381
Views
66
CrossRef citations to date
0
Altmetric
Original Research

Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis

, , &
Pages 5187-5199 | Published online: 12 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Martin Hoenigl, Rosanne Sprute, Amir Arastehfar, John R. Perfect, Cornelia Lass-Flörl, Romuald Bellmann, Juergen Prattes, George R. Thompson$suffix/text()$suffix/text(), Nathan P. Wiederhold, Mohanad M. Al Obaidi, Birgit Willinger, Maiken C. Arendrup, Philipp Koehler, Matteo Oliverio, Matthias Egger, Ilan S. Schwartz, Oliver A. Cornely, Peter G. Pappas & Robert Krause. (2022) Invasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action. Expert Opinion on Investigational Drugs 31:8, pages 795-812.
Read now
Daniele R. Giacobbe, Laura Magnasco, Chiara Sepulcri, Malgorzata Mikulska, Philipp Koehler, Oliver A. Cornely & Matteo Bassetti. (2021) Recent advances and future perspectives in the pharmacological treatment of Candida auris infections. Expert Review of Clinical Pharmacology 14:10, pages 1205-1220.
Read now

Articles from other publishers (64)

Edward Otieno, Yun Huang, Na Li, Tong Li, Mingyu Wang, Xiaoyan Qiu & Xiong Xiao. (2023) Utilization of superparamagnetic iron oxide nanoparticles (SPIONs) as a vector for drug delivery. Applied Nanoscience.
Crossref
Gabriella Maria Andriani, Lais Fernanda de Almeida Spoladori, Marciéli Fabris, Priscila Goes Camargo, Patrícia Morais Lopes Pereira, Jussevania Pereira Santos, Guilherme Bartolomeu-Gonçalves, Lais Alonso, Cesar Armando Contreras Lancheros, Antonio Alonso, Celso Vataru Nakamura, Fernando MacedoJr.Jr., Phileno Pinge-Filho, Lucy Megumi Yamauchi, Marcelle de Lima Ferreira Bispo, Eliandro Reis Tavares & Sueli Fumie Yamada-Ogatta. (2023) Synergistic antifungal interaction of N-(butylcarbamothioyl) benzamide and amphotericin B against Cryptococcus neoformans. Frontiers in Microbiology 14.
Crossref
Julia Sapienza Passos, Vanessa F.M.C. Dartora, Giovanna Cassone Salata, Isabella Draszesski Malagó & Luciana B. Lopes. (2023) Contributions of nanotechnology to the intraductal drug delivery for local treatment and prevention of breast cancer. International Journal of Pharmaceutics 635, pages 122681.
Crossref
Eric Alvares, Stanley Tantoro, Christian Julius Wijaya, Kuan-Chen Cheng, Felycia Edi Soetaredjo, Hsien-Yi Hsu, Artik Elisa Angkawijaya, Alchris Woo Go, Chang-Wei Hsieh & Shella Permatasari Santoso. (2023) Preparation of MIL100/MIL101-alginate composite beads for selective phosphate removal from aqueous solution. International Journal of Biological Macromolecules 231, pages 123322.
Crossref
Daniel Felipe Freitas De Jesus, Aline Luiza Duarte De Freitas, Isadora Maria De Oliveira, Larissa Costa De Almeida, Rafael Wesley Bastos, Cristina de Castro Spadari, Analy Sales de Azevedo Melo, Daniel de Assis Santos, Letícia Veras Costa-Lotufo, Flavia C. G. Reis, Marcio L. Rodrigues, Hélio Alexandre Stefani & Kelly Ishida. (2023) Organoselenium Has a Potent Fungicidal Effect on Cryptococcus neoformans and Inhibits the Virulence Factors. Antimicrobial Agents and Chemotherapy.
Crossref
Nika Kučuk, Mateja Primožič, Željko Knez & Maja Leitgeb. (2023) Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications. International Journal of Molecular Sciences 24:4, pages 3188.
Crossref
Parisa Dehghani, Monireh Esmaeili Rad, Atefeh Zarepour, Ponnurengam Malliappan Sivakumar & Ali Zarrabi. (2023) An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment. Mini-Reviews in Medicinal Chemistry 23:2, pages 192-216.
Crossref
Eswhari Ganasan, Hanis Mohd Yusoff, Alyza Azzura Azmi, Poh Wai Chia, Su Shiung Lam, Su-Yin Kan, Rock Keey Liew, Katta Venkateswarlu & Chook Kiong Teo. (2022) Food additives for the synthesis of metal nanoparticles: a review. Environmental Chemistry Letters 21:1, pages 525-538.
Crossref
Nataly Paredes da Rocha, Aline de Souza, Megumi Nishitani Yukuyama, Thayna Lopes Barreto, Luiza de O. Macedo, Raimar Löbenberg, Gabriel Lima Barros de Araújo, Kelly Ishida & Nádia Araci Bou-Chacra. (2023) Highly water-soluble dapsone nanocrystals: Towards innovative preparations for an undermined drug. International Journal of Pharmaceutics 630, pages 122428.
Crossref
Ruth Zomuansangi, Bhim Pratap Singh, Garima Singh, Zothanpuia, Prashant Kumar Singh, Jae Jun Song, Arun S. Kharat, Purbhajyoti Deka & Mukesh Kumar Yadav. 2023. Nanotechnology and Human Health. Nanotechnology and Human Health 381 404 .
Sara H. Helal, Heba M. M. Abdel-Aziz, Mustafa M. El-Zayat & Mohammed N. A. Hasaneen. (2022) Preparation, characterization and properties of three different nanomaterials either alone or loaded with nystatin or fluconazole antifungals. Scientific Reports 12:1.
Crossref
José Izo Santana da Silva de Jesus, Felipe Rebello Lourenço, Kelly Ishida, Thayná Lopes Barreto, Valdir Carlos Avino, Edson dos Santos Neto & Nádia Araci Bou-Chacra. (2022) Besifloxacin Nanocrystal: Towards an Innovative Ophthalmic Preparation. Pharmaceutics 14:10, pages 2221.
Crossref
Ali Jangjou, Zahra Zareshahrabadi, Milad Abbasi, Amirreza Talaiekhozani, Hesam Kamyab, Shreeshivadasan Chelliapan, Ahmad Vaez, Ali Golchin, Lobat Tayebi, Ehsan Vafa, Ali Mohammad Amani & Hossein Faramarzi. (2022) Time to Conquer Fungal Infectious Diseases: Employing Nanoparticles as Powerful and Versatile Antifungal Nanosystems against a Wide Variety of Fungal Species. Sustainability 14:19, pages 12942.
Crossref
Giovanna C. Salata, Isabella D. Malagó & Luciana B. Lopes. (2022) A Lipid-Based In Situ-Forming Hexagonal Phase for Prolonged Retention and Drug Release in the Breast Tissue. AAPS PharmSciTech 23:7.
Crossref
Mohammad A. S. Abourehab, Rahul R. Rajendran, Anshul Singh, Sheersha Pramanik, Prachi Shrivastav, Mohammad Javed Ansari, Ravi Manne, Larissa Souza Amaral & A. Deepak. (2022) Alginate as a Promising Biopolymer in Drug Delivery and Wound Healing: A Review of the State-of-the-Art. International Journal of Molecular Sciences 23:16, pages 9035.
Crossref
Cristina de Castro Spadari, Thayná Lopes Barreto, Vagner Tebaldi de Queiroz, Walysson Ferreira de Paiva, Sergio Antonio Fernandes, Ângelo de Fátima & Kelly Ishida. (2022) Ketoconazole/calix[n]arenes-based compounds improve the antifungal activity against azole-resistant Candida isolates. Journal of Medical Mycology 32:2, pages 101254.
Crossref
Lais Alonso, Laryssa Ketelyn Lima Pimenta, André Kipnis & Antonio Alonso. (2022) Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol. Biochimica et Biophysica Acta (BBA) - Biomembranes 1864:5, pages 183872.
Crossref
Giovanna C. Salata, Alexsandra C. Apolinário, Julia S. Passos & Luciana B. Lopes. (2022) Use of Lipid Nanoparticles, Nanoemulsions, and Vesicles for Topical Delivery of Active Compounds Employed in the Cosmetic Field. Current Cosmetic Science 1:1.
Crossref
Gisoo Maleki, Ernst J. Woltering & M.R. Mozafari. (2022) Applications of chitosan-based carrier as an encapsulating agent in food industry. Trends in Food Science & Technology 120, pages 88-99.
Crossref
Barbara Malheiros, Raphael Dias de Castro, Mayra C. Lotierzo, Bruna R. Casadei, Paolo Mariani & Leandro R.S. Barbosa. (2022) Influence of hexadecylphosphocholine (Miltefosine) in phytantriol-based cubosomes: A structural investigation. Colloids and Surfaces A: Physicochemical and Engineering Aspects 632, pages 127720.
Crossref
Fereshteh Bayat, Fatemeh Mehryab, Sarah Akhlaghi & Azadeh Haeri. 2022. Emerging Nanomaterials and Nano-Based Drug Delivery Approaches to Combat Antimicrobial Resistance. Emerging Nanomaterials and Nano-Based Drug Delivery Approaches to Combat Antimicrobial Resistance 179 232 .
Samuel Rodrigues dos Santos Junior, Andre Correa Amaral & Carlos Pelleschi Taborda. 2022. Nanotechnology for Infectious Diseases. Nanotechnology for Infectious Diseases 151 173 .
Ifeanyi Elibe Mba & Emeka Innocent Nweze. 2022. Nanotechnology for Infectious Diseases. Nanotechnology for Infectious Diseases 25 51 .
Victória Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama & Angela Faustino Jozala. (2021) Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity. Scientific Reports 11:1.
Crossref
Mei-nian Xu, Li Li, Wen Pan, Huan-xin Zheng, Meng-lei Wang, Xiao-ming Peng, Si-qi Dai, Ying-mei Tang, Kang Zeng & Xiao-wen Huang. (2021) Zinc Oxide Nanoparticles Prime a Protective Immune Response in Galleria mellonella to Defend Against Candida albicans. Frontiers in Microbiology 12.
Crossref
Humzah Jamshaid, Fakhar ud Din & Gul Majid Khan. (2021) Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight. Journal of Nanobiotechnology 19:1.
Crossref
Ankur Sood, Aastha Gupta & Garima Agrawal. (2021) Recent advances in polysaccharides based biomaterials for drug delivery and tissue engineering applications. Carbohydrate Polymer Technologies and Applications 2, pages 100067.
Crossref
Eryka Oliveira de Andrades, João Marcos Antônio Rodrigues da Costa, Francisco Edmar Moreira de Lima Neto, Alyne Rodrigues de Araujo, Fabio de Oliveira Silva Ribeiro, Andreanne Gomes Vasconcelos, Antônia Carla de Jesus Oliveira, José Lamartine Soares Sobrinho, Miguel Peixoto de Almeida, Ana P. Carvalho, Jhones Nascimento Dias, Ingrid Gracielle Martins Silva, Patrícia Albuquerque, Ildinete Silva Pereira, Doralina do Amaral Rabello, Adriany das Graças Nascimento Amorim, José Roberto de Souza de Almeida Leite & Durcilene Alves da Silva. (2021) Acetylated cashew gum and fucan for incorporation of lycopene rich extract from red guava (Psidium guajava L.) in nanostructured systems: Antioxidant and antitumor capacity. International Journal of Biological Macromolecules 191, pages 1026-1037.
Crossref
Andrea Dodero, Stefano Alberti, Giulia Gaggero, Maurizio Ferretti, Rodolfo Botter, Silvia Vicini & Maila Castellano. (2021) An Up‐to‐Date Review on Alginate Nanoparticles and Nanofibers for Biomedical and Pharmaceutical Applications. Advanced Materials Interfaces 8:22, pages 2100809.
Crossref
Gaby Scheunemann, Bruna N. Fortes, Nilton Lincopan & Kelly Ishida. (2021) Caspofungin Inhibits Mixed Biofilms of Candida albicans and Methicillin-Resistant Staphylococcus aureus and Displays Effectiveness in Coinfected Galleria mellonella Larvae. Microbiology Spectrum 9:2.
Crossref
Miguel Hueso, Adrián Mallén, Marc Suñé-Pou, Josep M. Aran, Josep M. Suñé-Negre & Estanislao Navarro. (2021) ncRNAs in Therapeutics: Challenges and Limitations in Nucleic Acid-Based Drug Delivery. International Journal of Molecular Sciences 22:21, pages 11596.
Crossref
Thayná L Barreto, Luciana B Lopes, Analy SA Melo & Kelly Ishida. (2021) In vivo synergism of free miltefosine or in alginate-based nanocarrier combined with voriconazole on aspergillosis . Future Microbiology 16:15, pages 1153-1160.
Crossref
Pariya Rahnemoon, Mahboobe Sarabi-Jamab, Aram Bostan & Elaheh Mansouri. (2021) Nano-encapsulation of pomegranate (Punica granatum L.) peel extract and evaluation of its antimicrobial properties on coated chicken meat. Food Bioscience 43, pages 101331.
Crossref
Giovanna Cassone Salata, Isabella D. Malagó, Vanessa F. M. Carvalho Dartora, Ana Flávia Marçal Pessoa, Márcia Carvalho de Abreu Fantini, Soraia K. P. Costa, João Agostinho Machado-Neto & Luciana B. Lopes. (2021) Microemulsion for Prolonged Release of Fenretinide in the Mammary Tissue and Prevention of Breast Cancer Development. Molecular Pharmaceutics 18:9, pages 3401-3417.
Crossref
Chanez Bennacef, Sylvie Desobry-Banon, Laurent Probst & Stéphane Desobry. (2021) Advances on alginate use for spherification to encapsulate biomolecules. Food Hydrocolloids 118, pages 106782.
Crossref
Pragya Prasanna, Prakash Kumar, Saurabh Kumar, Vinod Kumar Rajana, Vishnu Kant, Surendra Rajit Prasad, Utpal Mohan, V. Ravichandiran & Debabrata Mandal. (2021) Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis – A review. Biomedicine & Pharmacotherapy 141, pages 111920.
Crossref
Thaila Fernanda dos Reis, Maria Augusta Crivelente Horta, Ana Cristina Colabardini, Caroline Mota Fernandes, Lilian Pereira Silva, Rafael Wesley Bastos, Maria Vitória de Lazari Fonseca, Fang Wang, Celso Martins, Márcio L. Rodrigues, Cristina Silva Pereira, Maurizio Del Poeta, Koon Ho Wong & Gustavo H. Goldman. (2021) Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine. mBio 12:4.
Crossref
Lais Alonso, Sebastião Antônio Mendanha, Rodrigo Saar Gomes, Miriam Leandro Dorta & Antonio Alonso. (2021) Comparative EPR spectroscopy analysis of amphotericin B and miltefosine interactions with Leishmania, erythrocyte and macrophage membranes. European Journal of Pharmaceutical Sciences 163, pages 105859.
Crossref
Rodrigo Rollin-Pinheiro, Yuri de Castro Almeida, Victor Pereira Rochetti, Mariana Ingrid Dutra da Silva Xisto, Luana Pereira Borba-Santos, Sonia Rozental & Eliana Barreto-Bergter. (2021) Miltefosine Against Scedosporium and Lomentospora Species: Antifungal Activity and Its Effects on Fungal Cells. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Sandra Costa-Fernandez, Jenyffer K.R. Matos, Gaby S. Scheunemann, Giovanna C. Salata, Marlus Chorilli, Il-Sei Watanabe, Gabriel L.B. de Araujo, Marinilce F. Santos, Kelly Ishida & Luciana B. Lopes. (2021) Nanostructured lipid carriers containing chitosan or sodium alginate for co-encapsulation of antioxidants and an antimicrobial agent for potential application in wound healing. International Journal of Biological Macromolecules 183, pages 668-680.
Crossref
Rebecca Marie Dewhurst, Elisa Molinari & John A. Sayer. (2021) Cell preservation methods and its application to studying rare disease. Molecular and Cellular Probes 56, pages 101694.
Crossref
Luana Rossato, Marielle Camargo dos Santos, Roxana G. Vitale, Sybren Hoog & Kelly Ishida. (2020) Alternative treatment of fungal infections: Synergy with non‐antifungal agents. Mycoses 64:3, pages 232-244.
Crossref
Asmaa S. El-Houssiny, Ehab A. Fouad & Ahmed G. Hegazi. (2021) A Comparative Antimicrobial Activity Study of Moringa oleifera Extracts Encapsulated within ALg Nanoparticles. Nanoscience & Nanotechnology-Asia 11:1, pages 144-152.
Crossref
E. Abd, J. Gomes, C. C. Sales, S. Yousef, F. Forouz, K. C. Telaprolu, M. S. Roberts, J. E. Grice, P. S. Lopes, V. R. Leite‐Silva & N. Andréo‐Filho. (2020) Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test. International Journal of Cosmetic Science 43:1, pages 1-10.
Crossref
Kasula Nagaraja, Kummara Madhusudana Rao & Kummari S.V. Krishna Rao. 2021. Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine. Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine 357 393 .
Cristina de Castro Spadari, Taissa Vila, Vinícius de Morais Barroso & Kelly Ishida. 2021. Encyclopedia of Mycology. Encyclopedia of Mycology 456 467 .
Luis M. Z. Argomedo, Vinicius M. Barroso, Cristiane S. Barreiro, Mariana P. Darbem, Kelly Ishida & Hélio A. Stefani. (2020) Novel 2-Aryloxazoline Compounds Exhibit an Inhibitory Effect on Candida spp., Including Antifungal-Resistant Isolates . ACS Medicinal Chemistry Letters 11:12, pages 2470-2475.
Crossref
Viviane Lopes Rocha Correa, Juliana Assis Martins, Tainara Ribeiro de Souza, Gabriel de Castro Nunes Rincon, Marina Pacheco Miguel, Liliana Borges de Menezes & Andre Correa Amaral. (2020) Melatonin loaded lecithin-chitosan nanoparticles improved the wound healing in diabetic rats. International Journal of Biological Macromolecules 162, pages 1465-1475.
Crossref
Ifeanyi Elibe Mba & Emeka Innocent Nweze. (2020) The use of nanoparticles as alternative therapeutic agents against Candida infections: an up-to-date overview and future perspectives. World Journal of Microbiology and Biotechnology 36:11.
Crossref
Hazem Choukaife, Abd Almonem Doolaanea & Mulham Alfatama. (2020) Alginate Nanoformulation: Influence of Process and Selected Variables. Pharmaceuticals 13:11, pages 335.
Crossref
Brenda Kischkel, Suélen A. Rossi, Samuel R. SantosJuniorJunior, Joshua D. Nosanchuk, Luiz R. Travassos & Carlos P. Taborda. (2020) Therapies and Vaccines Based on Nanoparticles for the Treatment of Systemic Fungal Infections. Frontiers in Cellular and Infection Microbiology 10.
Crossref
Rony Lucas Silva Viana, Gabriel Pereira Fidelis, Mayara Jane Campos Medeiros, Marcelo Antonio Morgano, Monique Gabriela Chagas Faustino Alves, Luiz Felipe Domingues Passero, Daniel Lima Pontes, Raquel Cordeiro Theodoro, Thales Domingos Arantes, Diego Araujo Sabry, Guilherme Lanzi Sassaki, Raniere Fagundes Melo-Silveira & Hugo Alexandre Oliveira Rocha. (2020) Green Synthesis of Antileishmanial and Antifungal Silver Nanoparticles Using Corn Cob Xylan as a Reducing and Stabilizing Agent. Biomolecules 10:9, pages 1235.
Crossref
Dewi Melani Hariyadi & Nazrul Islam. (2020) Current Status of Alginate in Drug Delivery. Advances in Pharmacological and Pharmaceutical Sciences 2020, pages 1-16.
Crossref
Merlis P. Alvarez-Berrios, Lisa M. Aponte-Reyes, Lourdes Diaz-Figueroa, Juan Vivero-Escoto, Alexis Johnston & David Sanchez-Rodriguez. (2020) Preparation and In Vitro Evaluation of Alginate Microparticles Containing Amphotericin B for the Treatment of Candida Infections . International Journal of Biomaterials 2020, pages 1-12.
Crossref
Thayná Lopes Barreto, Luana Rossato, Aline Luiza Duarte de Freitas, Jacques F. Meis, Luciana Biagini Lopes, Arnaldo Lopes Colombo & Kelly Ishida. (2020) Miltefosine as an alternative strategy in the treatment of the emerging fungus Candida auris. International Journal of Antimicrobial Agents 56:2, pages 106049.
Crossref
Julia Sapienza Passos, Luiza Capello de Martino, Vanessa Franco Carvalho Dartora, Gabriel L.B. de Araujo, Kelly Ishida & Luciana B. Lopes. (2020) Development, skin targeting and antifungal efficacy of topical lipid nanoparticles containing itraconazole. European Journal of Pharmaceutical Sciences 149, pages 105296.
Crossref
Yongqin Wu, Mengying Wu, Jing Gao & Chunmei Ying. (2020) Antifungal Activity and Mode of Action of Miltefosine Against Clinical Isolates of Candida krusei. Frontiers in Microbiology 11.
Crossref
Cristina de Castro Spadari, Fernanda Wirth, Luciana Biagini Lopes & Kelly Ishida. (2020) New Approaches for Cryptococcosis Treatment. Microorganisms 8:4, pages 613.
Crossref
Rubaiya Jesmin & Anindya Chanda. (2020) Restricting mycotoxins without killing the producers: a new paradigm in nano-fungal interactions. Applied Microbiology and Biotechnology 104:7, pages 2803-2813.
Crossref
Sana Jemel, Jacques Guillot, Kalthoum Kallel, Françoise Botterel & Eric Dannaoui. (2020) Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review. Microorganisms 8:3, pages 390.
Crossref
Fernanda Walt Mendes da Silva de Bastiani, Cristina de Castro Spadari, Jenyffer Kelly Rocha de Matos, Giovanna Cassone Salata, Luciana Biagini Lopes & Kelly Ishida. (2020) Nanocarriers Provide Sustained Antifungal Activity for Amphotericin B and Miltefosine in the Topical Treatment of Murine Vaginal Candidiasis. Frontiers in Microbiology 10.
Crossref
Mahendra Rai & Alka Yadav. 2020. Nanotechnology in Skin, Soft Tissue, and Bone Infections. Nanotechnology in Skin, Soft Tissue, and Bone Infections 109 120 .
A G Hegazi, A S El-Houssiny & E A Fouad. (2019) Egyptian propolis 14: Potential antibacterial activity of propolis-encapsulated alginate nanoparticles against different pathogenic bacteria strains. Advances in Natural Sciences: Nanoscience and Nanotechnology 10:4, pages 045019.
Crossref
Wall, Herrera & Lopez-Ribot. (2019) Repositionable Compounds with Antifungal Activity against Multidrug Resistant Candida auris Identified in the Medicines for Malaria Venture’s Pathogen Box. Journal of Fungi 5:4, pages 92.
Crossref