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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

In vitro and in vivo studies on gelatin-siloxane nanoparticles conjugated with SynB peptide to increase drug delivery to the brain

Xin-hua Tian1 Neurosurgical Department of Affiliated Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of China
,
Feng Wei1 Neurosurgical Department of Affiliated Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of ChinaCorrespondence[email protected]
,
Tian-xiao Wang2 Research Center of Biomedical Engineering, Department of Biomaterials, College of Materials, Xiamen University, Xiamen, People’s Republic of China
,
Peng Wang1 Neurosurgical Department of Affiliated Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of China
,
Xiao-ning Lin1 Neurosurgical Department of Affiliated Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of China
,
Jun Wang2 Research Center of Biomedical Engineering, Department of Biomaterials, College of Materials, Xiamen University, Xiamen, People’s Republic of China
,
Dong Wang2 Research Center of Biomedical Engineering, Department of Biomaterials, College of Materials, Xiamen University, Xiamen, People’s Republic of China
&
Lei Ren2 Research Center of Biomedical Engineering, Department of Biomaterials, College of Materials, Xiamen University, Xiamen, People’s Republic of China;3 State Key Laboratory for Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, People’s Republic of China
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Pages 1031-1041 | Published online: 23 Feb 2012

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Fruzsina R. Walter, Ana R. Santa-Maria, Mária Mészáros, Szilvia Veszelka, András Dér & Mária A. Deli. (2021) Surface charge, glycocalyx, and blood-brain barrier function. Tissue Barriers 9:3.
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Amir Roointan, Sedigheh Kianpour, Fatemeh Memari, Molood Gandomani, Seyed Mohammad Gheibi Hayat & Soliman Mohammadi-Samani. (2018) Poly(lactic-co-glycolic acid): The most ardent and flexible candidate in biomedicine!. International Journal of Polymeric Materials and Polymeric Biomaterials 67:17, pages 1028-1049.
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Renad Alyautdin, Igor Khalin, Mohd Ismail Nafeeza, Muhammad Huzaimi Haron & Dmitry Kuznetsov. (2014) Nanoscale drug delivery systems and the blood–brain barrier. International Journal of Nanomedicine 9, pages 795-811.
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Wen Jen Lin & Li Ting Kao. (2014) Cytotoxic enhancement of hexapeptide-conjugated micelles in EGFR high-expressed cancer cells. Expert Opinion on Drug Delivery 11:10, pages 1537-1550.
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Xin-Hua Tian, Zhi-Gang Wang, Han Meng, Yu-Hua Wang, Wei Feng, Feng Wei, Zhi-Chun Huang, Xiao-Ning Lin & Lei Ren. (2013) Tat peptide-decorated gelatin-siloxane nanoparticles for delivery of CGRP transgene in treatment of cerebral vasospasm. International Journal of Nanomedicine 8, pages 865-876.
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Chia Wen Liu & Wen Jen Lin. (2013) Using doxorubicin and siRNA-loaded heptapeptide-conjugated nanoparticles to enhance chemosensitization in epidermal growth factor receptor high-expressed breast cancer cells. Journal of Drug Targeting 21:8, pages 776-786.
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Kalpana Nagpal, Shailendra Kumar Singh & Dina Nath Mishra. (2013) Drug targeting to brain: a systematic approach to study the factors, parameters and approaches for prediction of permeability of drugs across BBB. Expert Opinion on Drug Delivery 10:7, pages 927-955.
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Sonia M Lombardo, Marc Schneider, Akif E Türeli & Nazende Günday Türeli. (2020) Key for crossing the BBB with nanoparticles: the rational design. Beilstein Journal of Nanotechnology 11, pages 866-883.
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