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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

Zein-alpha lipoic acid-loaded nanoparticles to enhance the oral bioavailability of dapoxetine: optimization and clinical pharmacokinetic evaluation

Khalid M El-Say1 Nanotechnology Laboratory, Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah21589, Saudi Arabia;2 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo11651, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5539-3193
ORCID Icon,
Osama AA Ahmed1 Nanotechnology Laboratory, Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah21589, Saudi Arabia;3 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia61519, EgyptORCID Iconhttps://orcid.org/0000-0002-3204-381X
ORCID Icon,
Amir I Mohamed4 Department of Pharmaceutics and Industrial Pharmacy, Military Medical Academy, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0002-2053-2050
ORCID Icon,
Martin K Safo5 Department of Medicinal Chemistry, and the Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA23298, USAORCID Iconhttps://orcid.org/0000-0002-9536-1743
ORCID Icon &
Abdelsattar M Omar6 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah21589, Saudi Arabia;7 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo11884, Egypt
Pages 7461-7473 | Published online: 12 Sep 2019

Citations (7)

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Shimul Halder, Yasuhiko Mibe, Shingo Rikimura, Koichi Kuromi, Hideyuki Sato & Satomi Onoue. (2022) Strategic application of liposomal system to R-α-lipoic acid for the improvement of nutraceutical properties. Drug Development and Industrial Pharmacy 48:6, pages 239-246.
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Osama A A Ahmed, Usama A Fahmy, Rana Bakhaidar, Mohamed A El-Moselhy, Mohamed A Alfaleh, Al-Shaimaa F Ahmed, Asmaa S A Hammad, Hibah Aldawsari & Nabil A Alhakamy. (2020) Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats. International Journal of Nanomedicine 15, pages 2529-2539.
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Articles from other publishers (5)

Amira E. El-Nahas, Heba M. Elbedaiwy, Inas M. Masoud, Rania G. Aly, Maged W. Helmy & Amal H. El-Kamel. (2023) Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy. European Journal of Pharmaceutics and Biopharmaceutics 188, pages 182-200.
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Silvia Voci, Agnese Gagliardi, Maria Cristina Salvatici, Massimo Fresta & Donato Cosco. (2022) Influence of the Dispersion Medium and Cryoprotectants on the Physico-Chemical Features of Gliadin- and Zein-Based Nanoparticles. Pharmaceutics 14:2, pages 332.
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Usama A. Fahmy, Osama A.A. Ahmed, Mohamed A. El-mose, Hani Z. Asfour & Nabil A. Alhakamy. (2020) Thymoquinone Loaded Zein Nanoparticles Improves the Cytotoxicity against Breast Cancer Cells. International Journal of Pharmacology 16:8, pages 554-561.
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Hibah M. Aldawsari, Usama A. Fahmy, Fathy Abd-Allah & Osama A. A. Ahmed. (2020) Formulation and Optimization of Avanafil Biodegradable Polymeric Nanoparticles: A Single-Dose Clinical Pharmacokinetic Evaluation. Pharmaceutics 12:6, pages 596.
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Tarek A. Ahmed, Asmaa M. S. Alay, Solomon Z. Okbazghi & Nabil A. Alhakamy. (2020) Two-Step Optimization to Develop a Transdermal Film Loaded With Dapoxetine Nanoparticles: A Promising Technique to Improve Drug Skin Permeation. Dose-Response 18:2, pages 155932582092385.
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