Advanced search
Publication Cover
International Journal of Nanomedicine Volume 14, 2019 - Issue
Submit an article Journal homepage
1,099
Views
134
CrossRef citations to date
0
Altmetric
Original Research

A Nanodrug Consisting Of Doxorubicin And Exosome Derived From Mesenchymal Stem Cells For Osteosarcoma Treatment In Vitro

Hongxiang Wei1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
,
Jinyuan Chen2 Department of Centralab, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
,
Shenglin Wang1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
,
Feihuan Fu3 Department of Endocrinology, The County Hospital of Anxi, Anxi362400, People’s Republic of China
,
Xia Zhu1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
,
Chaoyang Wu1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
,
Zhoujie Liu4 Department of Pharmacy, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-3491-8859
ORCID Icon,
Guangxian Zhong1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Jianhua Lin1 Department of Orthopaedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou350004, People’s Republic of China
 show all
Pages 8603-8610 | Published online: 01 Nov 2019

Citations (134)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (12)

Zaijun Zou, Han Li, Gang Xu, Yunxiang Hu, Weiguo Zhang & Kang Tian. (2023) Current Knowledge and Future Perspectives of Exosomes as Nanocarriers in Diagnosis and Treatment of Diseases. International Journal of Nanomedicine 18, pages 4751-4778.
Read now
P. A. Flores de los Rios, R. G. Casañas Pimentel & E. San Martín Martínez. (2023) Nanodrugs against cancer: biological considerations in its redesign. International Journal of Polymeric Materials and Polymeric Biomaterials 72:17, pages 1340-1359.
Read now
Maryam Adelipour, David M. Lubman & Jeongkwon Kim. (2023) Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicine. Expert Opinion on Biological Therapy 23:6, pages 491-507.
Read now
Qixiang Feng, Yu Zhang, Yuelin Fang, Xinru Kong, Zhijing He, Jianbo Ji, Xiaoye Yang & Guangxi Zhai. (2023) Research progress of exosomes as drug carriers in cancer and inflammation. Journal of Drug Targeting 31:4, pages 335-353.
Read now
Jinkui Wang, Mujie Li, Liming Jin, Peng Guo, Zhaoxia Zhang, Chenghao Zhanghuang, Xiaojun Tan, Tao Mi, Jiayan Liu, Xin Wu, Guanghui Wei & Dawei He. (2022) Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo. Drug Delivery 29:1, pages 3291-3303.
Read now
Sasmita Samal, Pratigyan Dash & Mamoni Dash. (2021) Drug Delivery to the Bone Microenvironment Mediated by Exosomes: An Axiom or Enigma. International Journal of Nanomedicine 16, pages 3509-3540.
Read now
Feifei Pu, Fengxia Chen, Zhicai Zhang, Jianxiang Liu & Zengwu Shao. (2020) Information Transfer and Biological Significance of Neoplastic Exosomes in the Tumor Microenvironment of Osteosarcoma. OncoTargets and Therapy 13, pages 8931-8940.
Read now
Meilin Zhang, Ying Du, Shujun Wang & Baoan Chen. (2020) A Review of Biomimetic Nanoparticle Drug Delivery Systems Based on Cell Membranes. Drug Design, Development and Therapy 14, pages 5495-5503.
Read now
Rong Xu, Yingying Bai, Shudan Min, Xiaoxuan Xu, Tianyu Tang & Shenghong Ju. (2020) In vivo Monitoring and Assessment of Exogenous Mesenchymal Stem Cell-Derived Exosomes in Mice with Ischemic Stroke by Molecular Imaging. International Journal of Nanomedicine 15, pages 9011-9023.
Read now
Abhimanyu Thakur, Rakesh Kumar Sidu, Heng Zou, Md Kowsar Alam, Mengsu Yang & Youngjin Lee. (2020) Inhibition of Glioma Cells’ Proliferation by Doxorubicin-Loaded Exosomes via Microfluidics. International Journal of Nanomedicine 15, pages 8331-8343.
Read now
Ting Huyan, Hongduo Li, Hourong Peng, Jinzhao Chen, Ruixin Yang, Wei Zhang & Qi Li. (2020) Extracellular Vesicles – Advanced Nanocarriers in Cancer Therapy: Progress and Achievements. International Journal of Nanomedicine 15, pages 6485-6502.
Read now
Yoshihiko Kakiuchi, Shinji Kuroda, Nobuhiko Kanaya, Shunsuke Kagawa, Hiroshi Tazawa & Toshiyoshi Fujiwara. Exosomes as a drug delivery tool for cancer therapy: a new era for existing drugs and oncolytic viruses. Expert Opinion on Therapeutic Targets 0:0, pages 1-10.
Read now

Articles from other publishers (122)

Nazanin Amiryaghoubi, Marziyeh Fathi, Jaleh Barar, Hossein Omidian & Yadollah Omidi. (2023) Advanced nanoscale drug delivery systems for bone cancer therapy. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869:6, pages 166739.
Crossref
Disha N. Moholkar, Raghuram Kandimalla, Ramesh C. Gupta & Farrukh Aqil. (2023) Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes. Cancer Letters 565, pages 216220.
Crossref
Azim Ansari, Afzal Hussain, Raju Wadekar, Mohammad A. Altamimi, Abdul Malik, Md Ali Mujtaba, Mohammad Yousuf Ansari, Mohd Usman Mohd Siddique & Sameer N. Goyal. (2023) Nanovesicles based drug targeting to control tumor growth and metastasis. Advances in Cancer Biology - Metastasis 7, pages 100083.
Crossref
Chung-Sung Lee, Rajendra K. Singh, Hee Sook Hwang, Na-Hyun Lee, Amal George Kurian, Jung-Hwan Lee, Hye Sung Kim, Min Lee & Hae-Won Kim. (2023) Materials-based nanotherapeutics for injured and diseased bone. Progress in Materials Science 135, pages 101087.
Crossref
Ali Hazrati, Zahra Mirsanei, Neda Heidari, Kosar Malekpour, Nasim Rahmani-Kukia, Ardeshir Abbasi & Sara Soudi. (2023) The potential application of encapsulated exosomes: A new approach to increase exosomes therapeutic efficacy. Biomedicine & Pharmacotherapy 162, pages 114615.
Crossref
Tianjiao Geng, Euphemia Leung, Lawrence W. Chamley & Zimei Wu. (2023) Functionalisation of extracellular vesicles with cyclic-RGDyC potentially for glioblastoma targeted intracellular drug delivery. Biomaterials Advances 149, pages 213388.
Crossref
Natalia Todosenko, Igor Khlusov, Kristina Yurova, Olga Khaziakhmatova & Larisa Litvinova. (2023) Signal Pathways and microRNAs in Osteosarcoma Growth and the Dual Role of Mesenchymal Stem Cells in Oncogenesis. International Journal of Molecular Sciences 24:10, pages 8993.
Crossref
Xuemei Hu, Jing Zhang, Qi Xiang, Guoqiao Huang, Quan Yuan, Yuzhe Wang & Zhifa Shen. (2023) Study on Sgc8 aptamer-mediated nucleic acid nanomaterial-doxorubicin complex for tumor targeted therapy. European Journal of Pharmaceutics and Biopharmaceutics 186, pages 7-17.
Crossref
Margaret Wallen, Farrukh Aqil, Wendy Spencer & Ramesh C. Gupta. (2023) Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics. Cancer Letters 561, pages 216141.
Crossref
Amir Hossein Mohammadi, Zeinab Ghazvinian, Fatemeh Bagheri, Masako Harada & Kaveh Baghaei. (2023) Modification of Extracellular Vesicle Surfaces: An Approach for Targeted Drug Delivery. BioDrugs 37:3, pages 353-374.
Crossref
Cristiana Ulpiano, Cláudia L. da Silva & Gabriel A. Monteiro. (2023) Bioengineered Mesenchymal-Stromal-Cell-Derived Extracellular Vesicles as an Improved Drug Delivery System: Methods and Applications. Biomedicines 11:4, pages 1231.
Crossref
David J. Rademacher. (2023) Potential for Therapeutic-Loaded Exosomes to Ameliorate the Pathogenic Effects of α-Synuclein in Parkinson’s Disease. Biomedicines 11:4, pages 1187.
Crossref
Gayatri Patel, Tejas Girish Agnihotri, Manoj Gitte, Tanuja Shinde, Shyam Sudhakar Gomte, Roshan Goswami & Aakanchha Jain. (2023) Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer. Cellular Oncology.
Crossref
Rajeswari Raguraman, Dhaval Bhavsar, Dongin Kim, Xiaoyu Ren, Vassilios Sikavitsas, Anupama Munshi & Rajagopal Ramesh. (2023) Tumor-targeted exosomes for delivery of anticancer drugs. Cancer Letters 558, pages 216093.
Crossref
Meiqi Wang, Jiannan Li, Dongxin Wang, Ying Xin & Zhuo Liu. (2023) The effects of mesenchymal stem cells on the chemotherapy of colorectal cancer. Biomedicine & Pharmacotherapy 160, pages 114373.
Crossref
Weiping Zeng, Zhengbo Wen, Honglin Chen & Yuyou Duan. (2022) Exosomes as Carriers for Drug Delivery in Cancer Therapy. Pharmaceutical Research 40:4, pages 873-887.
Crossref
Huichao Fu, Yunjiao Wu, Jianbai Chen, Xing Hu, Xiaoyan Wang & Gongping Xu. (2023) Exosomes and osteosarcoma drug resistance. Frontiers in Oncology 13.
Crossref
Jian Wang, Xiaoqun Li, Sicheng Wang, Jin Cui, Xiaoxiang Ren & Jiacan Su. (2023) Bone‐Targeted Exosomes: Strategies and Applications. Advanced Healthcare Materials, pages 2203361.
Crossref
Xin Zhang, Xutong Zhu, Lifa Huang, Zupeng Chen, Yuchen Wang, Yajun Liu, Ruihan Pan & Ling Lv. (2023) Nano-encapsulated tanshinone IIA in PLGA-PEG-COOH inhibits apoptosis and inflammation in cerebral ischemia/reperfusion injury. Green Processing and Synthesis 12:1.
Crossref
Terjahna Richards, Himaxi Patel, Ketan Patel & Frank Schanne. (2023) Endogenous Lipid Carriers—Bench-to-Bedside Roadblocks in Production and Drug Loading of Exosomes. Pharmaceuticals 16:3, pages 421.
Crossref
Harry V. M. Spiers, Lukas K. J. Stadler, Hugo Smith & Vasilis Kosmoliaptsis. (2023) Extracellular Vesicles as Drug Delivery Systems in Organ Transplantation: The Next Frontier. Pharmaceutics 15:3, pages 891.
Crossref
Vincenza Tinnirello, Nima Rabienezhad Ganji, Carine De Marcos Lousa, Riccardo Alessandro & Stefania Raimondo. (2023) Exploiting the Opportunity to Use Plant-Derived Nanoparticles as Delivery Vehicles. Plants 12:6, pages 1207.
Crossref
Nam HB Tran, Diem DN Nguyen, Ngoc Mai Nguyen, Chau Tran, Ngoc Thanh Nguyen Thi, Duyen TK Ho, Hoai-Nghia Nguyen & Lan N Tu. (2023) Dual-targeting exosomes for improved drug delivery in breast cancer. Nanomedicine 18:7, pages 599-611.
Crossref
Xiaofeng Dai & Kaiyuan Zhu. (2023) Cold atmospheric plasma: Novel opportunities for tumor microenvironment targeting. Cancer Medicine 12:6, pages 7189-7206.
Crossref
Hailong Tian, Jiangjun Cao, Bowen Li, Edouard C. Nice, Haijiao Mao, Yi Zhang & Canhua Huang. (2023) Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment. Bone Research 11:1.
Crossref
Anindya Mukhopadhya, Dimitrios Tsiapalis, Niamh McNamee, Brian Talbot & Lorraine O’Driscoll. (2023) Doxorubicin Loading into Milk and Mesenchymal Stem Cells’ Extracellular Vesicles as Drug Delivery Vehicles. Pharmaceutics 15:3, pages 718.
Crossref
Enguang Yang, Suoshi Jing, Yuhan Wang, Hanzhang Wang, Ronald Rodriguez & Zhiping Wang. (2023) The Role of Mesenchymal Stem Cells and Exosomes in Tumor Development and Targeted Antitumor Therapies. Stem Cells International 2023, pages 1-15.
Crossref
Florian Draguet, Cyril Bouland, Nathan Dubois, Dominique Bron, Nathalie Meuleman, Basile Stamatopoulos & Laurence Lagneaux. (2023) Potential of Mesenchymal Stromal Cell-Derived Extracellular Vesicles as Natural Nanocarriers: Concise Review. Pharmaceutics 15:2, pages 558.
Crossref
Suleiman Alhaji Muhammad, Jaafaru Sani Mohammed & Sulaiman Rabiu. (2023) Exosomes as Delivery Systems for Targeted Tumour Therapy: A Systematic Review and Meta-analysis of In vitro Studies. Pharmaceutical Nanotechnology 11:1, pages 93-104.
Crossref
Chunkang Liu, Kunzhe Wu, Jianyang Li, Xupeng Mu, Huan Gao & Xiaohua Xu. (2023) Nanoparticle-mediated therapeutic management in cholangiocarcinoma drug targeting: Current progress and future prospects. Biomedicine & Pharmacotherapy 158, pages 114135.
Crossref
Jiawen Huang, Yang Xu, Yuxuan Wang, Zhiang Su, Tingting Li, Sisi Wu, Yuheng Mao, Shihua Zhang, Xiquan Weng & Yu Yuan. (2023) Advances in the Study of Exosomes as Drug Delivery Systems for Bone-Related Diseases. Pharmaceutics 15:1, pages 220.
Crossref
Jagannath Mondal, Shameer Pillarisetti, Vijayabhaskarreddy Junnuthula, Monochura Saha, Seung Rim Hwang, In-kyu Park & Yong-kyu Lee. (2023) Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications. Journal of Controlled Release 353, pages 1127-1149.
Crossref
Huali Ye, Linyun Tan, Chongqi Tu & Li Min. (2023) Exosomes in sarcoma: Prospects for clinical applications. Critical Reviews in Oncology/Hematology 181, pages 103895.
Crossref
Tarun Mateti, Shikha Jain, Trisha Biswas, Amrita Dam, Anindita Laha & Goutam Thakur. 2023. Emerging Nanotechnologies for Medical Applications. Emerging Nanotechnologies for Medical Applications 131 164 .
Jiaji Yue, Zhe-Sheng Chen, Xiang-Xi Xu & Shenglong Li. (2022) Functions and therapeutic potentials of exosomes in osteosarcoma. Acta Materia Medica 1:4.
Crossref
Ali Akbari, Fereshteh Nazari-Khanamiri, Mahdi Ahmadi, Maryam Shoaran & Jafar Rezaie. (2022) Engineered Exosomes for Tumor-Targeted Drug Delivery: A Focus on Genetic and Chemical Functionalization. Pharmaceutics 15:1, pages 66.
Crossref
Tianwei Li, Xiaoqing Li, Guiping Han, Ming Liang, Zongrui Yang, Congyi Zhang, Shizhuan Huang, Sheng Tai & Shan Yu. (2022) The Therapeutic Potential and Clinical Significance of Exosomes as Carriers of Drug Delivery System. Pharmaceutics 15:1, pages 21.
Crossref
Sai V. Chitti, Christina Nedeva, Raja Manickam, Pamali Fonseka & Suresh Mathivanan. (2022) Extracellular Vesicles as Drug Targets and Delivery Vehicles for Cancer Therapy. Pharmaceutics 14:12, pages 2822.
Crossref
Shiyang Wang & Yue Shi. (2022) Exosomes Derived from Immune Cells: The New Role of Tumor Immune Microenvironment and Tumor Therapy. International Journal of Nanomedicine Volume 17, pages 6527-6550.
Crossref
Fusheng Zhang, Jinshuai Guo, Zhenghou Zhang, Meiqi Duan, Guang Wang, Yiping Qian, Haiying Zhao, Zhi Yang & Xiaofeng Jiang. (2022) Application of engineered extracellular vesicles for targeted tumor therapy. Journal of Biomedical Science 29:1.
Crossref
Qi Chen, Di Wu, Yi Wang & Zhong Chen. (2022) Exosomes as Novel Delivery Systems for Application in Traditional Chinese Medicine. Molecules 27:22, pages 7789.
Crossref
Mahdi Ahmadi, Monireh Mahmoodi, Maryam Shoaran, Fereshteh Nazari-Khanamiri & Jafar Rezaie. (2022) Harnessing Normal and Engineered Mesenchymal Stem Cells Derived Exosomes for Cancer Therapy: Opportunity and Challenges. International Journal of Molecular Sciences 23:22, pages 13974.
Crossref
Alina A. Bagdasaryan, Vladimir N. Chubarev, Elena A. Smolyarchuk, Vladimir N. Drozdov, Ivan I. Krasnyuk, Junqi Liu, Ruitai Fan, Edmund Tse, Evgenia V. Shikh & Olga A. Sukocheva. (2022) Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy. Cancers 14:21, pages 5436.
Crossref
Nashmin Fayazi Hosseini, Razieh Amini, Mohammad Ramezani, Massoud Saidijam, Seyed Mahmoud Hashemi & Rezvan Najafi. (2022) AS1411 aptamer-functionalized exosomes in the targeted delivery of doxorubicin in fighting colorectal cancer. Biomedicine & Pharmacotherapy 155, pages 113690.
Crossref
Suhail Ahmad Mir, Laraibah Hamid, Ghulam Nabi Bader, Ambreen Shoaib, Mohamed Rahamathulla, Mohammad Y. Alshahrani, Prawez Alam & Faiyaz Shakeel. (2022) Role of Nanotechnology in Overcoming the Multidrug Resistance in Cancer Therapy: A Review. Molecules 27:19, pages 6608.
Crossref
Tianjiao Geng, Mingtan Tang, Song Yee Paek, Euphemia Leung, Larry W. Chamley & Zimei Wu. (2022) A simple approach to re-engineering small extracellular vesicles to circumvent endosome entrapment. International Journal of Pharmaceutics 626, pages 122153.
Crossref
Serena Lucotti, Candia M Kenific, Haiying Zhang & David Lyden. (2022) Extracellular vesicles and particles impact the systemic landscape of cancer. The EMBO Journal 41:18.
Crossref
Xia Wang, Lu Tian, Jingyi Lu & Irene Oi-Lin Ng. (2022) Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle. Oncogenesis 11:1.
Crossref
Zhengjun Lin, Yanlin Wu, Yiting Xu, Guoqing Li, Zhihong Li & Tang Liu. (2022) Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential. Molecular Cancer 21:1.
Crossref
Guoxia Zhang, Xinyu Yang, Xin Su, Na An, Fan Yang, Xinye Li, Yuchen Jiang & Yanwei Xing. (2022) Understanding the Protective Role of Exosomes in Doxorubicin-Induced Cardiotoxicity. Oxidative Medicine and Cellular Longevity 2022, pages 1-14.
Crossref
Kouta Yamashiro, Tomofumi Hamada, Kazuki Mori, Keitaro Nishi, Maya Nakamura, Mahiro Beppu, Akihiko Tanaka, Hiroshi Hijioka, Yoshiaki Kamikawa & Tsuyoshi Sugiura. (2022) Exosome-Derived microRNAs from Mouthrinse Have the Potential to Be Novel Biomarkers for Sjögren Syndrome. Journal of Personalized Medicine 12:9, pages 1483.
Crossref
Huali Ye, Xin Hu, Yang Wen, Chongqi Tu, Francis Hornicek, Zhenfeng Duan & Li Min. (2022) Exosomes in the tumor microenvironment of sarcoma: from biological functions to clinical applications. Journal of Nanobiotechnology 20:1.
Crossref
Zhenggang Wang, Haokun Mo, Zhiyi He, Anmin Chen & Peng Cheng. (2022) Extracellular vesicles as an emerging drug delivery system for cancer treatment: Current strategies and recent advances. Biomedicine & Pharmacotherapy 153, pages 113480.
Crossref
Jafar Rezaie, Vahid Nejati, Monireh Mahmoodi & Mahdi Ahmadi. (2022) Mesenchymal stem cells derived extracellular vesicles: A promising nanomedicine for drug delivery system. Biochemical Pharmacology 203, pages 115167.
Crossref
Bing Wang, Baichun Wang, Quanshou Feng, Xiang Fang, Xinhua Dai, Yinghua Yan & Chuan-Fan Ding. (2022) Magnetic guanidyl–functionalized covalent organic framework composite: a platform for specific capture and isolation of phosphopeptides and exosomes. Microchimica Acta 189:9.
Crossref
Xiaofeng Dai, Yongju Ye & Fule He. (2022) Emerging innovations on exosome-based onco-therapeutics. Frontiers in Immunology 13.
Crossref
Abhishek Dutta & Swastika Paul. (2022) Advancement in exosome-based cancer therapeutics: A new era in cancer treatment. Frontiers in Nanotechnology 4.
Crossref
Hongxiang Wei, Fei Chen, Jinyuan Chen, Huangfeng Lin, Shenglin Wang, Yunqing Wang, Chaoyang Wu, Jianhua Lin & Guangxian Zhong. (2022) Mesenchymal Stem Cell Derived Exosomes as Nanodrug Carrier of Doxorubicin for Targeted Osteosarcoma Therapy via SDF1-CXCR4 Axis. International Journal of Nanomedicine Volume 17, pages 3483-3495.
Crossref
Shuhang Wang, Keman Cheng, Kun Chen, Chen Xu, Peiwen Ma, Guohui Dang, Yuqi Yang, Qi Lei, Huiyao Huang, Yue Yu, Yuan Fang, Qiyu Tang, Ning Jiang, Huilei Miao, Funan Liu, Xiao Zhao & Ning Li. (2022) Nanoparticle-based medicines in clinical cancer therapy. Nano Today 45, pages 101512.
Crossref
Reyhaneh Toghiani, Samira Sadat Abolmaali, Haniyeh Najafi & Ali Mohammad Tamaddon. (2022) Bioengineering exosomes for treatment of organ ischemia-reperfusion injury. Life Sciences 302, pages 120654.
Crossref
Xinyu Li, Qing Fan, Xueqiang Peng, Shuo Yang, Shibo Wei, Jingang Liu, Liang Yang & Hangyu Li. (2022) Mesenchymal/stromal stem cells: necessary factors in tumour progression. Cell Death Discovery 8:1.
Crossref
Liju Nie, Siming Xin, Jiusheng Zheng, Yong Luo, Yang Zou, Xianxian Liu, Huayan Chen, Xiaozhen Lei, Xiaoming Zeng & Hua Lai. (2022) DIA-based proteomics analysis of serum-derived exosomal proteins as potential candidate biomarkers for intrahepatic cholestasis in pregnancy. Archives of Gynecology and Obstetrics 308:1, pages 79-89.
Crossref
Anita Raj Panigrahi, Lankalapalli Srinivas & Jagadeesh Panda. (2022) Exosomes: Insights and therapeutic applications in cancer. Translational Oncology 21, pages 101439.
Crossref
Yingying Jiang, Jiadong Li, Xu Xue, Zhifeng Yin, Ke Xu & Jiacan Su. (2022) Engineered extracellular vesicles for bone therapy. Nano Today 44, pages 101487.
Crossref
Lianlian Yang, Junhong Ling, Nan Wang, Yongjun Jiang, Yuqing Lu, Li-Ye Yang & Xiao–kun Ouyang. (2022) Delivery of doxorubicin by dual responsive carboxymethyl chitosan based nanogel and in vitro performance. Materials Today Communications 31, pages 103781.
Crossref
Zarema Gilazieva, Aleksei Ponomarev, Albert Rizvanov & Valeriya Solovyeva. (2022) The Dual Role of Mesenchymal Stromal Cells and Their Extracellular Vesicles in Carcinogenesis. Biology 11:6, pages 813.
Crossref
Shenyuan Chen, Fengtian Sun, Hui Qian, Wenrong Xu & Jiajia Jiang. (2022) Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell-Derived Exosomes in Cell-Free Therapy. Stem Cells International 2022, pages 1-18.
Crossref
Mingzheng Chen, Yangyang Li, Ningfu Ma & Jinfeng Zang. (2022) Mesenchymal stem cell‑derived exosomes loaded with 5‑Fu against cholangiocarcinoma in vitro . Molecular Medicine Reports 25:6.
Crossref
Zhongyang Zhang, Jun Zhou, Chuang Liu, Jiaming Zhang, Yo Shibata, Na Kong, Claudia Corbo, Mitchel B. Harris & Wei Tao. (2022) Emerging biomimetic nanotechnology in orthopedic diseases: progress, challenges, and opportunities. Trends in Chemistry 4:5, pages 420-436.
Crossref
Erika L. Cyphert, Nithya Kanagasegar, Ningjing Zhang, Greg D. Learn & Horst A. von Recum. (2022) PMMA Bone Cement Composite Functions as an Adjuvant Chemotherapeutic Platform for Localized and Multi‐Window Release during Bone Reconstruction. Macromolecular Bioscience 22:5, pages 2100415.
Crossref
María Cecilia Sanmartin, Francisco Raúl Borzone, María Belén Giorello, Gustavo Yannarelli & Norma Alejandra Chasseing. (2022) Mesenchymal Stromal Cell-Derived Extracellular Vesicles as Biological Carriers for Drug Delivery in Cancer Therapy. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Débora Ferreira, João Nuno Moreira & Lígia R. Rodrigues. (2022) New advances in exosome-based targeted drug delivery systems. Critical Reviews in Oncology/Hematology 172, pages 103628.
Crossref
Sanjana Vig & Maria Helena Fernandes. (2022) Bone Cell Exosomes and Emerging Strategies in Bone Engineering. Biomedicines 10:4, pages 767.
Crossref
Kai Qiao, Lu Xu, Junnan Tang, Qiguang Wang, Khoon S. Lim, Gary Hooper, Tim B. F. Woodfield, Guozhen Liu, Kang Tian, Weiguo Zhang & Xiaolin Cui. (2022) The advances in nanomedicine for bone and cartilage repair. Journal of Nanobiotechnology 20:1.
Crossref
Mouzhang Huang, Limei Zeng, Rongping Zhu, Gongqun Chen, Haijian Wu, Bin Fan, Changtie Liu, Bowen Guo & Hongfa Zhong. (2022) Hyaluronic Acid Stabilized Doxorubicin Nano-Precipitations for Osteosarcoma Treatment. Journal of Biomaterials and Tissue Engineering 12:3, pages 500-505.
Crossref
Chan Shan, Yan Liang, Hongjing Cai, Fei Wang, Xinzhe Chen, Qikun Yin, Kun Wang & Yin Wang. (2022) Emerging function and clinical significance of extracellular vesicle noncoding RNAs in lung cancer. Molecular Therapy - Oncolytics 24, pages 814-833.
Crossref
Kunzhe Wu, Beibei Yu, Di Li, Yangyang Tian, Yan Liu & Jinlan Jiang. (2022) Recent Advances in Nanoplatforms for the Treatment of Osteosarcoma. Frontiers in Oncology 12.
Crossref
Fusheng Zhang, Jinshuai Guo, Zhenghou Zhang, Yiping Qian, Guang Wang, Meiqi Duan, Haiying Zhao, Zhi Yang & Xiaofeng Jiang. (2022) Mesenchymal stem cell-derived exosome: A tumor regulator and carrier for targeted tumor therapy. Cancer Letters 526, pages 29-40.
Crossref
Sirine Yassine & Nada Alaaeddine. (2021) Mesenchymal Stem Cell Exosomes and Cancer: Controversies and Prospects. Advanced Biology 6:2.
Crossref
Carla Vicinanza, Elisabetta Lombardi, Francesco Da Ros, Miriam Marangon, Cristina Durante, Mario Mazzucato & Francesco Agostini. (2022) Modified mesenchymal stem cells in cancer therapy: A smart weapon requiring upgrades for wider clinical applications. World Journal of Stem Cells 14:1, pages 54-75.
Crossref
Yan Zhou, Lu-Lu Wen, Yan-Fei Li, Kai-Min Wu, Ran-Ran Duan, Yao-Bing Yao, Li-Jun Jing, Zhe Gong, Jun-Fang Teng & Yan-Jie Jia. (2022) Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis. Neural Regeneration Research 17:1, pages 194.
Crossref
Ana Santos, Cátia Domingues, Ivana Jarak, Francisco Veiga & Ana Figueiras. (2022) Osteosarcoma from the unknown to the use of exosomes as a versatile and dynamic therapeutic approach. European Journal of Pharmaceutics and Biopharmaceutics 170, pages 91-111.
Crossref
Tania Limongi, Francesca Susa, Monica Marini, Marco Allione, Bruno Torre, Roberto Pisano & Enzo di Fabrizio. (2021) Lipid-Based Nanovesicular Drug Delivery Systems. Nanomaterials 11:12, pages 3391.
Crossref
Chaoqi Li, Xiangbo Gou & Hui Gao. (2021) Doxorubicin nanomedicine based on ginsenoside Rg1 with alleviated cardiotoxicity and enhanced antitumor activity. Nanomedicine 16:29, pages 2587-2604.
Crossref
Zhe Cheng, Maoyu Li, Raja Dey & Yongheng Chen. (2021) Nanomaterials for cancer therapy: current progress and perspectives. Journal of Hematology & Oncology 14:1.
Crossref
Shenglong Li. (2021) The basic characteristics of extracellular vesicles and their potential application in bone sarcomas. Journal of Nanobiotechnology 19:1.
Crossref
Viviana De Martino, Michela Rossi, Giulia Battafarano, Jessica Pepe, Salvatore Minisola & Andrea Del Fattore. (2021) Extracellular Vesicles in Osteosarcoma: Antagonists or Therapeutic Agents?. International Journal of Molecular Sciences 22:22, pages 12586.
Crossref
Yao Sun, Guoliang Liu, Kai Zhang, Qian Cao, Tongjun Liu & Jiannan Li. (2021) Mesenchymal stem cells-derived exosomes for drug delivery. Stem Cell Research & Therapy 12:1.
Crossref
Lingkai Yang, Xin Huang, Haoyu Guo, Lutong Wang, Wenbo Yang, Wei Wu, Doudou Jing & Zengwu Shao. (2021) Exosomes as Efficient Nanocarriers in Osteosarcoma: Biological Functions and Potential Clinical Applications. Frontiers in Cell and Developmental Biology 9.
Crossref
Huizhi Chen, Liyan Wang, Xinling Zeng, Herbert Schwarz, Himansu Sekhar Nanda, Xinsheng Peng & Yubin Zhou. (2021) Exosomes, a New Star for Targeted Delivery. Frontiers in Cell and Developmental Biology 9.
Crossref
Shilpa Lekhraj Peswani Sajnani, Yunyue Zhang & Driton Vllasaliu. (2021) Exosome-based therapies for mucosal delivery. International Journal of Pharmaceutics 608, pages 121087.
Crossref
Eugenia Romano, Paolo Antonio Netti & Enza Torino. (2021) A High Throughput Approach Based on Dynamic High Pressure for the Encapsulation of Active Compounds in Exosomes for Precision Medicine. International Journal of Molecular Sciences 22:18, pages 9896.
Crossref
Nika Kučuk, Mateja Primožič, Željko Knez & Maja Leitgeb. (2021) Exosomes Engineering and Their Roles as Therapy Delivery Tools, Therapeutic Targets, and Biomarkers. International Journal of Molecular Sciences 22:17, pages 9543.
Crossref
Zhenzhen Han, Cheng Peng, Jia Yi, Yiwen Wang, Qi Liu, Yi Yang, Shuping Long, Liang Qiao & Yuhui Shen. (2021) Matrix-assisted laser desorption ionization mass spectrometry profiling of plasma exosomes evaluates osteosarcoma metastasis. iScience 24:8, pages 102906.
Crossref
Masomeh Maleki, Asal Golchin, Forough Alemi, Simin Younesi, Zatollah Asemi, Samira Javadi, Payam Ali Khiavi, Jafar Soleinmapour & Bahman Yousefi. (2021) Cytotoxicity and apoptosis of nanoparticles on osteosarcoma cells using doxorubicin and methotrexate: A systematic review. European Journal of Pharmacology 904, pages 174131.
Crossref
Benilde Adriano, Nycol M. Cotto, Neeraj Chauhan, Meena Jaggi, Subhash C. Chauhan & Murali M. Yallapu. (2021) Milk exosomes: Nature's abundant nanoplatform for theranostic applications. Bioactive Materials 6:8, pages 2479-2490.
Crossref
Alok Raghav, Prashant Tripathi, Brijesh Kumar Mishra, Goo-Bo Jeong, Shahid Banday, Kirti Amresh Gautam, Qazi Noorul Mateen, Prem Singh, Manish Singh, Akhil Singla & Jamal Ahmad. (2021) Mesenchymal Stromal Cell-Derived Tailored Exosomes Treat Bacteria-Associated Diabetes Foot Ulcers: A Customized Approach From Bench to Bed. Frontiers in Microbiology 12.
Crossref
Ali Hassanzadeh, Amjad Hussein Altajer, Heshu Sulaiman Rahman, Marwan Mahmood Saleh, Dmitry O. Bokov, Walid Kamal Abdelbasset, Faroogh Marofi, Majid Zamani, Yoda Yaghoubi, Mahboubeh Yazdanifar, Yashwant Pathak, Max Stanley Chartrand & Mostafa Jarahian. (2021) Mesenchymal Stem/Stromal Cell-Based Delivery: A Rapidly Evolving Strategy for Cancer Therapy. Frontiers in Cell and Developmental Biology 9.
Crossref
Zixuan Sun, Jiaxin Zhang, Jiali Li, Mi Li, Jing Ge, Peipei Wu, Benshuai You & Hui Qian. (2021) Roles of Mesenchymal Stem Cell-Derived Exosomes in Cancer Development and Targeted Therapy. Stem Cells International 2021, pages 1-10.
Crossref
Xin-Hui Cao, Ming-Xing Liang, Yang Wu, Kai Yang, Jin-Hai Tang & Wei Zhang. (2021) Extracellular vesicles as drug vectors for precise cancer treatment. Nanomedicine 16:17, pages 1519-1537.
Crossref
Haixia Zhu, Deta Chen, Xiaoliang Xie, Yumei Li & Tianyou Fan. (2021) Melittin inhibits lung metastasis of human osteosarcoma: Evidence of wnt/β-catenin signaling pathway participation. Toxicon 198, pages 132-142.
Crossref
Lingyun Wang, Zhichao Sun & Hongmei Wang. (2021) Extracellular vesicles and the regulation of tumor immunity: Current progress and future directions. Journal of Cellular Biochemistry 122:7, pages 760-769.
Crossref
Maobin Xie, Di Wu, Guangmeng Li, Jingbo Yang & Yu Shrike Zhang. (2021) Exosomes targeted towards applications in regenerative medicine. Nano Select 2:5, pages 880-908.
Crossref
Zafer Cetin, Eyup I. Saygili, Gokhan Görgisen & Emel Sokullu. (2021) Preclinical Experimental Applications of miRNA Loaded BMSC Extracellular Vesicles. Stem Cell Reviews and Reports 17:2, pages 471-501.
Crossref
Jing Gao, Jinhui Huang, Rui Shi, Jiawei Wei, Xiaoyu Lei, Yichen Dou, Yubao Li, Yi Zuo & Jidong Li. (2021) Loading and Releasing Behavior of Selenium and Doxorubicin Hydrochloride in Hydroxyapatite with Different Morphologies. ACS Omega 6:12, pages 8365-8375.
Crossref
Domenica Giannandrea, Valentina Citro, Elena Lesma, Monica Bignotto, Natalia Platonova & Raffaella Chiaramonte. (2021) Restoring Tissue Homeostasis at Metastatic Sites: A Focus on Extracellular Vesicles in Bone Metastasis. Frontiers in Oncology 11.
Crossref
Hang Song, Bin Liu, Bin Dong, Jing Xu, Hui Zhou, Sha Na, Yanyan Liu, Yunxia Pan, Fengyuan Chen, Lu Li & Jinghui Wang. (2021) Exosome-Based Delivery of Natural Products in Cancer Therapy. Frontiers in Cell and Developmental Biology 9.
Crossref
Hyoung-Jun Kim, Do-Gak Jeung & Jae-Min Oh. (2021) Boosting the anticancer activity of doxorubicin with a layered double hydroxide nanocarrier. Applied Clay Science 203, pages 106000.
Crossref
Ming Dong, Saixuan Wu, Huijun Xu, Xinxin Yu, Lina Wang, Hua Bai & Weidong Niu. (2021) FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Mahmood Barani, Mahwash Mukhtar, Abbas Rahdar, Saman Sargazi, Sadanand Pandey & Misook Kang. (2021) Recent Advances in Nanotechnology-Based Diagnosis and Treatments of Human Osteosarcoma. Biosensors 11:2, pages 55.
Crossref
Yohan Han, Timothy W. Jones, Saugata Dutta, Yin Zhu, Xiaoyun Wang, S. Priya Narayanan, Susan C. Fagan & Duo Zhang. (2021) Overview and Update on Methods for Cargo Loading into Extracellular Vesicles. Processes 9:2, pages 356.
Crossref
Jie Shi, Yu-Chen Zhao, Zhi-Fang Niu, Hao-Jun Fan, Shi-Ke Hou, Xiao-Qin Guo, Lu Sang & Qi Lv. (2021) Mesenchymal stem cell-derived small extracellular vesicles in the treatment of human diseases: Progress and prospect. World Journal of Stem Cells 13:1, pages 49-63.
Crossref
Carmen Gutierrez‐Millan, Clara Calvo Díaz, José M. Lanao & Clara I. Colino. (2020) Advances in Exosomes‐Based Drug Delivery Systems. Macromolecular Bioscience 21:1.
Crossref
Liansheng Sha, Deying Ma & Cuili Chen. (2020) Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway. Aging 12:23, pages 23598-23608.
Crossref
Jun Wang, Hongliang Zhang, Xin Sun, Xiaofang Wang, Tingting Ren, Yi Huang, Ranxin Zhang, Bingxin Zheng & Wei Guo. (2020) Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients. Journal of Nanobiotechnology 18:1.
Crossref
Laura Cabeza, Gloria Perazzoli, Mercedes Peña, Ana Cepero, Cristina Luque, Consolacion Melguizo & Jose Prados. (2020) Cancer therapy based on extracellular vesicles as drug delivery vehicles. Journal of Controlled Release 327, pages 296-315.
Crossref
Bart de Jong, Eric Raul Barros, Joost G. J. Hoenderop & Juan Pablo Rigalli. (2020) Recent Advances in Extracellular Vesicles as Drug Delivery Systems and Their Potential in Precision Medicine. Pharmaceutics 12:11, pages 1006.
Crossref
Shengyang Fu, Yi Wang, Xiaohuan Xia & Jialin C. Zheng. (2020) Exosome engineering: Current progress in cargo loading and targeted delivery. NanoImpact 20, pages 100261.
Crossref
Simone Pisano, Irene Pierini, Jianhua Gu, Andrea Gazze, Lewis Webb Francis, Deyarina Gonzalez, Robert Steven Conlan & Bruna Corradetti. (2020) Immune (Cell) Derived Exosome Mimetics (IDEM) as a Treatment for Ovarian Cancer. Frontiers in Cell and Developmental Biology 8.
Crossref
Batla Al-Sowayan, Farah Alammari & Alaa Alshareeda. (2020) Preparing the Bone Tissue Regeneration Ground by Exosomes: From Diagnosis to Therapy. Molecules 25:18, pages 4205.
Crossref
Marie Maumus, Pauline Rozier, Jérémy Boulestreau, Christian Jorgensen & Danièle Noël. (2020) Mesenchymal Stem Cell-Derived Extracellular Vesicles: Opportunities and Challenges for Clinical Translation. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Vajihe Taghdiri Nooshabadi, Mehdi Khanmohammadi, Shilan Shafei, Hamid Reza Banafshe, Ziba Veisi Malekshahi, Somayeh Ebrahimi-Barough & Jafar Ai. (2020) Impact of atorvastatin loaded exosome as an anti-glioblastoma carrier to induce apoptosis of U87 cancer cells in 3D culture model. Biochemistry and Biophysics Reports 23, pages 100792.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.