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International Journal of Nanomedicine Volume 14, 2019 - Issue
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Original Research

In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG

Alicja Karabasz1 Department of Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland
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Krzysztof Szczepanowicz2 Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Kraków, PolandORCID Iconhttps://orcid.org/0000-0002-9927-5869
ORCID Icon,
Agnieszka Cierniak3 Department of General Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland;4 Department of Biochemistry, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, Kraków, PolandORCID Iconhttps://orcid.org/0000-0001-6537-2954
ORCID Icon,
Renata Mezyk-Kopec1 Department of Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, PolandORCID Iconhttps://orcid.org/0000-0002-0239-0589
ORCID Icon,
Grzegorz Dyduch5 Department of Pathomorphology, Jagiellonian University Medical College, Kraków, Poland
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Marta Szczęch2 Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Kraków, PolandORCID Iconhttps://orcid.org/0000-0003-3013-6585
ORCID Icon,
Joanna Bereta1 Department of Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, PolandORCID Iconhttps://orcid.org/0000-0001-7930-2770
ORCID Icon &
Monika Bzowska1 Department of Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, PolandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1921-0334
ORCID Icon show all
Pages 9587-9602 | Published online: 05 Dec 2019

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Jia Yin, Jia Gao, Shuang Liu, Ligang Hu, Chunyang Liao & Guibin Jiang. (2023) Addressing the intersection of COVID-19 and metal nanoparticle use: Risks and control strategies. Critical Reviews in Environmental Science and Technology 0:0, pages 1-23.
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Alicja Hinz, Marta Szczęch, Krzysztof Szczepanowicz & Monika Bzowska. (2022) Fluorophore Localization Determines the Results of Biodistribution of Core-Shell Nanocarriers. International Journal of Nanomedicine 17, pages 577-588.
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Articles from other publishers (21)

Ahmed M. Abu-Dief, Mosa Alsehli & Aziz Awaad. (2023) The bioreaction and immune responses of PEG-coated silica NPs and the role of the surface density coating after oral administration into mice. Applied Nanoscience 13:8, pages 5563-5578.
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Nathaly Vasquez-Martínez, Daniel Guillen, Silvia Andrea Moreno-Mendieta, Sergio Sanchez & Romina Rodríguez-Sanoja. (2023) The Role of Mucoadhesion and Mucopenetration in the Immune Response Induced by Polymer-Based Mucosal Adjuvants. Polymers 15:7, pages 1615.
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María Javiera Alvarez-Figueroa, Diego A. Alarcón & José Vicente González-Aramúndiz. (2022) Effect of zeta potential of innovative lipid nanocapsules on triamcinolone transdermal delivery. Drug Delivery and Translational Research 12:11, pages 2740-2750.
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Courtney van Ballegooie, Nicole Wretham, Tanya Ren, Ioana-Mihaela Popescu, Donald T. Yapp & Marcel B. Bally. (2022) PEG Conjugated Zein Nanoparticles for In Vivo Use. Pharmaceutics 14:9, pages 1831.
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Donghui Song & Qiaobing Xu. (2022) Engineering a Nano/Biointerface for Cell and Organ-Selective Drug Delivery. Langmuir 38:30, pages 9092-9098.
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T. Ngake, S. Nqayi, M. Gulumian, S. Cronjé & R.A. Harris. (2022) Recent developments in computational and experimental studies of physicochemical properties of Au and Ag nanostructures on cellular uptake and nanostructure toxicity. Biochimica et Biophysica Acta (BBA) - General Subjects 1866:8, pages 130170.
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Qingqing Xiao, Makhloufi Zoulikha, Min Qiu, Chao Teng, Chenshi Lin, Xiaotong Li, Marwa A. Sallam, Qiaobing Xu & Wei He. (2022) The effects of protein corona on in vivo fate of nanocarriers. Advanced Drug Delivery Reviews 186, pages 114356.
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Wenyu Song, Yangmeihui Song, Qian Li, Chunhai Fan, Xiaoli Lan & Dawei Jiang. (2022) Advances in aptamer-based nuclear imaging. European Journal of Nuclear Medicine and Molecular Imaging 49:8, pages 2544-2559.
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Roshani R. Pagar, Shubham R. Musale, Ganesh Pawar, Deepak Kulkarni & Prabhanjan S. Giram. (2022) Comprehensive Review on the Degradation Chemistry and Toxicity Studies of Functional Materials. ACS Biomaterials Science & Engineering 8:6, pages 2161-2195.
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Jussânia Almeida Gnoatto, Ana Moira Morás, João Vitor de Oliveira, Eduarda Arndt, Alexsandro Dallegrave, Ana Cristina Borba da Cunha, Dinara Jaqueline Moura & João Henrique Zimnoch dos Santos. (2022) PEGylated and zwitterated silica nanoparticles as doxorubicin carriers applied in a breast cancer cell line: Effects on protein corona formation. Journal of Drug Delivery Science and Technology 71, pages 103325.
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Yongchun Wei, Lingxiu Kong, Huimin Chen, Yuanyuan Liu, Yifei Xu, Han Wang, Guiqian Fang, Xintian Shao, Fei Liu, Yanfeng Wang & Qixin Chen. (2022) Super-resolution image-based tracking of drug distribution in mitochondria of a label-free naturally derived drug molecules. Chemical Engineering Journal 429, pages 132134.
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Baozhao Xie, Keqian Du, Fujian Huang, Zhiming Lin & Linping Wu. (2022) Cationic Nanomaterials for Autoimmune Diseases Therapy. Frontiers in Pharmacology 12.
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Da Shi, Damian Beasock, Adam Fessler, Janos Szebeni, Julia Y. Ljubimova, Kirill A. Afonin & Marina A. Dobrovolskaia. (2022) To PEGylate or not to PEGylate: Immunological properties of nanomedicine’s most popular component, polyethylene glycol and its alternatives. Advanced Drug Delivery Reviews 180, pages 114079.
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Magdaléna Kapustová, Andrea Puškárová, Mária Bučková, Giuseppe Granata, Edoardo Napoli, Adriana Annušová, Monika Mesárošová, Katarína Kozics, Domenico Pangallo & Corrada Geraci. (2021) Biofilm inhibition by biocompatible poly(ε-caprolactone) nanocapsules loaded with essential oils and their cyto/genotoxicity to human keratinocyte cell line. International Journal of Pharmaceutics 606, pages 120846.
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Teresa Basinska, Mariusz Gadzinowski, Damian Mickiewicz & Stanislaw Slomkowski. (2021) Functionalized Particles Designed for Targeted Delivery. Polymers 13:12, pages 2022.
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Francisco G. Blanco, Natalia Hernández, Virginia Rivero-Buceta, Beatriz Maestro, Jesús M. Sanz, Aránzazu Mato, Ana M. Hernández-Arriaga & M. Auxiliadora Prieto. (2021) From Residues to Added-Value Bacterial Biopolymers as Nanomaterials for Biomedical Applications. Nanomaterials 11:6, pages 1492.
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Wenjia Wang, Qianfeng Zhang, Zhiqian Li, Jing Zhang, Dayi Pan, Bing Wang, Hongyan Zhu, Hu Zhang, Zhongwei Gu & Kui Luo. (2021) Dendron‐Functionalized Polyglutamate‐Pyropheophorbide‐a Conjugates as Nanomedicines for Breast Cancer Photodynamic Therapy. Macromolecular Rapid Communications 42:9, pages 2100013.
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Amira M. G. Darwish, Tarek N. Soliman, Hassan A. Elhendy & Wedad M. El-Kholy. (2021) Nano-encapsulated Iron and Folic Acid-Fortified Functional Yogurt Enhance Anemia in Albino Rats. Frontiers in Nutrition 8.
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Tatiana Borodina, Anastasia Gileva, Roman Akasov, Daria Trushina, Sergey Burov, Natalia Klyachko, Yorexis González‐Alfaro, Tatiana Bukreeva & Elena Markvicheva. (2020) Fabrication and evaluation of nanocontainers for lipophilic anticancer drug delivery in 3D in vitro model . Journal of Biomedical Materials Research Part B: Applied Biomaterials 109:4, pages 527-537.
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Min Liu, Mengmeng Shu, Jiaqing Yan, Xuxu Liu, Ruifeng Wang, Zhiyao Hou & Jun Lin. (2021) Luminescent net-like inorganic scaffolds with europium-doped hydroxyapatite for enhanced bone reconstruction. Nanoscale 13:2, pages 1181-1194.
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Xiaoyi Wang, Nana Meng, Songli Wang, Linwei Lu, Huan Wang, Changyou Zhan, Diane J. Burgess & Weiyue Lu. (2020) Factors Influencing the Immunogenicity and Immunotoxicity of Cyclic RGD Peptide-Modified Nanodrug Delivery Systems. Molecular Pharmaceutics 17:9, pages 3281-3290.
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