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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

Dimeric c(RGD) peptide conjugated nanostructured lipid carriers for efficient delivery of Gambogic acid to breast cancer

Dereje Kebebe1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;3 Department of Pharmaceutics, School of Pharmacy, Institute of Health Sciences, Jimma University, Jimma, Ethiopia
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Yumei Wu1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Bing Zhang1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Jian Yang1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Yuanyuan Liu1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Xinyue Li1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Zhe Ma1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Peng Lu1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Zhidong Liu1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Jiawei Li1 Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China;2 Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine , Tianjin301617, People’s Republic of China
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Pages 6179-6195 | Published online: 02 Aug 2019

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Wenli Dang, Bin Xing, Xintao Jia, Ying Zhang, Bei Jia, Changxiang Yu, Jiachen He, Ziwei Li, Huihui Li & Zhidong Liu. (2023) Subcellular Organelle-Targeted Nanostructured Lipid Carriers for the Treatment of Metastatic Breast Cancer. International Journal of Nanomedicine 18, pages 3047-3068.
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Lili Ren, Junfang Nie, Jie Wei, Yaning Li, Jun Yin, Xiaolong Yang & Guoguang Chen. (2021) RGD-targeted redox responsive nano micelle: co-loading docetaxel and indocyanine green to treat the tumor. Drug Delivery 28:1, pages 2024-2032.
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Mayur Aalhate, Srushti Mahajan, Hoshiyar Singh, Santosh Kumar Guru & Pankaj Kumar Singh. (2023) Nanomedicine in therapeutic warfront against estrogen receptor–positive breast cancer. Drug Delivery and Translational Research 13:6, pages 1621-1653.
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Pablo Graván, Aixa Aguilera-Garrido, Juan Antonio Marchal, Saúl A. Navarro-Marchal & Francisco Galisteo-González. (2023) Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment. Advances in Colloid and Interface Science 314, pages 102871.
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Yoseph Seo, Hayeon Lim, Hyunjun Park, Jiyun Yu, Jeongyun An, Hah Young Yoo & Taek Lee. (2023) Recent Progress of Lipid Nanoparticles-Based Lipophilic Drug Delivery: Focus on Surface Modifications. Pharmaceutics 15:3, pages 772.
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Ujala Gupta, Brojendra Nath Saren, Kedar Khaparkhuntikar, Jitender Madan & Pankaj Kumar Singh. (2022) Applications of lipid-engineered nanoplatforms in the delivery of various cancer therapeutics to surmount breast cancer. Journal of Controlled Release 348, pages 1089-1115.
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Shilpa Rana, Archana Bhatnagar, Suman Singh & Nirmal Prabhakar. (2022) Evaluation of liver specific ionizable lipid nanocarrier in the delivery of siRNA. Chemistry and Physics of Lipids 246, pages 105207.
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Liang Wang, Shixia Zhu, Chunpeng Zou, Hongju Kou, Maosheng Xu & Jie Li. (2022) Preparation and evaluation of the anti-cancer properties of RGD-modified curcumin-loaded chitosan/perfluorohexane nanocapsules in vitro. Heliyon 8:7, pages e09931.
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Aiswarya Chaudhuri, Dulla Naveen Kumar, Deepa Dehari, Sanjay Singh, Pradeep Kumar, Pradeep Kumar Bolla, Dinesh Kumar & Ashish Kumar Agrawal. (2022) Emergence of Nanotechnology as a Powerful Cavalry against Triple-Negative Breast Cancer (TNBC). Pharmaceuticals 15:5, pages 542.
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Daohe Wei, Han Yang, Yue Zhang, Xinhui Zhang, Jian Wang, Xiaoli Wu & Jin Chang. (2022) Nano-traditional Chinese medicine: a promising strategy and its recent advances. Journal of Materials Chemistry B 10:16, pages 2973-2994.
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Wenli Dang, Pan Guo, Xunan Song, Ying Zhang, Nan Li, Changxiang Yu, Bin Xing, Rui Liu, Xintao Jia, Qingqing Zhang, Xiaojiao Feng & Zhidong Liu. (2022) Nuclear Targeted Peptide Combined With Gambogic Acid for Synergistic Treatment of Breast Cancer. Frontiers in Chemistry 9.
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Kammila Martins Nicolau Costa, Camila Beatriz Barros Araújo, Ana Lígia Santiago Barros, Mariana Rillo Sato & João Augusto Oshiro-Júnior. 2022.
Ali Sartaj, Sanjula Baboota & Javed Ali. (2021) Exploring the therapeutic potential of nanostructured lipid carrier approaches to tackling the inherent lacuna of chemotherapeutics and herbal drugs against breast cancer. Journal of Drug Delivery Science and Technology 63, pages 102451.
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Liying Wang, Xiangbo Wang, Lina Shen, Majed Alrobaian, Sunil K. Panda, Hussain A. Almasmoum, Mazen M. Ghaith, Riyad A. Almaimani, Ibrahim Abdel Aziz Ibrahim, Tanuja Singh, Abdullah A. Baothman, Hani Choudhry & Sarwar Beg. (2021) Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma multiforme. Biomedicine & Pharmacotherapy 138, pages 111461.
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Meng Wang, Hao Li, Biao Huang, Song Chen, Ran Cui, Zhi‐Jun Sun, Mingxi Zhang & Taolei Sun. (2021) An Ultra‐Stable, Oxygen‐Supply Nanoprobe Emitting in Near‐Infrared‐II Window to Guide and Enhance Radiotherapy by Promoting Anti‐Tumor Immunity. Advanced Healthcare Materials 10:12, pages 2100090.
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Zhe Ma, Jiaxin Pi, Ying Zhang, Huan Qin, Bing Zhang, Nan Li, Zheng Li & Zhidong Liu. (2021) Enhanced Anticancer Efficacy of Dual Drug-Loaded Self-Assembled Nanostructured Lipid Carriers Mediated by pH-Responsive Folic Acid and Human-Derived Cell Penetrating Peptide dNP2. Pharmaceutics 13:5, pages 600.
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Zhe Ma, Nan Li, Bing Zhang, YuYu Hui, Ying Zhang, Peng Lu, Jiaxin Pi & Zhidong Liu. (2020) Dual drug-loaded nano-platform for targeted cancer therapy: toward clinical therapeutic efficacy of multifunctionality. Journal of Nanobiotechnology 18:1.
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Elham Hatami, Meena Jaggi, Subhash C. Chauhan & Murali M. Yallapu. (2020) Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1874:1, pages 188381.
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Kuldeep Rajpoot. (2020) Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications. Current Cancer Drug Targets 20:4, pages 271-287.
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