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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

Role of hydroxypropyl-β-cyclodextrin on freeze-dried and gamma-irradiated PLGA and PLGA–PEG diblock copolymer nanospheres for ophthalmic flurbiprofen delivery

Estefanía Vega1 Department of Physical Chemistry, Institute of Nanoscience and Nanotechnology, Faculty of Pharmacy, University of Barcelona, Barcelona, SpainCorrespondence[email protected]
,
M Antònia Egea1 Department of Physical Chemistry, Institute of Nanoscience and Nanotechnology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
,
Ana Cristina Calpena2 Department of Biopharmacy and Pharmaceutical Technology, Institute of Nanoscience and Nanotechnology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
,
Marta Espina1 Department of Physical Chemistry, Institute of Nanoscience and Nanotechnology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
&
M Luisa García1 Department of Physical Chemistry, Institute of Nanoscience and Nanotechnology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Pages 1357-1371 | Published online: 09 Mar 2012

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Shilpa Kakkar, Mandeep Singh, Sankunny Mohan Karuppayil, Jayant S. Raut, Fabrizio Giansanti, Laura Papucci, Nicola Schiavone, T. C. Nag, Nan Gao, Fu-Shin X. Yu, Mohhammad Ramzan & Indu Pal Kaur. (2021) Lipo-PEG nano-ocular formulation successfully encapsulates hydrophilic fluconazole and traverses corneal and non-corneal path to reach posterior eye segment. Journal of Drug Targeting 29:6, pages 631-650.
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Yi Huang, Qi Tao, Dongzhi Hou, Sheng Hu, Shuangyan Tian, Yanzhong Chen, Ruyi Gui, Lingling Yang & Yao Wang. (2017) A novel ion-exchange carrier based upon liposome-encapsulated montmorillonite for ophthalmic delivery of betaxolol hydrochloride. International Journal of Nanomedicine 12, pages 1731-1745.
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Gladys Rosario Ramos Yacasi, María Luisa García López, Marta Espina García, Alexander Parra Coca & Ana Cristina Calpena Campmany. (2016) Influence of freeze-drying and γ-irradiation in preclinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using d-(+)-trehalose and polyethylene glycol. International Journal of Nanomedicine 11, pages 4093-4106.
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Bina Gidwani & Amber Vyas. (2016) Formulation, characterization and evaluation of cyclodextrin-complexed bendamustine-encapsulated PLGA nanospheres for sustained delivery in cancer treatment. Pharmaceutical Development and Technology 21:2, pages 161-171.
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Yingying Zhao, Chaonan Sun, Feng Shi, Caleb Kesse Firempong, Jiangnan Yu, Ximing Xu & Weiming Zhang. (2016) Preparation, characterization, and pharmacokinetics study of capsaicin via hydroxypropyl-beta-cyclodextrin encapsulation. Pharmaceutical Biology 54:1, pages 130-138.
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Aimee Vasconcelos, Estefania Vega, Yolanda Pérez, María J Gómara, María Luisa García & Isabel Haro. (2015) Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery. International Journal of Nanomedicine 10, pages 609-631.
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