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International Journal of Nanomedicine Volume 6, 2011 - Issue
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Original Research

Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles

Yong-Zhong Du1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of China
,
Li-Li Cai1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of China
,
Jin Li1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of China
,
Meng-Dan Zhao2 Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China
,
Feng-Ying Chen2 Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China
,
Hong Yuan1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of China
&
Fu-Qiang Hu1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1559-1568 | Published online: 01 Aug 2011

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Behiye Şenel & A. Alper Öztürk. (2019) New approaches to tumor therapy with siRNA-decorated and chitosan-modified PLGA nanoparticles. Drug Development and Industrial Pharmacy 45:11, pages 1835-1848.
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Feng-Ying Chen, Jing-Jing Yan, Han-Xi Yi, Fu-Qiang Hu, Yong-Zhong Du, Hong Yuan, Jian You & Meng-Dan Zhao. (2014) TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting. International Journal of Nanomedicine 9, pages 4597-4608.
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Lifen Zhang, Zhenzhen Chen & Yanfeng Li. (2013) Dual-degradable disulfide-containing PEI–Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release. International Journal of Nanomedicine 8, pages 3689-3701.
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Edgar Marin, Maria Isabel Briceño & Catherina Caballero-George. (2013) Critical evaluation of biodegradable polymers used in nanodrugs. International Journal of Nanomedicine 8, pages 3071-3091.
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Shaheen Sultana, Mohd Rashid Khan, Mukesh Kumar, Sokindra Kumar & Mohammed Ali. (2013) Nanoparticles-mediated drug delivery approaches for cancer targeting: a review. Journal of Drug Targeting 21:2, pages 107-125.
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Ke Wang, Lina Liu, Tao Zhang, Yong-liang Zhu, Fuming Qiu, Xian-guo Wu, Xiao-lei Wang, Fu-qiang Hu & Jian Huang. (2011) Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. International Journal of Nanomedicine 6, pages 3207-3218.
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Articles from other publishers (28)

Avinash Gothwal, Richard Nii Lante Lamptey & Jagdish Singh. (2023) Multifunctionalized Cationic Chitosan Polymeric Micelles Polyplexed with pVGF for Noninvasive Delivery to the Mouse Brain through the Intranasal Route for Developing Therapeutics for Alzheimer’s Disease. Molecular Pharmaceutics.
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Anwarul Azim Akib, Ragib Shakil, Md. Mahamudul Hasan Rumon, Chanchal Kumar Roy, Ezharul Hoque Chowdhury & Al-Nakib Chowdhury. (2022) Natural and Synthetic Micelles for the Delivery of Small Molecule Drugs, Imaging Agents and Nucleic Acids. Current Pharmaceutical Design 28:17, pages 1389-1405.
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Aakriti Singh, Ganesh Yadagiri, Shabi Parvez, Om Prakash Singh, Anurag Verma, Shyam Sundar & Shyam Lal Mudavath. (2020) Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B12-stearic acid conjugate. Materials Science and Engineering: C 117, pages 111279.
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Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao & Yongmin Zhang. (2020) Recent Advances of Chitosan and its Derivatives in Biomedical Applications. Current Medicinal Chemistry 27:18, pages 3023-3045.
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Pinar Sinem Omurtag Ozgen, Sezen Atasoy, Belma Zengin Kurt, Zehra Durmus, Gulsah Yigit & Aydan Dag. (2020) Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy. Journal of Materials Chemistry B 8:15, pages 3123-3137.
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Zhongqing Wu, Kanna Xu, Jikang Min, Minchang Chen, Liping Shen, Jianxue Xu, Qi Jiang, Guohong Han, Le Pan & Haidong Li. (2020) Folate-conjugated hydrophobicity modified glycol chitosan nanoparticles for targeted delivery of methotrexate in rheumatoid arthritis. Journal of Applied Biomaterials & Functional Materials 18, pages 228080002096262.
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Maiyo & Singh. (2019) Folate-Targeted mRNA Delivery Using Chitosan-Functionalized Selenium Nanoparticles: Potential in Cancer Immunotherapy. Pharmaceuticals 12:4, pages 164.
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Pengying Wu, Dongtao Yin, Jiaming Liu, Huige Zhou, Mengyu Guo, Jing Liu, Yang Liu, Xiaobing Wang, Ying Liu & Chunying Chen. (2019) Cell membrane based biomimetic nanocomposites for targeted therapy of drug resistant EGFR-mutated lung cancer. Nanoscale 11:41, pages 19520-19528.
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Mingxia Lu, Yee Yee Khine, Fan Chen, Cheng Cao, Christopher J. Garvey, Hongxu Lu & Martina H. Stenzel. (2018) Sugar Concentration and Arrangement on the Surface of Glycopolymer Micelles Affect the Interaction with Cancer Cells. Biomacromolecules 20:1, pages 273-284.
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Chella Naveen & Nalini R. Shastri. 2019. Polysaccharide Carriers for Drug Delivery. Polysaccharide Carriers for Drug Delivery 339 363 .
P. Chanphai & H.A. Tajmir-Riahi. (2017) tRNA conjugation with folic acid-chitosan conjugates. International Journal of Biological Macromolecules 105, pages 810-815.
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Arshad Mahmood, Melanie Lanthaler, Flavia Laffleur, Christian W. Huck & Andreas Bernkop-Schnürch. (2017) Thiolated chitosan micelles: Highly mucoadhesive drug carriers. Carbohydrate Polymers 167, pages 250-258.
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Anish Babu & Rajagopal Ramesh. 2017. Industrial Applications of Marine Biopolymers. Industrial Applications of Marine Biopolymers 351 367 .
Mahsa Yousefpour Marzbali & Ahmad Yari Khosroushahi. (2017) Polymeric micelles as mighty nanocarriers for cancer gene therapy: a review. Cancer Chemotherapy and Pharmacology 79:4, pages 637-649.
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Bin Zhang, Yueying Zhang & Dongmei Yu. (2017) Lung cancer gene therapy: Transferrin and hyaluronic acid dual ligand-decorated novel lipid carriers for targeted gene delivery. Oncology Reports 37:2, pages 937-944.
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B. Layek & J. Singh. 2017. Chitosan Based Biomaterials Volume 2. Chitosan Based Biomaterials Volume 2 209 244 .
Joung-Pyo Nam & Jae-Woon Nah. (2016) Target gene delivery from targeting ligand conjugated chitosan–PEI copolymer for cancer therapy. Carbohydrate Polymers 135, pages 153-161.
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Ye Tian, Yujiao Sun, Xiaodan Wang, Georgios Kasparis & Shirui Mao. 2016. Nanobiomaterials in Drug Delivery. Nanobiomaterials in Drug Delivery 515 572 .
Joung-Pyo Nam, Kyeong-Jae Lee, Joung-Woo Choi, Chae-Ok Yun & Jae-Woon Nah. (2015) Targeting delivery of tocopherol and doxorubicin grafted-chitosan polymeric micelles for cancer therapy: In vitro and in vivo evaluation. Colloids and Surfaces B: Biointerfaces 133, pages 254-262.
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Nawal Belmadi, Patrick Midoux, Pascal Loyer, Catherine Passirani, Chantal Pichon, Tony Le Gall, Paul-Alain Jaffres, Pierre Lehn & Tristan Montier. (2015) Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration.. Biotechnology Journal 10:9, pages 1370-1389.
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Bhavani Miryala, Zhuo Zhen, Thrimoorthy Potta, Curt M. Breneman & Kaushal Rege. (2015) Parallel Synthesis and Quantitative Structure–Activity Relationship (QSAR) Modeling of Aminoglycoside-Derived Lipopolymers for Transgene Expression. ACS Biomaterials Science & Engineering 1:8, pages 656-668.
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Matthew Beard. 2014. Molecular Aspects of Botulinum Neurotoxin. Molecular Aspects of Botulinum Neurotoxin 151 170 .
Xiahui Liu, Yingying Zhang, Dongmei Ma, Hao Tang, Liang Tan, Qingji Xie & Shouzhuo Yao. (2013) Biocompatible multi-walled carbon nanotube-chitosan–folic acid nanoparticle hybrids as GFP gene delivery materials. Colloids and Surfaces B: Biointerfaces 111, pages 224-231.
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Donghong Li, Pengxi Li, Huiyun Lin, Zonglin Jiang, Linfeng Guo & Buhong Li. (2013) A novel chlorin–PEG–folate conjugate with higher water solubility, lower cytotoxicity, better tumor targeting and photodynamic activity. Journal of Photochemistry and Photobiology B: Biology 127, pages 28-37.
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Jingjing Yan, Yong-Zhong Du, Feng-Ying Chen, Jian, You, Hong Yuan & Fu-Qiang Hu. (2013) Effect of Proteins with Different Isoelectric Points on the Gene Transfection Efficiency Mediated by Stearic Acid Grafted Chitosan Oligosaccharide Micelles. Molecular Pharmaceutics 10:7, pages 2568-2577.
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Nan Zhang, Patricia Wardwell & Rebecca Bader. (2013) Polysaccharide-Based Micelles for Drug Delivery. Pharmaceutics 5:4, pages 329-352.
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Xuan Zeng, Ren-Xi Zhuo & Xian-Zheng Zhang. 2013. Functional Polymers for Nanomedicine. Functional Polymers for Nanomedicine 63 120 .
Jonathan O. Martinez, Brandon S. Brown, Nicoletta Quattrocchi, Michael Evangelopoulos, Mauro Ferrari & Ennio Tasciotti. (2012) Multifunctional to multistage delivery systems: The evolution of nanoparticles for biomedical applications. Chinese Science Bulletin 57:31, pages 3961-3971.
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