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International Journal of Nanomedicine Volume 15, 2020 - Issue
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Original Research

Self-Microemulsifying Drug Delivery System for Improved Oral Delivery and Hypnotic Efficacy of Ferulic Acid

Chang-Shun Liu1 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, People’s Republic of China;2 Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou 510515, People’s Republic of China;3 Guangdong Provincial Engineering Laboratory of Chinese Medicine Preparation Technology, Southern Medical University, Guangzhou 510515, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-2841-1795
ORCID Icon,
Li Chen4 School of Pharmacy, Zunyi Medical University, Zunyi 563000, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Yan-Nan Hu1 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, People’s Republic of China;2 Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou 510515, People’s Republic of China;3 Guangdong Provincial Engineering Laboratory of Chinese Medicine Preparation Technology, Southern Medical University, Guangzhou 510515, People’s Republic of China
,
Jin-Lian Dai4 School of Pharmacy, Zunyi Medical University, Zunyi 563000, People’s Republic of China
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Biao Ma4 School of Pharmacy, Zunyi Medical University, Zunyi 563000, People’s Republic of China
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Qing-Fa Tang1 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, People’s Republic of China;2 Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou 510515, People’s Republic of China;3 Guangdong Provincial Engineering Laboratory of Chinese Medicine Preparation Technology, Southern Medical University, Guangzhou 510515, People’s Republic of China
&
Xiao-Mei Tan1 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, People’s Republic of China;2 Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou 510515, People’s Republic of China;3 Guangdong Provincial Engineering Laboratory of Chinese Medicine Preparation Technology, Southern Medical University, Guangzhou 510515, People’s Republic of China
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Pages 2059-2070 | Published online: 25 Mar 2020

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Li Lin, Qingyong Chen, Yue Dai & Yufeng Xia. (2023) Self-Nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Madecassic Acid: In vitro and in vivo Evaluation. International Journal of Nanomedicine 18, pages 2345-2358.
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Giada Botti, Anna Bianchi, Alessandro Dalpiaz, Paola Tedeschi, Valentina Albanese, Milena Sorrenti, Laura Catenacci, Maria Cristina Bonferoni, Sarah Beggiato & Barbara Pavan. (2023) Dimeric ferulic acid conjugate as a prodrug for brain targeting after nasal administration of loaded solid lipid microparticles. Expert Opinion on Drug Delivery 0:0, pages 1-23.
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Wai Thet Aung & Veerakiet Boonkanokwong. (2023) Preparation, optimization using a mixture design, and characterization of a novel astaxanthin-loaded rice bran oil self-microemulsifying delivery system formulation. Journal of Dispersion Science and Technology 44:8, pages 1336-1349.
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Ravinder Verma, Ajeet Kaushik, Rafa Almeer, Md Habibur Rahman, Mohamed M Abdel-Daim & Deepak Kaushik. (2021) Improved Pharmacodynamic Potential of Rosuvastatin by Self-Nanoemulsifying Drug Delivery System: An in vitro and in vivo Evaluation. International Journal of Nanomedicine 16, pages 905-924.
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Articles from other publishers (20)

Tianyu Ma, Bingjie Tang, Yan Wang, Mengting Shen, Yang Ping, Lihong Wang & Jin Su. (2023) Cinnamon oil solid self-microemulsion mediates chronic mild stress-induced depression in mice by modulating monoamine neurotransmitters, corticosterone, inflammation cytokines, and intestinal flora. Heliyon 9:6, pages e17125.
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Giovanna Rassu, Milena Sorrenti, Laura Catenacci, Barbara Pavan, Luca Ferraro, Elisabetta Gavini, Maria Cristina Bonferoni, Paolo Giunchedi & Alessandro Dalpiaz. (2023) Conjugation, Prodrug, and Co-Administration Strategies in Support of Nanotechnologies to Improve the Therapeutic Efficacy of Phytochemicals in the Central Nervous System. Pharmaceutics 15:6, pages 1578.
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Aristote Buya. 2023. Advances in Novel Formulations for Drug Delivery. Advances in Novel Formulations for Drug Delivery 97 125 .
Naman Deep Raj & Dilpreet Singh. (2022) A critical appraisal on ferulic acid: Biological profile, biopharmaceutical challenges and nano formulations. Health Sciences Review 5, pages 100063.
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Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Bibiana Verlindo de Araújo, Helder Ferreira Teixeira & Letícia Scherer Koester. (2022) Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review. Pharmaceutics 14:12, pages 2663.
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Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Valquiria Linck Bassani, Helder Ferreira Teixeira & Letícia Scherer Koester. (2022) Cyclodextrin-Based Delivery Systems and Hydroxycinnamic Acids: Interactions and Effects on Crucial Parameters Influencing Oral Bioavailability—A Review. Pharmaceutics 14:11, pages 2530.
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Neha Bajwa, Srishti Naryal, Shipra Mahal, Preet Amol Singh & Ashish Baldi. (2022) Quality-by-design strategy for the development of arteether loaded solid self-micro emulsifying drug delivery systems. Journal of Drug Delivery Science and Technology 77, pages 103707.
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Deeksha Shukla, Nilay Kumar Nandi, Baljinder Singh, Arti Singh, Bhupinder Kumar, Raj Kumar Narang & Charan Singh. (2022) Ferulic acid-loaded drug delivery systems for biomedical applications. Journal of Drug Delivery Science and Technology 75, pages 103621.
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Giada Botti, Anna Bianchi, Barbara Pavan, Paola Tedeschi, Valentina Albanese, Luca Ferraro, Federico Spizzo, Lucia Del Bianco & Alessandro Dalpiaz. (2022) Effects of Microencapsulated Ferulic Acid or Its Prodrug Methyl Ferulate on Neuroinflammation Induced by Muramyl Dipeptide. International Journal of Environmental Research and Public Health 19:17, pages 10609.
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Sara Meirinho, Márcio Rodrigues, Adriana O. Santos, Amílcar Falcão & Gilberto Alves. (2022) Self-Emulsifying Drug Delivery Systems: An Alternative Approach to Improve Brain Bioavailability of Poorly Water-Soluble Drugs through Intranasal Administration. Pharmaceutics 14:7, pages 1487.
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Camila Reck Rampelotto, Viviane Gonçalves Pereira, Larissa da Silva Silveira, Aline Rossato, Alencar Kolinski Machado, Michele Rorato Sagrillo, André Gündel, Marilise Escobar Burger, Scheila Rezende Schaffazick & Cristiane de Bona da Silva. (2022) Ferulic acid-loaded nanocapsules: Evaluation of mucosal interaction, safety and antioxidant activity in human mononucleated cells. Toxicology in Vitro 78, pages 105259.
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Ye Zhang, Chizumi Abe, Koji Ochiai & Toshiro Matsui. (2021) Tissue Distribution of Orally Administered Prenylated Isoflavones, Glyceollins, in Sprague-Dawley Rats. Journal of Agricultural and Food Chemistry 69:50, pages 15165-15174.
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Monika Stompor-Gorący & Maciej Machaczka. (2021) Recent Advances in Biological Activity, New Formulations and Prodrugs of Ferulic Acid. International Journal of Molecular Sciences 22:23, pages 12889.
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Rou Tang, Rui Li, He Li, Xiao-Lei Ma, Peng Du, Xiao-You Yu, Ling Ren, Lu-Lu Wang & Wen-Sheng Zheng. (2021) Design of Hepatic Targeted Drug Delivery Systems for Natural Products: Insights into Nomenclature Revision of Nonalcoholic Fatty Liver Disease. ACS Nano 15:11, pages 17016-17046.
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Pan Gao, Zhujun Jiang, Qiao Luo, Chengqiao Mu, Mengsuo Cui & Xinggang Yang. (2021) Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine. AAPS PharmSciTech 22:7.
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Parthasarathi Subramanian. (2021) Lipid-Based Nanocarrier System for the Effective Delivery of Nutraceuticals. Molecules 26:18, pages 5510.
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Oi Jin Tan, Hooi Leong Loo, Gayathiri Thiagarajah, Uma Devi Palanisamy & Usha Sundralingam. (2021) Improving oral bioavailability of medicinal herbal compounds through lipid-based formulations – A Scoping Review. Phytomedicine 90, pages 153651.
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Ryota Araki, Akira Yasubuchi, Marina Ikegaya, Chihiro Hojo, Hayato Tachioka, Kentaro Kawai, Masaaki Omote, Ayami Kita & Takeshi Yabe. (2021) Ferulic acid alleviates abnormal behaviors in isolation-reared mice via 5-HT1A receptor partial agonist activity. Psychopharmacology 238:8, pages 2147-2154.
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Chang-Shun Liu, Ting Xia, Zhen-Ye Luo, Yuan-Yuan Wu, Yan-Nan Hu, Fei-Long Chen, Qing-Fa Tang & Xiao-Mei Tan. (2021) Network pharmacology and pharmacokinetics integrated strategy to investigate the pharmacological mechanism of Xianglian pill on ulcerative colitis. Phytomedicine 82, pages 153458.
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Pragya Baghel, Amit Roy, Shekhar Verma, Trilochan Satapathy & Sanjib Bahadur. (2020) Amelioration of lipophilic compounds in regards to bioavailability as self-emulsifying drug delivery system (SEDDS). Future Journal of Pharmaceutical Sciences 6:1.
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