmadi, Arezoo Sodagar-Taleghani, Pedram Ebrahimnejad, Seyyed Pouya Hadipour Moghaddam, Farzam Ebrahimnejad, Kofi Asare-Addo & Ali Nokhodchi. (2022) A review on the latest developments of mesoporous silica nanoparticles as a promising platform for diagnosis and treatment of cancer. International Journal of Pharmaceutics 625, pages 122099.
Crossref
Ying Li, Guoxing Deng, Xianlong Hu, Chenyang Li, Xiaodong Wang, Qinchang Zhu, Kai Zheng, Wei Xiong & Haiqiang Wu. (2022) Recent advances in mesoporous silica nanoparticle-based targeted drug-delivery systems for cancer therapy. Nanomedicine 17:18, pages 1253-1279.
Crossref
María Vallet-Regí, Ferdi Schüth, Daniel Lozano, Montserrat Colilla & Miguel Manzano. (2022) Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?. Chemical Society Reviews 51:13, pages 5365-5451.
Crossref
Kayalvizhi Rajendran, Akhilasree Karthikeyan & Uma Maheswari Krishnan. (2022) Emerging trends in nano-bioactive-mediated mitochondria-targeted therapeutic stratagems using polysaccharides, proteins and lipidic carriers. International Journal of Biological Macromolecules 208, pages 627-641.
Crossref
Qian Rui, Zheng‐Zhi Yin, Wenrong Cai, Junyao Li, Datong Wu & Yong Kong. (2022) Hyaluronic acid encapsulated aminated mesoporous silica nanoparticles for pH ‐responsive delivery of methotrexate and release kinetics . Bulletin of the Korean Chemical Society 43:5, pages 650-657.
Crossref
Han Yu, Na Ning, Xi Meng, Chuda Chittasupho, Lingling Jiang & Yunqi Zhao. (2022) Sequential Drug Delivery in Targeted Cancer Therapy. Pharmaceutics 14:3, pages 573.
Crossref
Zhengyang Yang, Wei Deng, Xiao Zhang, Yongbo An, Yishan Liu, Hongwei Yao & Zhongtao Zhang. (2022) Opportunities and Challenges of Nanoparticles in Digestive Tumours as Anti-Angiogenic Therapies. Frontiers in Oncology 11.
Crossref
Lin Ye, Qing Yao, Fengnan Xu, Liu He, Jieqiong Ding, Ruolei Xiao, Liqiong Ding & Binhua Luo. (2021) Preparation and antitumor activity of triphenylphosphine-based mitochondrial targeting polylactic acid nanoparticles loaded with 7-hydroxyl coumarin. Journal of Biomaterials Applications 36:6, pages 1064-1075.
Crossref
Rajesh Salve, Pramod Kumar, Kavita R. Gajbhiye, Rajnigandha A. Shende, Bhushan P. Chaudhari & Virendra Gajbhiye. 2022. Stimuli-Responsive Nanocarriers. Stimuli-Responsive Nanocarriers 237 264 .
Zi-ting Lin, Chun-hua Gong, Li Tang, Bi-lang Cao, Fan-sheng Kong, Zhong Wang & Yong-guang Bi. (2021) Study on preparation and in vitro anti-tumor activity of chitosan-modified mesoporous silica hybrids by GPTMS cross-linking agent. Reactive and Functional Polymers 169, pages 105072.
Crossref
Bijaideep Dutta, K.C. Barick & P.A. Hassan. (2021) Recent advances in active targeting of nanomaterials for anticancer drug delivery. Advances in Colloid and Interface Science 296, pages 102509.
Crossref
Kristina Živojević, Minja Mladenović, Mila Djisalov, Mirjana Mundzic, Eduardo Ruiz-Hernandez, Ivana Gadjanski & Nikola Ž. Knežević. (2021) Advanced mesoporous silica nanocarriers in cancer theranostics and gene editing applications. Journal of Controlled Release 337, pages 193-211.
Crossref
Sonia Iranpour, Ahmad Reza Bahrami, Amir Sh. Saljooghi & Maryam M. Matin. (2021) Application of smart nanoparticles as a potential platform for effective colorectal cancer therapy. Coordination Chemistry Reviews 442, pages 213949.
Crossref
Baranya Murugan, Suresh Sagadevan, Is Fatimah, Won-Chun Oh, Mohd Abd Motalib Hossain & Mohd Rafie Johan. (2021) Smart stimuli-responsive nanocarriers for the cancer therapy – nanomedicine. Nanotechnology Reviews 10:1, pages 933-953.
Crossref
Sepand Tehrani Fateh, Lida Moradi, Elmira Kohan, Michael R Hamblin & Amin Shiralizadeh Dezfuli. (2021) Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications. Beilstein Journal of Nanotechnology 12, pages 808-862.
Crossref
Shanshan Li, Long Zhang, Mingda Li, Jiao Huang, Baocheng Cui, Jie Jia, Zhaoming Guo, Kun Ma & Changhao Cui. (2021) Anti-CD19 mAb modified mesoporous titanium dioxide as exclusively targeting vector for efficient B-lymphoblastic leukemia therapy. Journal of Pharmaceutical Sciences 110:7, pages 2733-2742.
Crossref
Alsu R. Ibragimova, Dinar R. Gabdrakhmanov, Farida G. Valeeva, Leysan A. Vasileva, Anastasiia S. Sapunova, Alexandra D. Voloshina, Alina F. Saifina, Aidar T. Gubaidullin, Maxim P. Danilaev, Svetlana R. Egorova, Anna A. Tyryshkina, Alexander A. Lamberov, Ayrat R. Khamatgalimov, Gusel V. Sibgatullina, Dmitry V. Samigullin, Konstantin A. Petrov, Lucia Ya. Zakharova & Oleg G. Sinyashin. (2021) Mitochondria-targeted mesoporous silica nanoparticles noncovalently modified with triphenylphosphonium cation: Physicochemical characteristics, cytotoxicity and intracellular uptake. International Journal of Pharmaceutics 604, pages 120776.
Crossref
Devendra Choudhary, Hanmant Goykar, Tukaram Karanwad, Suraj Kannaujia, Vedant Gadekar & Manju Misra. (2021) An understanding of mitochondria and its role in targeting nanocarriers for diagnosis and treatment of cancer. Asian Journal of Pharmaceutical Sciences 16:4, pages 397-418.
Crossref
Rajesh Salve, Pramod Kumar, Worapol Ngamcherdtrakul, Virendra Gajbhiye & Wassana Yantasee. (2021) Stimuli-responsive mesoporous silica nanoparticles: A custom-tailored next generation approach in cargo delivery. Materials Science and Engineering: C 124, pages 112084.
Crossref
Milad Abbasi, Salar Hafez Ghoran, Mohammad Hadi Niakan, Kazem Jamali, Zohre Moeini, Ali Jangjou, Peyman Izadpanah & Ali Mohammad Amani. (2021) Mesoporous silica nanoparticle: Heralding a brighter future in cancer nanomedicine. Microporous and Mesoporous Materials 319, pages 110967.
Crossref
Arezoo Sodagar Taleghani, Ali Taghvaie Nakhjiri, Mohammad Javad Khakzad, Seyed Mahdi Rezayat, Pedram Ebrahimnejad, Amir Heydarinasab, Azim Akbarzadeh & Azam Marjani. (2021) Mesoporous silica nanoparticles as a versatile nanocarrier for cancer treatment: A review. Journal of Molecular Liquids 328, pages 115417.
Crossref
Wenlong LiWeiwei ZhangWeihao JinLongbao ZhuWanzhen LiPing SongYugui Tao & Fei Ge. (2021) Fabrication of a pH-Responsive 5-FU@MSN-SA Nanoplatform for Anti-Tumor Activity. Nano 16:03, pages 2150035.
Crossref
Si Si Liew, Xiaofei Qin, Jia Zhou, Lin Li, Wei Huang & Shao Q. Yao. (2020) Smart Design of Nanomaterials for Mitochondria‐Targeted Nanotherapeutics. Angewandte Chemie International Edition 60:5, pages 2232-2256.
Crossref
Si Si Liew, Xiaofei Qin, Jia Zhou, Lin Li, Wei Huang & Shao Q. Yao. (2020) Intelligentes Design von Nanomaterialien für Mitochondrien‐gerichtete Nanotherapeutika. Angewandte Chemie 133:5, pages 2260-2286.
Crossref
Eleen Dayana Mohamed Isa, Haslina Ahmad, Mohd Basyaruddin Abdul Rahman & Martin R. Gill. (2021) Progress in Mesoporous Silica Nanoparticles as Drug Delivery Agents for Cancer Treatment. Pharmaceutics 13:2, pages 152.
Crossref
Somayeh Handali, Mohsen Rezaei & Jalal Pourahmad. 2021. Mitochondrial Metabolism. Mitochondrial Metabolism 165 178 .
Punamjyoti Das & Malay K. Das. 2021. Multifunctional Theranostic Nanomedicines in Cancer. Multifunctional Theranostic Nanomedicines in Cancer 1 24 .
Mingyu Wang, Li Zhang, Yanfei Cai, Yang Yang, Lipeng Qiu, Yiting Shen, Jian Jin, Juan Zhou & Jinghua Chen. (2020) Bioengineered Human Serum Albumin Fusion Protein as Target/Enzyme/pH Three-Stage Propulsive Drug Vehicle for Tumor Therapy. ACS Nano 14:12, pages 17405-17418.
Crossref
Miguel Gisbert-Garzarán, Daniel Lozano & María Vallet-Regí. (2020) Mesoporous Silica Nanoparticles for Targeting Subcellular Organelles. International Journal of Molecular Sciences 21:24, pages 9696.
Crossref
Reju George Thomas, Suchithra Poilil Surendran & Yong Yeon Jeong. (2020) Tumor Microenvironment-Stimuli Responsive Nanoparticles for Anticancer Therapy. Frontiers in Molecular Biosciences 7.
Crossref
Li Chen, Guanya Chen, Zebin Yang, Hao Wang, Ning Liu, Yuxuan Liu, Kaiyi Fang, Yuguo Song & Xingang Guan. (2020) Enhanced cancer treatment by an acid-sensitive cytotoxic peptide-doxorubicin conjugate. Journal of Drug Delivery Science and Technology 60, pages 102048.
Crossref
Yimin Zhou, Qingni Xu, Chaohua Li, Yuqi Chen, Yueli Zhang & Bo Lu. (2020) Hollow mesoporous silica nanoparticles as nanocarriers employed in cancer therapy: A review. Frontiers of Materials Science 14:4, pages 373-386.
Crossref
Lanfeng Dong, Vinod Gopalan, Olivia Holland & Jiri Neuzil. (2020) Mitocans Revisited: Mitochondrial Targeting as Efficient Anti-Cancer Therapy. International Journal of Molecular Sciences 21:21, pages 7941.
Crossref
Baranya Murugan, Suresh Sagadevan, Anita Lett J, Is Fatimah, Kamrun Nahar Fatema, Won-Chun Oh, Faruq Mohammad & Mohd Rafie Johan. (2020) Role of mesoporous silica nanoparticles for the drug delivery applications. Materials Research Express 7:10, pages 102002.
Crossref
Fei Tong, Yicheng Ye, Bin Chen, Junbin Gao, Lu Liu, Juanfeng Ou, Jan C. M. van Hest, Shuwen Liu, Fei Peng & Yingfeng Tu. (2020) Bone-Targeting Prodrug Mesoporous Silica-Based Nanoreactor with Reactive Oxygen Species Burst for Enhanced Chemotherapy. ACS Applied Materials & Interfaces 12:31, pages 34630-34642.
Crossref
Jae Hyun Lim, Hyung Woo Choi, Sung Joon Mo & Bong Geun Chung. (2020) Dual-stimuli responsive mesoporous copper (II) sulfide nanocomposite for chemo-photothermal synergistic therapy. Microporous and Mesoporous Materials 302, pages 110228.
Crossref
Yasmine Alyassin, Elshaimaa G. Sayed, Prina Mehta, Ketan Ruparelia, Muhammad S. Arshad, Manoochehr Rasekh, Jennifer Shepherd, Israfil Kucuk, Philippe B. Wilson, Neenu Singh, Ming-Wei Chang, Dimitrios G. Fatouros & Zeeshan Ahmad. (2020) Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents. Drug Discovery Today 25:8, pages 1513-1520.
Crossref
Amirala Bakhshian Nik, Hossein Zare, Seyedsahameddin Razavi, Hesameddin Mohammadi, Pooya Torab Ahmadi, Narges Yazdani, Mehrdad Bayandori, Navid Rabiee & Jalal Izadi Mobarakeh. (2020) Smart drug delivery: Capping strategies for mesoporous silica nanoparticles. Microporous and Mesoporous Materials 299, pages 110115.
Crossref
Ghada G. Abdo, Moustafa M. Zagho & Ashraf Khalil. (2020) Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles. Emergent Materials 3:3, pages 407-425.
Crossref
Miguel Gisbert-Garzarán & María Vallet-Regí. (2020) Influence of the Surface Functionalization on the Fate and Performance of Mesoporous Silica Nanoparticles. Nanomaterials 10:5, pages 916.
Crossref
Rafael R. Castillo, Daniel Lozano & María Vallet-Regí. (2020) Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules. Pharmaceutics 12:5, pages 432.
Crossref
Shreffler, Pullan, Dailey, Mallik & Brooks. (2019) Overcoming Hurdles in Nanoparticle Clinical Translation: The Influence of Experimental Design and Surface Modification. International Journal of Molecular Sciences 20:23, pages 6056.
Crossref
Huanan Li, Qianyan Li, Wei Hou, Jingni Zhang, Chenhao Yu, Deping Zeng, Gang Liu & Faqi Li. (2019) Enzyme-Catalytic Self-Triggered Release of Drugs from a Nanosystem for Efficient Delivery to Nuclei of Tumor Cells. ACS Applied Materials & Interfaces 11:46, pages 43581-43587.
Crossref
Allaura S. Cone, Sara B. York & David G. MeckesJr.Jr.. (2019) Extracellular Vesicles in Epstein-Barr Virus Pathogenesis. Current Clinical Microbiology Reports 6:3, pages 121-131.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.