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International Journal of Nanomedicine Volume 15, 2020 - Issue
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Original Research

Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate

Ru Sun1 Department of Pharmacy, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, People’s Republic of China
,
Chengwu Shen1 Department of Pharmacy, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, People’s Republic of China
,
Shumaila Shafique2 Faculty of Pharmaceutical Sciences, Dow College of Pharmacy, Dow University of Health Sciences, Karachi 74200, Pakistan
,
Omer Mustapha2 Faculty of Pharmaceutical Sciences, Dow College of Pharmacy, Dow University of Health Sciences, Karachi 74200, PakistanORCID Iconhttps://orcid.org/0000-0001-7801-630X
ORCID Icon,
Talib Hussain3 Department of Pharmacy, COMSATS University Islamabad, Lahore 54000, Pakistan
,
Ikram Ullah Khan4 Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad 38000, PakistanORCID Iconhttps://orcid.org/0000-0002-8200-0180
ORCID Icon,
Yasir Mehmood4 Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad 38000, PakistanORCID Iconhttps://orcid.org/0000-0002-7786-2755
ORCID Icon,
Khaleeq Anwer5 Office of Chief Executive Officer, District Health Authority, Pakpattan 57400, Pakistan
,
Yasser Shahzad3 Department of Pharmacy, COMSATS University Islamabad, Lahore 54000, PakistanORCID Iconhttps://orcid.org/0000-0002-0974-2954
ORCID Icon &
Abid Mehmood Yousaf3 Department of Pharmacy, COMSATS University Islamabad, Lahore 54000, PakistanCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-7866-9474
ORCID Icon show all
Pages 705-715 | Published online: 31 Jan 2020

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Misbah Hameed, Akhtar Rasul, Ahsan Nazir, Abid Mehmood Yousaf, Talib Hussain, Ikram Ullah Khan, Ghulam Abbas, Sharjeel Abid, Qurrat ul Ain Yousafi, Muhammad Usman Ghori & Yasser Shahzad. (2021) Moxifloxacin-loaded electrospun polymeric composite nanofibers-based wound dressing for enhanced antibacterial activity and healing efficacy. International Journal of Polymeric Materials and Polymeric Biomaterials 70:17, pages 1271-1279.
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Lin Zhao, Omer Mustapha, Shumaila Shafique, Talha Jamshaid, Fakhar ud Din, Yasir Mehmood, Khaleeq Anwer, Qurrat ul Ain Yousafi, Talib Hussain, Ikram Ullah Khan, Muhammad Usman Ghori, Yasser Shahzad & Abid Mehmood Yousaf. (2020) Electrospun Gelatin Nanocontainers for Enhanced Biopharmaceutical Performance of Piroxicam: In Vivo and In Vitro Investigations. International Journal of Nanomedicine 15, pages 8819-8828.
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Yuan Zhu, Shuang Li, Haiqiao Wang, Michael Adu‐Frimpong, Yuanyuan Xue, Zhengqing Gu, Jiangnan Yu & Ximing Xu. (2023) Enhanced oral bioavailability of capsaicin‐loaded microencapsulation complex via electrospray technology: Preparation, in vitro and in vivo evaluation. Biopharmaceutics & Drug Disposition 44:2, pages 137-146.
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Jung Suk Kim, Fakhar ud Din, Yoo Jin Choi, Mi Ran Woo, Seunghyun Cheon, Sang Hun Ji, Seonghyeon Park, Jong Oh Kim, Yu Seok Youn, Soo-Jeong Lim, Sung Giu Jin & Han-Gon Choi. (2022) Hydroxypropyl-β-cyclodextrin-based solid dispersed granules: A prospective alternative to conventional solid dispersion. International Journal of Pharmaceutics 628, pages 122286.
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Shiyi Zhao, Chi Huang, Xuan Yue, Xuebo Li, Ping Zhou, Anxin Wu, Chonghao Chen, Yan Qu & Chen Zhang. (2022) Application advance of electrosprayed micro/nanoparticles based on natural or synthetic polymers for drug delivery system. Materials & Design 220, pages 110850.
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Abdulla Sherikar, Mohd Usman Mohd Siddique, Mahesh More, Sameer N. Goyal, Milan Milivojevic, Saad Alkahtani, Saud Alarifi, Md Saquib Hasnain & Amit Kumar Nayak. (2021) Preparation and Evaluation of Silymarin-Loaded Solid Eutectic for Enhanced Anti-Inflammatory, Hepatoprotective Effect: In Vitro–In Vivo Prospect. Oxidative Medicine and Cellular Longevity 2021, pages 1-13.
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Amna Ali, Aliyah Zaman, Elshaimaa Sayed, David Evans, Stuart Morgan, Chris Samwell, John Hall, Muhammad Sohail Arshad, Neenu Singh, Omar Qutachi, Ming-Wei Chang & Zeeshan Ahmad. (2021) Electrohydrodynamic atomisation driven design and engineering of opportunistic particulate systems for applications in drug delivery, therapeutics and pharmaceutics. Advanced Drug Delivery Reviews 176, pages 113788.
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Kaijie Qian, Lorenzo Stella, David S. Jones, Gavin P. Andrews, Huachuan Du & Yiwei Tian. (2021) Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery?. Pharmaceutics 13:6, pages 889.
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Rabia Iqbal, Omer Salman Qureshi, Abid Mehmood Yousaf, Syed Atif Raza, Hafiz Shoaib Sarwar, Gul Shahnaz, Uzma Saleem & Muhammad Farhan Sohail. (2021) Enhanced solubility and biopharmaceutical performance of atorvastatin and metformin via electrospun polyvinylpyrrolidone-hyaluronic acid composite nanoparticles. European Journal of Pharmaceutical Sciences 161, pages 105817.
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Chenghong Li, Qianqian Xu, Xianlang Chen & Rongrong Li. (2021) Bezafibrate in several aqueous mixtures of low alcohols: Solubility, solvent effect and preferential solvation. The Journal of Chemical Thermodynamics 156, pages 106208.
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Edina Szabó, Petra Záhonyi, Dániel Brecska, Dorián L. Galata, Lilla A. Mészáros, Lajos Madarász, Kristóf Csorba, Panna Vass, Edit Hirsch, Joanna Szafraniec-Szczęsny, István Csontos, Attila Farkas, Guy Van denMooter, Zsombor K. Nagy & György Marosi. (2020) Comparison of Amorphous Solid Dispersions of Spironolactone Prepared by Spray Drying and Electrospinning: The Influence of the Preparation Method on the Dissolution Properties. Molecular Pharmaceutics 18:1, pages 317-327.
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Aboothahir Afzal, Mohamed Shahin Thayyil, P.A. Sivaramakrishnan, Sailaja Urpayil & Simone Capaccioli. (2020) Molecular dynamics in the supercooled liquid and glassy states of bezafibrate and binary mixture of fenofibrate. Journal of Non-Crystalline Solids 550, pages 120407.
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